Focal Dystonia

Common Name(s)

Focal Dystonia

Focal dystonia is a movement disorder that is localized to a specific part of the body. The dystonias are a group of movement problems characterized by involuntary, sustained muscle contractions, tremors, and other uncontrolled movements. Focal task-specific dystonia, or FTSD, interferes with the performance of particular tasks, such as writing, playing a musical instrument, or participating in a sport. Additionally, FTSD has been reported in tailors, shoemakers, hair stylists, and people who frequently type or use a computer mouse. While the abnormal movements associated with focal dystonia are usually painless, they can cause high levels of anxiety. The causes of focal dystonia are unknown, although the disorder likely results from a combination of genetic and environmental factors. It is possible that the different forms of FTSD have different underlying causes. Researchers have found that at least some cases are related to malfunction of the basal ganglia, which are structures deep within the brain that help start and control movement. Most cases of focal dystonia are sporadic, which means they occur in people with no history of the condition in their family. However, at least 10 percent of affected individuals have a family history which seems to follow an autosomal dominant pattern of inheritance.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Focal Dystonia" for support, advocacy or research.

The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Focal Dystonia" for support, advocacy or research.

The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

https://www.dystonia-parkinson.org

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Focal Dystonia" returned 65 free, full-text research articles on human participants. First 3 results:

Psychiatric associations of adult-onset focal dystonia phenotypes.
 

Author(s): Brian D Berman, Johanna Junker, Erika Shelton, Stefan H Sillau, H A Jinnah, Joel S Perlmutter, Alberto J Espay, Joseph Jankovic, Marie Vidailhet, Cecilia Bonnet, William Ondo, Irene A Malaty, Ramón Rodríguez, William M McDonald, Laura Marsh, Mateusz Zurowski, Tobias Bäumer, Norbert Brüggemann

Journal: J. Neurol. Neurosurg. Psychiatry. 2017 Jul;88(7):595-602.

 

Depression and anxiety frequently accompany the motor manifestations of isolated adult-onset focal dystonias. Whether the body region affected when this type of dystonia first presents is associated with the severity of these neuropsychiatric symptoms is unknown.

Last Updated: 31 Dec 1969

Go To URL
Combined focal myoclonus and dystonia secondary to a cerebellar hemorrhage: a case report.
 

Author(s): Guangxun Shen, Guangxian Nan, Chae-Won Shin, Hyeyoung Park, Kwee-Yum Lee, Beomseok Jeon

Journal:

 

Myoclonus is a clinical sign characterized by sudden, brief jerky, shock-like involuntary movements of a muscle or group of muscles. Dystonia is defined as a syndrome of sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures. Cases ...

Last Updated: 31 Dec 1969

Go To URL
Effects of cerebellar theta-burst stimulation on arm and neck movement kinematics in patients with focal dystonia.
 

Author(s): Matteo Bologna, Giulia Paparella, Andrea Fabbrini, Giorgio Leodori, Lorenzo Rocchi, Mark Hallett, Alfredo Berardelli

Journal: Clin Neurophysiol. 2016 Nov;127(11):3472-3479.

 

To investigate the cerebellar inhibitory influence on the primary motor cortex in patients with focal dystonia using a cerebellar continuous theta-burst stimulation protocol (cTBS) and to evaluate any relationship with movement abnormalities.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Focal Dystonia" returned 8 free, full-text review articles on human participants. First 3 results:

Botulinum toxin physiology in focal hand and cranial dystonia.
 

Author(s): Barbara Illowsky Karp

Journal:

 

The safety and efficacy of botulinum toxin for the treatment of focal hand and cranial dystonias are well-established. Studies of these adult-onset focal dystonias reveal both shared features, such as the dystonic phenotype of muscle hyperactivity and overflow muscle contraction and ...

Last Updated: 31 Dec 1969

Go To URL
Botulinum toxin as treatment for focal dystonia: a systematic review of the pharmaco-therapeutic and pharmaco-economic value.
 

Author(s): E Zoons, M G W Dijkgraaf, J M Dijk, I N van Schaik, M A Tijssen

Journal: J. Neurol.. 2012 Dec;259(12):2519-26.

 

Focal dystonia is a common, invalidating neurologic condition characterized by involuntary, sustained muscle contractions causing twisting movements and abnormal postures in one body part. Currently, botulinum toxin is the treatment of first choice. We performed a systematic review ...

Last Updated: 31 Dec 1969

Go To URL
Focal dystonia in musicians.
 

Author(s): R Aránguiz, P Chana-Cuevas, D Alburquerque, M León

Journal: Neurologia. ;26(1):45-52.

 

A special group of focal dystonia is that known as occupational, which include dystonic disorders triggered by repetitive motor activity, closely associated with the professional activity of a specific task that the affected person performs. In this sense, musicians are a population ...

Last Updated: 31 Dec 1969

Go To URL
 
 
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Loss of Depotentiation in Focal Dystonia
 

Status: Recruiting

Condition Summary: Focal Dystonia; Healthy Volunteers

 

Last Updated: 23 Sep 2017

Go to URL
Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia
 

Status: Recruiting

Condition Summary: Spasticity; Focal Dystonia; Tremor, Limb

 

Last Updated: 19 Oct 2017

Go to URL
Deep Brain Stimulation Surgery for Focal Hand Dystonia
 

Status: Not yet recruiting

Condition Summary: Dystonia; Focal Dystonia; Musician's Dystonia

 

Last Updated: 18 Oct 2017

Go to URL