Fallopian Tube Cancer

Common Name(s)

Fallopian Tube Cancer

Fallopian tube cancer is a very rare form of cancer with only 1,500 to 2,000 cases reported each year in the United States. However, a number of cancers start in other parts of the body and spread to the fallopian tubes, called secondary fallopian tube cancers. Some symptoms include abnormal vaginal bleeding, abnormal vaginal discharge, abdominal pain, and feeling a mass in the abdomen (belly) or pelvis. A female pelvic exam can assist in the diagnosis of this condition by evaluating the size and shape of the uterus, vagina, ovaries, fallopian tubes, bladder and rectum. A blood test can also be performed to check the levels of a certain protein called CA125, which may be used to diagnose fallopian tube cancer. Treatment usually involves surgery and chemotherapy, depending on age, desire to have children, and the type and stage of the tumor.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fallopian Tube Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fallopian Tube Cancer" returned 39 free, full-text research articles on human participants. First 3 results:

Independent radiologic review of the Gynecologic Oncology Group Study 0218, a phase III trial of bevacizumab in the primary treatment of advanced epithelial ovarian, primary peritoneal, or fallopian tube cancer.
 

Author(s): Robert A Burger, Mark F Brady, Joon Rhee, Mika A Sovak, George Kong, Hoa P Nguyen, Michael A Bookman

Journal: Gynecol. Oncol.. 2013 Oct;131(1):21-6.

 

Gynecologic Oncology Group Study 0218 (GOG-0218), a phase III, placebo-controlled trial in newly diagnosed stage III/IV ovarian cancer (OC), demonstrated a benefit in investigator (INV)-assessed progression-free survival (PFS) with bevacizumab (BEV) administered with and following ...

Last Updated: 7 Oct 2013

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Gene expression analyses support fallopian tube epithelium as the cell of origin of epithelial ovarian cancer.
 

Author(s): Daniel J O'Shannessy, Stephen M Jackson, Natalie C Twine, Bryan E Hoffman, Zoltan Dezso, Sergei I Agoulnik, Elizabeth B Somers

Journal:

 

Folate receptor alpha (FOLR1/FRA) is reported to be overexpressed in epithelial ovarian cancers (EOC), especially the serous histotype. Further, while dysregulation of the folate-dependent 1-carbon cycle has been implicated in tumorogenesis, little is known relative to the potential ...

Last Updated: 24 Jul 2013

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Early detection of ovarian and fallopian tube cancer by examination of cytological samples from the endometrial cavity.
 

Author(s): I Otsuka, S Kameda, K Hoshi

Journal: Br. J. Cancer. 2013 Aug;109(3):603-9.

 

Accumulating evidence suggests that many ovarian high-grade serous carcinomas (HGSCs) originate in the fallopian tube. Malignant cells shed by tubal lesions can be detected by examination of cytological samples from the endometrial cavity (endometrial cytological testing). To evaluate ...

Last Updated: 7 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fallopian Tube Cancer" returned 2 free, full-text review articles on human participants. First 3 results:

The role of the fallopian tube in the origin of ovarian cancer.
 

Author(s): Britt K Erickson, Michael G Conner, Charles N Landen

Journal: Am. J. Obstet. Gynecol.. 2013 Nov;209(5):409-14.

 

Advanced cases of epithelial ovarian, primary peritoneal, and primary tubal malignancies have a relatively poor prognosis and collectively remain the most deadly of all gynecologic malignancies. Although traditionally thought of as one disease process, ongoing research suggests that ...

Last Updated: 11 Nov 2013

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Intercepting pelvic cancer in the distal fallopian tube: theories and realities.
 

Author(s): Christopher P Crum

Journal: Mol Oncol. 2009 Apr;3(2):165-70.

 

The pathogenesis of high-grade serous carcinoma of the ovary has come into sharper focus as closer attention has been paid to the earlier phases of this disease. The study of patients with BRCA mutation has been of particular value, in as much as the examination of prophylactic salpingo-oophorectomies ...

Last Updated: 22 Apr 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer
 

Status: Recruiting

Condition Summary: Recurrent Fallopian Tube Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Primary Peritoneal Cavity Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Epithelial Cancer; Stage IV Primary Peritoneal Cavity Cancer

 

Last Updated: 15 Nov 2014

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Study of RAD001 and Bevacizumab in Recurrent Ovarian, Peritoneal, and Fallopian Tube Cancer
 

Status: Recruiting

Condition Summary: Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer

 

Last Updated: 13 Mar 2013

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Phase 2 Trial of Regorafenib in Patients With Recurrent Ovarian, Primary Peritoneal and Fallopian Tube Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Cancer; Primary Peritoneal Cancer; Fallopian Tube Cancer

 

Last Updated: 28 Oct 2014

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