Familial Aortic Dissection

Common Name(s)

Familial Aortic Dissection

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Aortic Dissection" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Aortic Dissection" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Aortic Dissection" returned 6 free, full-text research articles on human participants. First 3 results:

Exome sequencing identifies SMAD3 mutations as a cause of familial thoracic aortic aneurysm and dissection with intracranial and other arterial aneurysms.
 

Author(s): Ellen S Regalado, Dong-Chuan Guo, Carlos Villamizar, Nili Avidan, Dawna Gilchrist, Barbara McGillivray, Lorne Clarke, Francois Bernier, Regie L Santos-Cortez, Suzanne M Leal, Aida M Bertoli-Avella, Jay Shendure, Mark J Rieder, Deborah A Nickerson, , Dianna M Milewicz

Journal: Circ. Res.. 2011 Sep;109(6):680-6.

 

Thoracic aortic aneurysms leading to acute aortic dissections (TAAD) can be inherited in families in an autosomal dominant manner. As part of the spectrum of clinical heterogeneity of familial TAAD, we recently described families with multiple members that had TAAD and intracranial ...

Last Updated: 2 Sep 2011

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Familial thoracic aortic aneurysms and dissections: identification of a novel locus for stable aneurysms with a low risk for progression to aortic dissection.
 

Author(s): Dong-Chuan Guo, Ellen S Regalado, Charles Minn, Van Tran-Fadulu, Joshua Coney, Jiumei Cao, Min Wang, Robert K Yu, Anthony L Estrera, Hazim J Safi, Sanjay S Shete, Dianna M Milewicz

Journal: Circ Cardiovasc Genet. 2011 Feb;4(1):36-42.

 

Thoracic aortic aneurysms leading to acute aortic dissections are the major diseases that affect the thoracic aorta. Approximately 20% of patients with thoracic aortic aneurysms and dissections (TAAD) have a family history of TAAD, and these patients present younger with more rapidly ...

Last Updated: 17 Feb 2011

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Familial thoracic aortic aneurysm and dissection associated with Marfan-related gene mutations: case report of a family with two gene mutations.
 

Author(s): Tohru Yamawaki, Kazuhiro Nagaoka, Kunio Morishige, Kenji Sadamatsu, Hideki Tashiro, Hiroshi Yasunaga, Hiroko Morisaki, Takayuki Morisaki

Journal: Intern. Med.. 2009 ;48(7):555-8.

 

We report three cases of thoracic aortic aneurysm and dissection in a Japanese family. Marfan-related genes were analyzed; FBN1 and TGFBR2 gene mutations were observed in this family.

Last Updated: 1 Apr 2009

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Aortic Dissection" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm
 

Status: Recruiting

Condition Summary: Thoracic Aortic Aneurysm

 

Last Updated: 3 Nov 2016

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