Familial Dilated Cardiomyopathy

Common Name(s)

Familial Dilated Cardiomyopathy

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Dilated Cardiomyopathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Dilated Cardiomyopathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Dilated Cardiomyopathy" returned 72 free, full-text research articles on human participants. First 3 results:

Establishing disease causality for a novel gene variant in familial dilated cardiomyopathy using a functional in-vitro assay of regulated thin filaments and human cardiac myosin.
 

Author(s): Stephen Pan, Ruth F Sommese, Karim I Sallam, Suman Nag, Shirley Sutton, Susan M Miller, James A Spudich, Kathleen M Ruppel, Euan A Ashley

Journal:

 

As next generation sequencing for the genetic diagnosis of cardiovascular disorders becomes more widely used, establishing causality for putative disease causing variants becomes increasingly relevant. Diseases of the cardiac sarcomere provide a particular challenge in this regard ...

Last Updated: 27 Oct 2015

Go To URL
TBX5 loss-of-function mutation contributes to familial dilated cardiomyopathy.
 

Author(s): Xian-Ling Zhang, Xing-Biao Qiu, Fang Yuan, Juan Wang, Cui-Mei Zhao, Ruo-Gu Li, Lei Xu, Ying-Jia Xu, Hong-Yu Shi, Xu-Min Hou, Xin-Kai Qu, Ya-Wei Xu, Yi-Qing Yang

Journal: Biochem. Biophys. Res. Commun.. 2015 Mar;459(1):166-71.

 

The cardiac T-box transcription factor TBX5 is crucial for proper cardiovascular development, and mutations in TBX5 have been associated with various congenital heart diseases and arrhythmias in humans. However, whether mutated TBX5 contributes to dilated cardiomyopathy (DCM) remains ...

Last Updated: 17 Mar 2015

Go To URL
Prognostic implications of the systolic to diastolic duration ratio in children with idiopathic or familial dilated cardiomyopathy.
 

Author(s): Tapas Mondal, Cameron Slorach, Cedric Manlhiot, Wei Hui, Paul F Kantor, Brian W McCrindle, Luc Mertens, Mark K Friedberg

Journal: Circ Cardiovasc Imaging. 2014 Sep;7(5):773-80.

 

Childhood dilated cardiomyopathy (DCM) carries high morbidity and mortality. The echocardiographic systolic to diastolic (S:D) duration ratio, an indicator of global cardiac performance, is elevated in DCM; however, its prognostic implications have not been investigated in this population.

Last Updated: 17 Sep 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Dilated Cardiomyopathy" returned 7 free, full-text review articles on human participants. First 3 results:

Update 2011: clinical and genetic issues in familial dilated cardiomyopathy.
 

Author(s): Ray E Hershberger, Jill D Siegfried

Journal: J. Am. Coll. Cardiol.. 2011 Apr;57(16):1641-9.

 

A great deal of progress has recently been made in the discovery and understanding of the genetics of familial dilated cardiomyopathy (FDC). A consensus has emerged that with a new diagnosis of idiopathic dilated cardiomyopathy (IDC), the clinical screening of first-degree family ...

Last Updated: 15 Apr 2011

Go To URL
Cardiomyopathy, familial dilated.
 

Author(s): Matthew R G Taylor, Elisa Carniel, Luisa Mestroni

Journal:

 

Dilated cardiomyopathy (DCM) is a heart muscle disease characterized by ventricular dilatation and impaired systolic function. Patients with DCM suffer from heart failure, arrhythmia, and are at risk of premature death. DCM has a prevalence of one case out of 2500 individuals with ...

Last Updated: 4 Sep 2006

Go To URL
Clinical and genetic issues in familial dilated cardiomyopathy.
 

Author(s): Emily L Burkett, Ray E Hershberger

Journal: J. Am. Coll. Cardiol.. 2005 Apr;45(7):969-81.

 

Idiopathic dilated cardiomyopathy (IDC) is characterized by left ventricular dilatation and systolic dysfunction after known causes have been excluded. Idiopathic dilated cardiomyopathy occurring in families, or familial dilated cardiomyopathy (FDC), may occur in 20% to 50% of IDC ...

Last Updated: 5 Apr 2005

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

PREclinical Mutation CARriers From Families With DIlated Cardiomyopathy and ACE Inhibitors
 

Status: Recruiting

Condition Summary: Dilated Cardiomyopathy

 

Last Updated: 19 Apr 2012

Go to URL