Familial Polyposis

Common Name(s)

Familial Polyposis

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Polyposis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Polyposis" returned 361 free, full-text research articles on human participants. First 3 results:

Congenital hypertrophy of retinal pigment epithelium (CHRPE) in patients with familial adenomatous polyposis (FAP); a polyposis registry experience.
 

Author(s): Anwer Nusliha, Ushantha Dalpatadu, Binara Amarasinghe, Pramodh Chitral Chandrasinghe, Kemal Ismail Deen

Journal:

 

Familial Adenomatous Polyposis (FAP) is an autosomal dominant condition giving rise to multiple adenomatous polyps in the colon which invariably become malignant by the fourth decade. Congenital hypertrophy of retinal pigment epithelium (CHRPE) is one of its extra intestinal manifestations ...

Last Updated: 22 Oct 2014

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A large deletion of chromosome 5q22.1-22.2 associated with sparse type of familial adenomatous polyposis: report of a case.
 

Author(s): Tatsuro Yamaguchi, Koichi Koizumi, Masami Arai, Kazuo Tamura, Takeru Iijima, Shin-Ichiro Horiguchi, Michiko Miyaki

Journal: Jpn. J. Clin. Oncol.. 2014 Dec;44(12):1243-7.

 

The proband was a 32-year-old man with sparse type of familial adenomatous polyposis with fundic gland and duodenal polyps and congenital hypertrophy of the retinal pigment epithelium without osteoma, dental abnormalities and desmoid tumors. Direct DNA sequencing did not detect germline ...

Last Updated: 26 Nov 2014

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Evaluation of endoscopic characteristics of upper gastrointestinal polyps in patients with familial adenomatous polyposis.
 

Author(s): Seyed Reza Fatemi, Azadeh Safaee, Sara Pasha, Mohamad Amin Pourhoseingholi, Rasool Bahrainei, Mahsa Molaei

Journal: Asian Pac. J. Cancer Prev.. 2014 ;15(16):6945-8.

 

Familial adenomatous polyposis (FAP) is a disease inherited in an autosomal dominant fashion. Most FAP patients develop upper gastrointestinal polyps; especially those in the antrum and duodenum are usually neoplastic. The aim of this study was to evaluate the prevalence of gastroduodenal ...

Last Updated: 29 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Polyposis" returned 27 free, full-text review articles on human participants. First 3 results:

Risk of ileal pouch neoplasms in patients with familial adenomatous polyposis.
 

Author(s): Masahiro Tajika, Yasumasa Niwa, Vikram Bhatia, Tsutomu Tanaka, Makoto Ishihara, Kenji Yamao

Journal: World J. Gastroenterol.. 2013 Oct;19(40):6774-83.

 

Restorative proctocolectomy is the most common surgical option for patients with familial adenomatous polyposis (FAP). However, adenomas may develop in the ileal pouch mucosa over time, and even carcinoma in the pouch has been reported. We therefore reviewed the prevalence, nature, ...

Last Updated: 4 Nov 2013

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APC germline mutations in individuals being evaluated for familial adenomatous polyposis: a review of the Mayo Clinic experience with 1591 consecutive tests.
 

Author(s): Sarah E Kerr, Cheryl B Thomas, Stephen N Thibodeau, Matthew J Ferber, Kevin C Halling

Journal: J Mol Diagn. 2013 Jan;15(1):31-43.

 

Inactivating APC mutations cause familial adenomatous polyposis, classically characterized by hundreds to thousands of adenomatous colorectal polyps and cancer. Historically, 98% of pathogenic alterations in APC are nonsense or frameshift mutations; however, few reported series have ...

Last Updated: 24 Dec 2012

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Chemoprevention in familial adenomatous polyposis.
 

Author(s): Brian Kim, Francis M Giardiello

Journal: Best Pract Res Clin Gastroenterol. 2011 Aug;25(4-5):607-22.

 

Familial adenomatous polyposis (FAP) predictably leads to adenomas and eventual adenocarcinomas in the lower gastrointestinal tract and less frequently, the upper gastrointestinal tract. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas ...

Last Updated: 29 Nov 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 3 Dec 2014

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Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 24 Jun 2015

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Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis
 

Status: Recruiting

Condition Summary: FAP-Familial Adenomatous Polyposis

 

Last Updated: 25 Jun 2014

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