Familial Dilated Cardiomyopathy

Common Name(s)

Familial Dilated Cardiomyopathy

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Dilated Cardiomyopathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Dilated Cardiomyopathy" returned 78 free, full-text research articles on human participants. First 3 results:

Whole exome sequencing identifies a KCNJ12 mutation as a cause of familial dilated cardiomyopathy.
 

Author(s): Hai-Xin Yuan, Kai Yan, Dong-Yan Hou, Zhi-Yong Zhang, Hua Wang, Xin Wang, Juan Zhang, Xiao-Rong Xu, Yan-Hong Liang, Wen-Shu Zhao, Lin Xu, Lin Zhang

Journal: Medicine (Baltimore). 2017 Aug;96(33):e7727.

 

Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation, and is associated with systolic dysfunction and increased action potential duration. Approximately 50% of DCM cases are caused by inherited gene mutations with genetic and phenotypic heterogeneity. Next generation ...

Last Updated: 17 Aug 2017

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Altered myocyte contractility and calcium homeostasis in alpha-myosin heavy chain point mutations linked to familial dilated cardiomyopathy.
 

Author(s): Matthew Klos, Lakshmi Mundada, Indroneal Banerjee, Sherry Morgenstern, Stephanie Myers, Michael Leone, Mark Kleid, Todd Herron, Eric Devaney

Journal: Arch. Biochem. Biophys.. 2017 Feb;615():53-60.

 

Mutations in the human cardiac motor protein beta-myosin heavy chain (βMHC) have been long recognized as a cause of familial hypertrophic cardiomyopathy. Recently, mutations (P830L and A1004S) in the less abundant but faster isoform alpha-myosin heavy chain (αMHC) have been linked ...

Last Updated: 15 Jan 2017

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Familial Dilated Cardiomyopathy Caused by a Novel Frameshift in the BAG3 Gene.
 

Author(s): Rocio Toro, Alexandra Pérez-Serra, Oscar Campuzano, Javier Moncayo-Arlandi, Catarina Allegue, Anna Iglesias, Alipio Mangas, Ramon Brugada

Journal:

 

Dilated cardiomyopathy, a major cause of chronic heart failure and cardiac transplantation, is characterized by left ventricular or biventricular heart dilatation. In nearly 50% of cases the pathology is inherited, and more than 60 genes have been reported as disease-causing. However, ...

Last Updated: 9 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Dilated Cardiomyopathy" returned 7 free, full-text review articles on human participants. First 3 results:

Genetic Variations Leading to Familial Dilated Cardiomyopathy.
 

Author(s): Kae Won Cho, Jongsung Lee, Youngjo Kim

Journal: Mol. Cells. 2016 Oct;39(10):722-727.

 

Cardiomyopathy is a major cause of death worldwide. Based on pathohistological abnormalities and clinical manifestation, cardiomyopathies are categorized into several groups: hypertrophic, dilated, restricted, arrhythmogenic right ventricular, and unclassified. Dilated cardiomyopathy, ...

Last Updated: 1 Nov 2016

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Update 2011: clinical and genetic issues in familial dilated cardiomyopathy.
 

Author(s): Ray E Hershberger, Jill D Siegfried

Journal: J. Am. Coll. Cardiol.. 2011 Apr;57(16):1641-9.

 

A great deal of progress has recently been made in the discovery and understanding of the genetics of familial dilated cardiomyopathy (FDC). A consensus has emerged that with a new diagnosis of idiopathic dilated cardiomyopathy (IDC), the clinical screening of first-degree family ...

Last Updated: 15 Apr 2011

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Cardiomyopathy, familial dilated.
 

Author(s): Matthew R G Taylor, Elisa Carniel, Luisa Mestroni

Journal:

 

Dilated cardiomyopathy (DCM) is a heart muscle disease characterized by ventricular dilatation and impaired systolic function. Patients with DCM suffer from heart failure, arrhythmia, and are at risk of premature death. DCM has a prevalence of one case out of 2500 individuals with ...

Last Updated: 4 Sep 2006

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.