AIDS-HIV

Common Name(s)

AIDS-HIV, HIV/AIDS, AIDS

Acquired Immune Deficiency Syndrome or AIDS is the final stage of an Human Immunodeficiency Virus (HIV) infection. HIV is a human retrovirus. The term retrovirus means that the virus can replicate inside a human cell. The retrovirus is an RNA virus; it converts itself into DNA and inserts itself into the cell’s genome. Once it is part of the cell’s genetic code, the virus is then produced by the cell’s replication machinery. Once enough of the virus has been produced within the cell, the cell dies and releases the virus into the body. HIV attacks the cells of your immune system, specifically the CD4 cells. CD4 cells include T helper cells, monocytes, macrophages, and dendritic cells. The virus decreases the number CD4 cells in the body, therefore diminishing the body’s ability to fight infection. Once your number of CD4 cells has fallen below 200 per cubic millimeter of blood, you will be diagnosed with AIDS. AIDS in it of itself is not lethal, however, because of the extensive damage to a person’s immune system, it allows for several tumors opportunistic infections, such as invasive cervical cancer, pneumonia, lymphoma, and tuberculosis, to develop. The development of AIDS can be delayed through antiretroviral therapy in HIV infected individuals. HIV is a sexually transmitted infection, but HIV can also be transmitted by contaminated hypodermic needles and blood transfusions, as well as from infected mother to child during pregnancy, delivery, and breastfeeding. Early symptoms of an HIV infection include fever, rash, night sweats, headaches, sore throat, fatigue, and a general feeling of having the flu, but many individuals who are HIV positive do not have any symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "AIDS-HIV" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 26 Oct 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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The Living Affected Corporation (LACorp)

LACorp transforms communities to Holistic Health through prevention, education and advocacy.

Last Updated: 29 Apr 2014

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

Last Updated: 20 May 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "AIDS-HIV" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 26 Oct 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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The Living Affected Corporation (LACorp)

LACorp transforms communities to Holistic Health through prevention, education and advocacy.

http://www.livingaffected.org

Last Updated: 29 Apr 2014

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

http://www.thewellproject.org/

Last Updated: 20 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "AIDS-HIV" returned 11 free, full-text research articles on human participants. First 3 results:

Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142.
 

Author(s): Kevin C Olivieri, Robert M Scoggins, Brooks Broderick, Maria L C Powell, Melissa A Alexander, Marie-Louise Hammarskjöld, David Rekosh, David Camerini

Journal:

 

AIDS-associated, CCR5-tropic (R5) HIV-1 clones, isolated from a patient that never developed CXCR4-tropic HIV-1, replicate to a greater extent and cause greater cytopathic effects than R5 HIV-1 clones isolated before the onset of AIDS. Previously, we showed that HIV-1 Env substantially ...

Last Updated: 26 Jun 2008

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Bile duct-duodenal fistula caused by AIDS/HIV-associated tuberculosis.
 

Author(s): Carlos Patino, Belchor Fontes, Renato Sergio Poggetti, Cornelius Mitteldorf, Conrado Alvarenga, Dario Birolini

Journal: Rev Hosp Clin Fac Med Sao Paulo. ;58(4):223-6.

 

Although infrequent, digestive fistulae in HIV/AIDS patients have been reported throughout the digestive tract from the esophagus to the anus, with predominance of esophageal fistulae. AIDS/HIV-associated opportunistic infections may invade the digestive system and lead to fistula ...

Last Updated: 9 Oct 2003

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No sex or safe sex? Mothers' and adolescents' discussions about sexuality and AIDS/HIV.
 

Author(s): Eva S Lefkowitz, Tanya L Boone, Terry Kit-fong Au, Marian Sigman

Journal: Health Educ Res. 2003 Jun;18(3):341-51.

 

The authors examined in this study whether mothers and adolescents discussed abstinence and safer sex, and how these discussions relate to demographic characteristics. Fifty mother-adolescent dyads (25 girls and 25 boys, aged 11-15) participated in videotaped conversations about two ...

Last Updated: 27 Jun 2003

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "AIDS-HIV" returned 2 free, full-text review articles on human participants. First 3 results:

The end of AIDS: HIV infection as a chronic disease.
 

Author(s): Steven G Deeks, Sharon R Lewin, Diane V Havlir

Journal: Lancet. 2013 Nov;382(9903):1525-33.

 

The success of antiretroviral therapy has led some people to now ask whether the end of AIDS is possible. For patients who are motivated to take therapy and who have access to lifelong treatment, AIDS-related illnesses are no longer the primary threat, but a new set of HIV-associated ...

Last Updated: 4 Nov 2013

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ABC of AIDS. HIV infection and AIDS in the developing world.
 

Author(s): A D Grant, K M De Cock

Journal: BMJ. 2001 Jun;322(7300):1475-8.

 

Last Updated: 15 Jun 2001

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of People With HIV Infection Who Have High Viral Loads Despite Combination Antiretroviral Therapy
 

Status: Recruiting

Condition Summary: Acquired Immune Deficiency Syndrome Virus; Acquired Immunodeficiency Syndrome Virus; AIDS Virus; Human Immunodeficiency Virus; Human Immunodeficiency Viruses

 

Last Updated: 13 Sep 2014

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A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma
 

Status: Recruiting

Condition Summary: Kaposi's Sarcoma; HIV+; HIV Positive; AIDS

 

Last Updated: 3 Sep 2014

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Effect of Cenicriviroc on HIV Neurocognitive Impairment
 

Status: Recruiting

Condition Summary: AIDS Dementia Complex; HIV-1-Associated Cognitive Motor Complex; Human Immunodeficiency Virus

 

Last Updated: 29 Apr 2014

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