Familial Prostate Cancer

Common Name(s)

Familial Prostate Cancer

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Prostate Cancer" for support, advocacy or research.

FORCE: Facing Our Risk of Cancer Empowered

FORCE is a national nonprofit dedicated to fighting hereditary breast and ovarian cancer. With 50 outreach groups throughout the U.S., and international affiliates, FORCE programs provide support, education, advocacy, awareness and research specific to hereditary cancers. Our programs serve anyone with a BRCA mutation or a family history of cancer. FORCE was founded on the principle that no one should have to face hereditary breast and ovarian cancer alone.

Last Updated: 5 May 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Prostate Cancer" for support, advocacy or research.

FORCE: Facing Our Risk of Cancer Empowered

FORCE is a national nonprofit dedicated to fighting hereditary breast and ovarian cancer. With 50 outreach groups throughout the U.S., and international affiliates, FORCE programs provide support, education, advocacy, awareness and research specific to hereditary cancers. Our programs serve anyone with a BRCA mutation or a family history of cancer. FORCE was founded on the principle that no one should have to face hereditary breast and ovarian cancer alone.

http://www.facingourrisk.org

Last Updated: 5 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Prostate Cancer" returned 58 free, full-text research articles on human participants. First 3 results:

Role of Genetic Polymorphisms in the Development and Prognosis of Sporadic and Familial Prostate Cancer.
 

Author(s): Sabrina T Reis, Nayara I Viana, Katia R M Leite, Erico Diogenes, Alberto A Antunes, Alexandre Iscaife, Adriano J Nesrallah, Carlo C Passerotti, Victor Srougi, José Pontes-Junior, Mary Ellen Salles, William C Nahas, Miguel Srougi

Journal:

 

Our aim was to evaluate the role of 20 genetic polymorphisms in the development and prognosis of sporadic and familial PC. A case-control study of 185 patients who underwent radical prostatectomy from 1997 to 2011. These patients were divided into two groups based on their family ...

Last Updated: 1 Dec 2016

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Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.
 

Author(s): Craig C Teerlink, Daniel Leongamornlert, Tokhir Dadaev, Alun Thomas, James Farnham, Robert A Stephenson, Shaun Riska, Shannon K McDonnell, Daniel J Schaid, William J Catalona, S Lilly Zheng, Kathleen A Cooney, Anna M Ray, Kimberly A Zuhlke, Ethan M Lange, Graham G Giles, Melissa C Southey, Liesel M Fitzgerald, Antje Rinckleb, Manuel Luedeke, Christiane Maier, Janet L Stanford, Elaine A Ostrander, Elina M Kaikkonen, Csilla Sipeky, Teuvo Tammela, Johanna Schleutker, Kathleen E Wiley, Sarah D Isaacs, Patrick C Walsh, William B Isaacs, Jianfeng Xu, Geraldine Cancel-Tassin, Olivier Cussenot, Diptasri Mandal, Cecelia Laurie, Cathy Laurie, , , Stephen N Thibodeau, Rosalind A Eeles, Zsofia Kote-Jarai, Lisa Cannon-Albright

Journal: Hum. Genet.. 2016 Aug;135(8):923-38.

 

Previous genome-wide association studies (GWAS) of prostate cancer risk focused on cases unselected for family history and have reported over 100 significant associations. The International Consortium for Prostate Cancer Genetics (ICPCG) has now performed a GWAS of 2511 (unrelated) ...

Last Updated: 18 Jul 2016

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Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer.
 

Author(s): Emmanuelle Nicolas, Sanjeevani Arora, Yan Zhou, Ilya G Serebriiskii, Mark D Andrake, Elizabeth D Handorf, Dale L Bodian, Joseph G Vockley, Roland L Dunbrack, Eric A Ross, Brian L Egleston, Michael J Hall, Erica A Golemis, Veda N Giri, Mary B Daly

Journal: Oncotarget. 2015 Nov;6(37):39614-33.

 

Risk assessment for prostate cancer is challenging due to its genetic heterogeneity. In this study, our goal was to develop an operational framework to select and evaluate gene variants that may contribute to familial prostate cancer risk. Drawing on orthogonal sources, we developed ...

Last Updated: 3 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Prostate Cancer" returned 4 free, full-text review articles on human participants. First 3 results:

Screening for familial and hereditary prostate cancer.
 

Author(s): Henry T Lynch, Omofolasade Kosoko-Lasaki, Stephen W Leslie, Marc Rendell, Trudy Shaw, Carrie Snyder, Anthony V D'Amico, Sarah Buxbaum, William B Isaacs, Stacy Loeb, Judd W Moul, Isaac Powell

Journal: Int. J. Cancer. 2016 Jun;138(11):2579-91.

 

Prostate cancer (PC) has the highest degree of genetic transmission of any form of malignancy. In some families, the hereditary pattern is so strong as to mimic an autosomal dominance trait. We reviewed the known predisposing genetic markers to assess possible strategies for screening ...

Last Updated: 21 Mar 2016

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Site-specific familial aggregation of prostate cancer.
 

Author(s): Bas A J Verhage, Katja K H Aben, J Alfred Witjes, Huub Straatman, Jack A Schalken, Lambertus A L M Kiemeney

Journal: Int. J. Cancer. 2004 Apr;109(4):611-7.

 

Over the last decade, epidemiologic evidence has accumulated in favor of a significant but heterogeneous hereditary component in prostate cancer (PC) susceptibility. In order to map and clone PC susceptibility genes, stratification of PC families into genetically homogeneous groups ...

Last Updated: 1 Mar 2004

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A systematic review and meta-analysis of familial prostate cancer risk.
 

Author(s): L E Johns, R S Houlston

Journal: BJU Int.. 2003 Jun;91(9):789-94.

 

To identify published studies quantifying familial prostate cancer risks in relatives of prostate cancer cases and, by meta-analysis, obtain more precise estimates of familial risk according to the family history.

Last Updated: 3 Jun 2003

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.