Factor X Deficiency

Common Name(s)

Factor X Deficiency

Factor X deficiency is a rare autosomal recessive bleeding disorder showing variable phenotypic severity. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. The disorder can be caused either by reduced levels of the factor X protein or by synthesis of a dysfunctional factor X protein (summary by {31:Millar et al., 2000}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Factor X Deficiency" for support, advocacy or research.

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The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

Last Updated: 3 Apr 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Factor X Deficiency" for support, advocacy or research.

Logo
The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

http://www.haemophilia.org.uk/

Last Updated: 3 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Factor X Deficiency" returned 42 free, full-text research articles on human participants. First 3 results:

Factor X Deficiency with Heterozygous Mutations of Novel p.G435S and Known p.G244R in a Patient Presenting with Severe Umbilical Hemorrhage.
 

Author(s): Yoko Matsuo, Tatsuki Mizuochi, Mitsuo Miho, Shinichiro Nakagawa, Shuichi Ozono, Koichiro Ueda, Yoko Sogabe, Ritsuko Seki, Kenji Soejima, Takashi Okamura, Yushiro Yamashita

Journal: Kurume Med J. 2017 Apr;63(1.2):23-28.

 

A 10-day-old male patient was referred to our hospital with severe umbilical bleeding. Prothrombin time (PT) and activated partial thromboplastin time (APTT) were prominently prolonged. Plasma coagulation factor X (FX) activity and antigen levels were 1% and 0.6%, respectively. A ...

Last Updated: 17 Mar 2017

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Rare post-operative complications in a previously undiagnosed Congenital Factor X deficiency patient.
 

Author(s): H Mohd Nazri, A A Suhair, W A R Wan Suriana, Z Zefarina, H Azlan, A Wan Zaidah

Journal: Malays J Pathol. 2016 Dec;38(3):327-331.

 

Factor X (FX) deficiency is a rare autosomal recessive congenital bleeding disorder. The clinical presentation is among the most severe among the rare coagulation defects. Thus, majority of diagnosed patients will receive factor replacement therapy before surgical manipulation. However, ...

Last Updated: 28 Dec 2016

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[Isolated factor X deficiency in chronic myelomonocytic leukemia: Report of one case].
 

Author(s): Javier Zelada, Gabriela Cantó, Alejandro Berkovits, Gonzalo Diocares, Adriana López

Journal: Rev Med Chil. 2015 Nov;143(11):1490-3.

 

Bleeding disorders are commonly associated with hemato-oncologic diseases. We report a 68 years old male with a chronic myelomonocytic leukemia derived from a long lasting mielodysplastic syndrome that did not respond to treatment with Azacitidine. The patient was hospitalized due ...

Last Updated: 13 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Factor X Deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Jul 2017

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