Familial Hypertrophic Cardiomyopathy

Common Name(s)

Familial Hypertrophic Cardiomyopathy

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Hypertrophic Cardiomyopathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Hypertrophic Cardiomyopathy" returned 137 free, full-text research articles on human participants. First 3 results:

Asymmetric left ventricular hypertrophy associated with morbid obesity mimicking familial hypertrophic cardiomyopathy.
 

Author(s): Raymond Ching-Chiew Wong, Kong Bing Tan

Journal: Singapore Med J. 2014 Dec;55(12):e201-4.

 

Asymmetric septal hypertrophy with systolic anterior motion of the mitral valve is frequently a phenotypic, but not pathognomonic, expression of genetic hypertrophic cardiomyopathy (HCM) with or without obstruction. It can, however, be associated nonspecifically with other forms of ...

Last Updated: 29 Jan 2015

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Impact of familial hypertrophic cardiomyopathy-linked mutations in the NH2 terminus of the RLC on β-myosin cross-bridge mechanics.
 

Author(s): Gerrie P Farman, Priya Muthu, Katarzyna Kazmierczak, Danuta Szczesna-Cordary, Jeffrey R Moore

Journal: J. Appl. Physiol.. 2014 Dec;117(12):1471-7.

 

Familial hypertrophic cardiomyopathy (HCM) is associated with mutations in sarcomeric proteins, including the myosin regulatory light chain (RLC). Here we studied the impact of three HCM mutations located in the NH2 terminus of the RLC on the molecular mechanism of β-myosin heavy ...

Last Updated: 16 Dec 2014

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Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells.
 

Author(s): Lu Han, Yang Li, Jason Tchao, Aaron D Kaplan, Bo Lin, You Li, Jocelyn Mich-Basso, Agnieszka Lis, Narmeen Hassan, Barry London, Glenna C L Bett, Kimimasa Tobita, Randall L Rasmusson, Lei Yang

Journal: Cardiovasc. Res.. 2014 Nov;104(2):258-69.

 

Familial hypertrophic cardiomyopathy (HCM) is one the most common heart disorders, with gene mutations in the cardiac sarcomere. Studying HCM with patient-specific induced pluripotent stem-cell (iPSC)-derived cardiomyocytes (CMs) would benefit the understanding of HCM mechanism, as ...

Last Updated: 1 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Hypertrophic Cardiomyopathy" returned 7 free, full-text review articles on human participants. First 3 results:

Multi-scale computational models of familial hypertrophic cardiomyopathy: genotype to phenotype.
 

Author(s): Stuart G Campbell, Andrew D McCulloch

Journal: J R Soc Interface. 2011 Nov;8(64):1550-61.

 

Familial hypertrophic cardiomyopathy (FHC) is an inherited disorder affecting roughly one in 500 people. Its hallmark is abnormal thickening of the ventricular wall, leading to serious complications that include heart failure and sudden cardiac death. Treatment is complicated by variation ...

Last Updated: 28 Sep 2011

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[Malignant form of familial hypertrophic cardiomyopathy complicated with ventricular fibrillation in siblings. Electrocardiogram in hypertrophic cardiomyopathy - a review].
 

Author(s): Piotr Kukla, Paweł Petkow-Dimitrow, Marek Jastrzebski, Jacek Bednarek, Jacek Lelakowski, Leszek Bryniarski

Journal: Kardiol Pol. 2009 Jul;67(7):774-80; discussion 781.

 

A family with hypertrophic cardiomyopathy (HCM) (15-year-old boy, his 17-year-old sister and 45-year-old father) is described. The first sign of HCM was cardiac arrest (CA) due to ventricular fibrillation (VF) in a boy. A few months later sister of proband had the episode of CA due ...

Last Updated: 3 Aug 2009

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Myosin binding protein C: structural abnormalities in familial hypertrophic cardiomyopathy.
 

Author(s): Cecily E Oakley, Brett D Hambly, Paul M G Curmi, Louise J Brown

Journal: Cell Res.. 2004 Apr;14(2):95-110.

 

The muscle protein myosin binding protein C (MyBPC) is a large multi-domain protein whose role in the sarcomere is complex and not yet fully understood. Mutations in MyBPC are strongly associated with the heart disease familial hypertrophic cardiomyopathy (FHC) and these experiments ...

Last Updated: 29 Apr 2004

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy
 

Status: Recruiting

Condition Summary: Hypertrophic Cardiomyopathy

 

Last Updated: 11 Jul 2016

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Congenital Muscle Disease Study of Patient and Family Reported Medical Information
 

Status: Recruiting

Condition Summary: Muscular Dystrophy; Congenital Muscular Dystrophy; Fukutin-related Protein Gene; Limb Girdle; FKRP Gene; Childhood Onset LGMD; Adult Onset LGMD; POMT1; POMT2; POMGnT1; LARGE; Alpha Dystroglycan; Dystroglycanopathy; Centronuclear; Multiminicore; Multicore; Minicore; Congenital Fiber Type Disproportion; Myotubular; Nemaline; Congenital Myopathy; Neuromuscular; Rigid Spine; Phenotype-Genotype Correlation; Cough Assisted Device; Neuromuscular Disease; Respiratory Exacerbation; Invasive Ventilation; Chest Physiotherapy; Congenital Myopathies; Genetic Mutations; Hypertrophic Cardiomyopathy; Wheelchair Use; Cataract; Opthalmoplegia; Ullrich Congenital Muscular Dystrophy; Intermediate Collagen VI Myopathy; Laminin Alpha 2 Related Congenital Muscular Dystrophy; MDC1A; Merosin Deficient Congenital Muscular Dystrophy; Congenital Muscular Dystrophy Undiagnosed; Congenital Muscular Dystrophy Merosin Positive; Walker Warburg Syndrome; Muscle Eye Brain Disease; Fukuyama; Integrin Alpha 7 Deficiency; Integrin Alpha 9 Deficiency; Laminopathy; Lamin AC; SEPN 1 Related Myopathies; Bethlem Myopathy; Dystroglycanopathies; LGMD2K; LGMD2I; LGMD2L; LGMD2N; Actin Aggregation Myopathy; Cap Disease; Central Core Disease; Centronuclear Myopathy; Core Rod Myopathy; Hyaline Body Myopathy; Multiminicore Myopathy; Myotubular Myopathy; Nemaline Myopathy; Tubular Aggregate Myopathy; Zebra Body Disease Myopathy; Congenital Myopathy Other; Reducing Body Myopathy; Sarcotubular Myopathy; Spheroid Body Myopathy

 

Last Updated: 5 Oct 2015

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Compassionate Use of Triheptanoin (C7) for Fatty Acid Oxidation Disorders and Glycogen Storage Disease
 

Status: Available

Condition Summary: Very Long-chain acylCoA Dehydrogenase (VLCAD) Deficiency; Carnitine Palmitoyltransferase Deficiencies (CPT1, CPT2); Mitochondrial Trifunctional Protein Deficiency; Long-chain Hydroxyacyl-CoA Dehydrogenase Deficiency; Glycogen Storage Disorders; Pyruvate Carboxylase Deficiency Disease; ACYL-CoA DEHYDROGENASE FAMILY, MEMBER 9, DEFICIENCY of

 

Last Updated: 3 Dec 2015

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