Familial Polyposis

Common Name(s)

Familial Polyposis

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Polyposis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Polyposis" returned 352 free, full-text research articles on human participants. First 3 results:

Upper GI tract lesions in familial adenomatous polyposis (FAP): enrichment of pyloric gland adenomas and other gastric and duodenal neoplasms.
 

Author(s): Laura D Wood, Safia N Salaria, Michael W Cruise, Francis M Giardiello, Elizabeth A Montgomery

Journal: Am. J. Surg. Pathol.. 2014 Mar;38(3):389-93.

 

Patients with familial adenomatous polyposis (FAP), an autosomal dominant cancer predisposition syndrome caused by mutations in the APC gene, develop neoplasms in both the upper and lower gastrointestinal (GI) tract. To clarify the upper GI tract lesions in FAP patients in a tertiary ...

Last Updated: 14 Feb 2014

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A novel germline mutation in exon 10 of the SMAD4 gene in a familial juvenile polyposis.
 

Author(s): Myung Jin Jee, Soon Man Yoon, Eui Joong Kim, Hyun-Jung Choi, Jong-Won Kim, Ro Hyun Sung, Joung Ho Han, Hee Bok Chae, Seon Mee Park, Sei Jin Youn

Journal: Gut Liver. 2013 Nov;7(6):747-51.

 

Familial juvenile polyposis (FJP) is a rare autosomal dominant hereditary disorder that is characterized by the development of multiple distinct juvenile polyps in the gastrointestinal tract and an increased risk of cancer. Recently, germline mutations, including mutations in the ...

Last Updated: 6 Dec 2013

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Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls.
 

Author(s): Bjorn W H van Heumen, Hennie M J Roelofs, René H M te Morsche, Fokko M Nagengast, Wilbert H M Peters

Journal:

 

Familial adenomatous polyposis (FAP) is a disease characterized by the development of hundreds to thousands of adenomatous polyps in the colorectum early in life. Virtually all patients with FAP will develop colorectal cancer before the age of 40 to 50 years, unless prophylactic colectomy ...

Last Updated: 9 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Polyposis" returned 27 free, full-text review articles on human participants. First 3 results:

Risk of ileal pouch neoplasms in patients with familial adenomatous polyposis.
 

Author(s): Masahiro Tajika, Yasumasa Niwa, Vikram Bhatia, Tsutomu Tanaka, Makoto Ishihara, Kenji Yamao

Journal: World J. Gastroenterol.. 2013 Oct;19(40):6774-83.

 

Restorative proctocolectomy is the most common surgical option for patients with familial adenomatous polyposis (FAP). However, adenomas may develop in the ileal pouch mucosa over time, and even carcinoma in the pouch has been reported. We therefore reviewed the prevalence, nature, ...

Last Updated: 4 Nov 2013

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APC germline mutations in individuals being evaluated for familial adenomatous polyposis: a review of the Mayo Clinic experience with 1591 consecutive tests.
 

Author(s): Sarah E Kerr, Cheryl B Thomas, Stephen N Thibodeau, Matthew J Ferber, Kevin C Halling

Journal: J Mol Diagn. 2013 Jan;15(1):31-43.

 

Inactivating APC mutations cause familial adenomatous polyposis, classically characterized by hundreds to thousands of adenomatous colorectal polyps and cancer. Historically, 98% of pathogenic alterations in APC are nonsense or frameshift mutations; however, few reported series have ...

Last Updated: 24 Dec 2012

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Chemoprevention in familial adenomatous polyposis.
 

Author(s): Brian Kim, Francis M Giardiello

Journal: Best Pract Res Clin Gastroenterol. 2011 Aug;25(4-5):607-22.

 

Familial adenomatous polyposis (FAP) predictably leads to adenomas and eventual adenocarcinomas in the lower gastrointestinal tract and less frequently, the upper gastrointestinal tract. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas ...

Last Updated: 29 Nov 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 3 Dec 2014

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Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 7 Oct 2014

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Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis
 

Status: Recruiting

Condition Summary: FAP-Familial Adenomatous Polyposis

 

Last Updated: 25 Jun 2014

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