Fibrous Dysplasia

Common Name(s)

Fibrous Dysplasia

Fibrous dysplasia is a progressive bone disorder that is characterized by the replacement of normal bone with weaker tissues, such as fibrous tissue and woven bone.  It may involve one bone (monostotic) or multiple bones (polyostotic).   Though many individuals with this condition do not have any symptoms, others may have bone pain, abnormally shaped bones, or an increased risk of breaking bones.   This condition can occur alone or as part of a genetic disorder, such as McCune-Albright syndrome.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibrous Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fibrous Dysplasia" returned 218 free, full-text research articles on human participants. First 3 results:

Functional and radiological outcomes of a minimally invasive surgical approach to monostotic fibrous dysplasia.
 

Author(s): Mamer S Rosario, Katsuhiro Hayashi, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Yuta Taniguchi, Hiroyuki Tsuchiya

Journal:

 

Reports showing high recurrence rates for intralesional curettage and bone grafting have made the current treatment principle for fibrous dysplasia controversial. This study aimed to report the postoperative clinical outcomes from three minimally invasive surgical strategies we use ...

Last Updated: 6 Jan 2017

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[Monostotic fibrous dysplasia].
 

Author(s): Agustina Sosa Beláustegui, Daniela Tolosa Koury, Esteban Bercellini, Silvana Saldaña, Bárbara Rellan, Patricia Aruj

Journal: Medicina (B Aires). ;76(4):251.

 

Last Updated: 31 Aug 2016

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Pseudomyogenic hemangioendothelioma secondary to fibrous dysplasia of the left lower extremity in a 14-year-old female: a case report.
 

Author(s): Conglin Ye, Xiaolong Yu, Jin Zeng, Hucheng Liu, Min Dai

Journal:

 

Pseudomyogenic hemangioendothelioma is a rare soft tissue tumor usually found in young adults, predominantly males. Fibrous dysplasia is a common benign bone tumor, which accounts for 5~7 % of all the primary benign bone tumors. However, pseudomyogenic hemangioendothelioma secondary ...

Last Updated: 29 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fibrous Dysplasia" returned 26 free, full-text review articles on human participants. First 3 results:

Craniofacial Fibrous Dysplasia Involving the Orbit: A Case Report and Literature Review.
 

Author(s): Leonard Tang Yew Leong, Benjamin Julian Chang Chong Ming

Journal: Asia Pac J Ophthalmol (Phila). ;4(3):151-4.

 

Craniofacial fibrous dysplasia is a benign slowly progressive disease in which normal craniofacial bones are replaced by immature fibro-osseous tissue. Orbital involvement may present as visual loss in some patients. The etiology of visual loss in orbital fibrous dysplasia is still ...

Last Updated: 13 Jun 2015

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Malignant transformation in monostotic fibrous dysplasia: clinical features, imaging features, outcomes in 10 patients, and review.
 

Author(s): Nan Qu, Weiwu Yao, Xiaojiang Cui, Huizhen Zhang

Journal: Medicine (Baltimore). 2015 Jan;94(3):e369.

 

Malignant transformation in fibrous dysplasia (FD) is uncommon. The purpose of this study was to investigate clinical and imaging features, and outcomes of malignant transformation in monostotic FD.Data for 10 pathologically confirmed malignant transformations in monostotic FD from ...

Last Updated: 27 Jan 2015

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Locally aggressive fibrous dysplasia mimicking malignancy: a report of four cases and review of the literature.
 

Author(s): Saravanaraja Muthusamy, Ty Subhawong, Sheila A Conway, H Thomas Temple

Journal: Clin. Orthop. Relat. Res.. 2015 Feb;473(2):742-50.

 

Fibrous dysplasia is a benign fibroosseous bone tumor that accounts for 5% to 10% of benign bone tumors. It can present as monostotic fibrous dysplasia (70% to 80%), polyostotic fibrous dysplasia (20% to 30%), McCune-Albright syndrome (2% to 3%), or Mazabraud's syndrome in rare cases. ...

Last Updated: 15 Jan 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Interest of Serum Periostin Dosage in Patients With Bone Fibrous Dysplasia
 

Status: Recruiting

Condition Summary: Bone Fibrous Dysplasia

 

Last Updated: 23 Aug 2016

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Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome
 

Status: Recruiting

Condition Summary: McCune Albright Syndrome

 

Last Updated: 30 Jun 2017

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PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome
 

Status: Not yet recruiting

Condition Summary: Nervous System Disease

 

Last Updated: 11 Jul 2017

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