Factor VII Deficiency

Common Name(s)

Factor VII Deficiency

Factor VII deficiency is an autosomal recessive bleeding disorder showing variable severity (summary by {22:Millar et al., 2000}). {23:Perry (2002)} provided a comprehensive review of factor VII deficiency with a description of F7 polymorphisms, gene structure, and a summary of 120 mutations.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Factor VII Deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Factor VII Deficiency" returned 43 free, full-text research articles on human participants. First 3 results:

Prophylaxis in congenital factor VII deficiency: indications, efficacy and safety. Results from the Seven Treatment Evaluation Registry (STER).
 

Author(s): Mariasanta Napolitano, Muriel Giansily-Blaizot, Alberto Dolce, Jean F Schved, Guenter Auerswald, Jørgen Ingerslev, Jens Bjerre, Carmen Altisent, Pimlak Charoenkwan, Lisa Michaels, Ampaiwan Chuansumrit, Giovanni Di Minno, Umran Caliskan, Guglielmo Mariani

Journal: Haematologica. 2013 Apr;98(4):538-44.

 

Because of the very short half-life of factor VII, prophylaxis in factor VII deficiency is considered a difficult endeavor. The clinical efficacy and safety of prophylactic regimens, and indications for their use, were evaluated in factor VII-deficient patients in the Seven Treatment ...

Last Updated: 1 Apr 2013

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Long-term successful percutaneous coronary intervention in factor VII deficiency.
 

Author(s): Jose Antonio Linares Vicente, Jorge Ondiviela Pérez, Rosa Cornudella Lacasa

Journal: J Invasive Cardiol. 2012 Jun;24(6):E119-21.

 

Factor VII deficiency (FVIId) is a congenital coagulation disorder with a wide spectrum of bleeding phenotypes. Percutaneous coronary intervention requires full anticoagulation during stent implantation to avoid acute coronary thrombosis and long-term dual antiplatelet therapy. Feasibility ...

Last Updated: 11 Jun 2012

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[Gene analysis of a combined inherited factor VII and factor X deficiency pedigree].
 

Author(s): Ming-shan Wang, Yan-hui Jin, Fang-xiu Zheng, Hai-xiao Xie, Peng-fei Xu, Zhen-zhen Niu

Journal: Zhonghua Xue Ye Xue Za Zhi. 2011 Dec;32(12):854-7.

 

To perform gene analysis and family survey of a patient with combined inherited FVII and FX deficiency, and to identify the gene mutation of this patient.

Last Updated: 20 Feb 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Factor VII Deficiency" returned 2 free, full-text review articles on human participants. First 3 results:

Is prophylaxis required for delivery in women with factor VII deficiency?
 

Author(s): L M Baumann Kreuziger, Colleen T Morton, Mark T Reding

Journal: Haemophilia. 2013 Nov;19(6):827-32.

 

Factor VII (fVII) deficiency is a rare congenital bleeding disorder in which fVII activity level and bleeding tendency do not completely correlate. Pregnancy and delivery present a significant haemostatic challenge to women with fVII deficiency. Treatment with recombinant factor VIIa ...

Last Updated: 29 Oct 2013

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Factor VII deficiency and developmental abnormalities in a patient with partial monosomy of 13q and trisomy of 16p: case report and review of the literature.
 

Author(s): Brian P Brooks, Jeanne M Meck, Bassem R Haddad, Claude Bendavid, Delphine Blain, Jeffrey A Toretsky

Journal:

 

Unbalanced chromosomal translocations may present with a variety of clinical and laboratory findings and provide insight into the functions of genes on the involved chromosomal segments.

Last Updated: 23 Feb 2006

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.