Fibrous Dysplasia

Common Name(s)

Fibrous Dysplasia

Fibrous dysplasia is a progressive bone disorder that is characterized by the replacement of normal bone with weaker tissues, such as fibrous tissue and woven bone.  It may involve one bone (monostotic) or multiple bones (polyostotic).   Though many individuals with this condition do not have any symptoms, others may have bone pain, abnormally shaped bones, or an increased risk of breaking bones.   This condition can occur alone or as part of a genetic disorder, such as McCune-Albright syndrome.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibrous Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fibrous Dysplasia" returned 211 free, full-text research articles on human participants. First 3 results:

Radiographic classification and treatment of fibrous dysplasia of the proximal femur: 227 femurs with a mean follow-up of 6 years.
 

Author(s): Xuelei Zhang, Chunyu Chen, Hong Duan, Chongqi Tu

Journal:

 

Research into the optimal treatment of fibrous dysplasia has been limited by the lack of an established classification system for the disease. The purposes of this study were to develop a radiographic classification for fibrous dysplasia of the proximal femur and to test this classification's ...

Last Updated: 16 Nov 2015

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[Fibrous dysplasia: overview].
 

Author(s): Nessrine Akasbi, Fatima Ezzahra Abourazzak, Sofia Talbi, Latifa Tahiri, Taoufik Harzy

Journal:

 

Last Updated: 24 Sep 2015

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Tocilizumab in the treatment of a polyostotic variant of fibrous dysplasia of bone.
 

Author(s): Hubert de Boysson, Alison Johnson, Naceur Hablani, Walid Hajlaoui, Christophe Auzary, Loïk Geffray

Journal: Rheumatology (Oxford). 2015 Sep;54(9):1747-9.

 

Last Updated: 15 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fibrous Dysplasia" returned 25 free, full-text review articles on human participants. First 3 results:

Malignant transformation in monostotic fibrous dysplasia: clinical features, imaging features, outcomes in 10 patients, and review.
 

Author(s): Nan Qu, Weiwu Yao, Xiaojiang Cui, Huizhen Zhang

Journal: Medicine (Baltimore). 2015 Jan;94(3):e369.

 

Malignant transformation in fibrous dysplasia (FD) is uncommon. The purpose of this study was to investigate clinical and imaging features, and outcomes of malignant transformation in monostotic FD.Data for 10 pathologically confirmed malignant transformations in monostotic FD from ...

Last Updated: 27 Jan 2015

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Locally aggressive fibrous dysplasia mimicking malignancy: a report of four cases and review of the literature.
 

Author(s): Saravanaraja Muthusamy, Ty Subhawong, Sheila A Conway, H Thomas Temple

Journal: Clin. Orthop. Relat. Res.. 2015 Feb;473(2):742-50.

 

Fibrous dysplasia is a benign fibroosseous bone tumor that accounts for 5% to 10% of benign bone tumors. It can present as monostotic fibrous dysplasia (70% to 80%), polyostotic fibrous dysplasia (20% to 30%), McCune-Albright syndrome (2% to 3%), or Mazabraud's syndrome in rare cases. ...

Last Updated: 15 Jan 2015

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Monostotic fibrous dysplasia involving occipital bone: a case report and review of literature.
 

Author(s): Recep Basaran, Mustafa Kaksi, Erdal Gur, Mustafa Efendioglu, Ece Balkuv, Aydin Sav

Journal:

 

Fibrous dysplasia (FD) is a progressive systemic bone tumour of young and it can be seen on cranial bones. FD is divided into three types according to radiological features. The second most common subtype is polyostotic subtype. With this article, we aimed to review and present clinical ...

Last Updated: 6 Mar 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

TOCILIZUMAB IN FIBROUS DYSPLASIA OF BONE
 

Status: Recruiting

Condition Summary: Fibrous Dysplasia of Bone

 

Last Updated: 14 Mar 2013

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Effect of Risedronate on Bone Morbidity in Fibrous Dysplasia of Bone
 

Status: Recruiting

Condition Summary: Fibrous Dysplasia of Bone

 

Last Updated: 29 Dec 2011

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Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome
 

Status: Recruiting

Condition Summary: McCune Albright Syndrome

 

Last Updated: 28 Jul 2016

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