Fibrous Dysplasia

Common Name(s)

Fibrous Dysplasia

Fibrous dysplasia is a progressive bone disorder that is characterized by the replacement of normal bone with weaker tissues, such as fibrous tissue and woven bone.  It may involve one bone (monostotic) or multiple bones (polyostotic).   Though many individuals with this condition do not have any symptoms, others may have bone pain, abnormally shaped bones, or an increased risk of breaking bones.   This condition can occur alone or as part of a genetic disorder, such as McCune-Albright syndrome.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibrous Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibrous Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fibrous Dysplasia" returned 143 free, full-text research articles on human participants. First 3 results:

Hyperostotic esthesioneuroblastoma: rare variant and fibrous dysplasia mimicker.
 

Author(s): Manzoor Ahmed, Phillip Daniel Knott

Journal: Korean J Radiol. ;15(1):156-60.

 

A 65-year-old male presented with a 3-year history of orbital symptoms. An imaging-based diagnosis of fibrous dysplasia involving the skull base was made at another institution. CT showed a diffuse sinonasal mass and ground-glass appearance of the bones of the anterior skull base ...

Last Updated: 5 Feb 2014

Go To URL
[How can an ossifying fibroma mimic a fibrous dysplasia? Case report].
 

Author(s): Amany Landolsi, Souheil Jbali, Maha Ben Rejeb, Najoua Ben Slimen, Karima Zitouni, Issam Zairi, Ali Adouani

Journal: Tunis Med. 2013 Nov;91(11):680-1.

 

Last Updated: 17 Dec 2013

Go To URL
Dental perspectives in fibrous dysplasia and McCune-Albright syndrome.
 

Author(s): Sunday O Akintoye, Alison M Boyce, Michael T Collins

Journal: Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Sep;116(3):e149-55.

 

McCune-Albright syndrome (MAS) is a rare multisystem disorder characterized by the triad of polyostotic fibrous dysplasia (FD), endocrine disorders, and café-au-lait skin pigmentation. Ninety percent of MAS patients have FD lesions in the craniofacial area, resulting in significant ...

Last Updated: 19 Aug 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fibrous Dysplasia" returned 15 free, full-text review articles on human participants. First 3 results:

[Medical therapy of polyostotic fibrous dysplasia of the spinal column].
 

Author(s): Feng-liang Wu, Liang Jiang, Shao-min Yang, Chen Liu, Xiao-guang Liu, Feng Wei, Miao Yu, Zhong-jun Liu

Journal: Beijing Da Xue Xue Bao. 2013 Dec;45(6):950-5.

 

To discuss treatments of spinal polyostotic fibrous dysplasia (PFD) and their clinical outcomes.

Last Updated: 17 Dec 2013

Go To URL
Fibrous dysplasia and fibroblast growth factor-23 regulation.
 

Author(s): Alison M Boyce, Nisan Bhattacharyya, Michael T Collins

Journal: Curr Osteoporos Rep. 2013 Jun;11(2):65-71.

 

Fibrous dysplasia (FD) is a skeletal disorder caused by activating mutations in Gsα that result in elevations in cAMP. A feature of FD is elevated blood levels of the bone cell-derived phosphaturic hormone, fibroblast growth factor-23 (FGF23). FGF23 regulates serum phosphorus and ...

Last Updated: 2 May 2013

Go To URL
Fibrous dysplasia of the inferior turbinate.
 

Author(s): Hyun Joo Park, Min-Sun Cho, Seung-Sin Lee

Journal: Int J Clin Exp Pathol. 2013 ;6(3):531-5.

 

Fibrous dysplasia (FD) is a benign skeletal disorder in which abnormally overgrowing bony lesion replaces normal bone. FD can affect one bone (monostotic form) or multiple bones (polyostotic form). The craniofacial bones are involved in about 10% of subjects with monostotic FD. However, ...

Last Updated: 15 Feb 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome
 

Status: Recruiting

Condition Summary: Polyostotic Fibrous Dysplasia

 

Last Updated: 3 Oct 2014

Go to URL
TOCILIZUMAB IN FIBROUS DYSPLASIA OF BONE
 

Status: Recruiting

Condition Summary: Fibrous Dysplasia of Bone

 

Last Updated: 14 Mar 2013

Go to URL
Effect of Risedronate on Bone Morbidity in Fibrous Dysplasia of Bone
 

Status: Recruiting

Condition Summary: Fibrous Dysplasia of Bone

 

Last Updated: 29 Dec 2011

Go to URL