Familial Polyposis

Common Name(s)

Familial Polyposis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Polyposis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Polyposis" returned 342 free, full-text research articles on human participants. First 3 results:

Upper GI tract lesions in familial adenomatous polyposis (FAP): enrichment of pyloric gland adenomas and other gastric and duodenal neoplasms.
 

Author(s): Laura D Wood, Safia N Salaria, Michael W Cruise, Francis M Giardiello, Elizabeth A Montgomery

Journal: Am. J. Surg. Pathol.. 2014 Mar;38(3):389-93.

 

Patients with familial adenomatous polyposis (FAP), an autosomal dominant cancer predisposition syndrome caused by mutations in the APC gene, develop neoplasms in both the upper and lower gastrointestinal (GI) tract. To clarify the upper GI tract lesions in FAP patients in a tertiary ...

Last Updated: 14 Feb 2014

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Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls.
 

Author(s): Bjorn W H van Heumen, Hennie M J Roelofs, René H M te Morsche, Fokko M Nagengast, Wilbert H M Peters

Journal:

 

Familial adenomatous polyposis (FAP) is a disease characterized by the development of hundreds to thousands of adenomatous polyps in the colorectum early in life. Virtually all patients with FAP will develop colorectal cancer before the age of 40 to 50 years, unless prophylactic colectomy ...

Last Updated: 9 Dec 2013

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Preventive effects of low-dose aspirin on colorectal adenoma growth in patients with familial adenomatous polyposis: double-blind, randomized clinical trial.
 

Author(s): Hideki Ishikawa, Keiji Wakabayashi, Sadao Suzuki, Michihiro Mutoh, Keiji Hirata, Tomiyo Nakamura, Ikuko Takeyama, Atsuko Kawano, Nobuhisa Gondo, Takashi Abe, Shinkan Tokudome, Chiho Goto, Nariaki Matsuura, Toshiyuki Sakai

Journal: Cancer Med. 2013 Feb;2(1):50-6.

 

There are several reports of clinical trials of aspirin in sporadic colon cancer. However, only one double-blind trial of aspirin in patients with familial adenomatous polyposis (FAP) has been reported to date. This double-blind, randomized, placebo-controlled clinical trial was therefore ...

Last Updated: 17 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Polyposis" returned 25 free, full-text review articles on human participants. First 3 results:

Risk of ileal pouch neoplasms in patients with familial adenomatous polyposis.
 

Author(s): Masahiro Tajika, Yasumasa Niwa, Vikram Bhatia, Tsutomu Tanaka, Makoto Ishihara, Kenji Yamao

Journal: World J. Gastroenterol.. 2013 Oct;19(40):6774-83.

 

Restorative proctocolectomy is the most common surgical option for patients with familial adenomatous polyposis (FAP). However, adenomas may develop in the ileal pouch mucosa over time, and even carcinoma in the pouch has been reported. We therefore reviewed the prevalence, nature, ...

Last Updated: 4 Nov 2013

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Chemoprevention in familial adenomatous polyposis.
 

Author(s): Brian Kim, Francis M Giardiello

Journal: Best Pract Res Clin Gastroenterol. 2011 Aug;25(4-5):607-22.

 

Familial adenomatous polyposis (FAP) predictably leads to adenomas and eventual adenocarcinomas in the lower gastrointestinal tract and less frequently, the upper gastrointestinal tract. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas ...

Last Updated: 29 Nov 2011

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Hepatocelluar carcinoma associated with attenuated familial adenomatous polyposis: a case report and review of the literature.
 

Author(s): Mingqing Li, David A Gerber, Mark Koruda, Bert H O'Neil

Journal: Clin Colorectal Cancer. 2012 Mar;11(1):77-81.

 

Last Updated: 7 Feb 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 7 Apr 2014

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Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis
 

Status: Recruiting

Condition Summary: FAP-Familial Adenomatous Polyposis

 

Last Updated: 25 Jun 2014

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Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 3 Aug 2011

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