Factor V Deficiency

Common Name(s)

Factor V Deficiency

Factor V deficiency is an inherited blood disorder that involves abnormal blood clotting (coagulation). This disorder is caused by the deficiency of a blood protein called factor V. The reduced amount of factor V leads to episodes of abnormal bleeding that range from mild to severe.  Factor V deficiency is inherited in an autosomal recessive manner, which means that both copies of the F5 gene in each cell have mutations.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Factor V Deficiency" for support, advocacy or research.

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The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

Last Updated: 3 Apr 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Factor V Deficiency" for support, advocacy or research.

Logo
The Haemophilia Society

To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders.

http://www.haemophilia.org.uk/

Last Updated: 3 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Factor V Deficiency" returned 67 free, full-text research articles on human participants. First 3 results:

Factor V Deficiency in Korean Patients: Clinical and Laboratory Features, Treatment, and Outcome.
 

Author(s): Young Hoon Park, Joo Han Lim, Hyeon Gyu Yi, Moon Hee Lee, Chul Soo Kim

Journal: J. Korean Med. Sci.. 2016 Feb;31(2):208-13.

 

Due to rarity of factor V (FV) deficiency, there have been only a few case reports in Korea. We retrospectively analysed the clinical-laboratory features of FV deficiency in 10 Korean patients. Between January 1987 and December 2013, 10 case reports published in a Korean journal or ...

Last Updated: 3 Feb 2016

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Genetic Confirmation of Congenital Factor V Deficiency in Korean Patients.
 

Author(s): Chang-Hun Park, Kiyoung Yoo, Ki-O Lee, Sun-Hee Kim, Ki-Woong Sung, Hee-Jin Kim

Journal: Ann Lab Med. 2016 Mar;36(2):182-4.

 

Last Updated: 28 Dec 2015

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Successful Living-Related Renal Allograft in a Recipient With Factor V Leiden Deficiency: A Case Report.
 

Author(s): Evangelia Florou, Maria Koukoulaki, Theodoridis Theodoros, Vasileios Kalatzis, Vasileios Vougas, Elissavet Stamataki, Vasiliki Christopoulou Kokkinou, Alkiviadis Kostakis, Spiros Drakopoulos

Journal: Exp Clin Transplant. 2017 Feb;15(1):96-99.

 

Thrombophilia due to activated protein C resistance (Leiden mutation) is the most common inherited thrombophilic disorder with 5% incidence in whites. Renal transplant of these patients entails a risk of vascular thrombosis soon after the transplant; and acute rejection episodes and ...

Last Updated: 23 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Factor V Deficiency" returned 2 free, full-text review articles on human participants. First 3 results:

Factor V deficiency.
 

Author(s): Rosanna Asselta, Flora Peyvandi

Journal: Semin. Thromb. Hemost.. 2009 Jun;35(4):382-9.

 

Congenital factor V (FV) deficiency is a bleeding disorder associated with mild to severe hemorrhagic symptoms and a prevalence in the general population of 1 in 1,000,000 in the homozygous form. Patients with FV deficiency and clinically significant manifestations (mainly involving ...

Last Updated: 14 Jul 2009

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Factor V deficiency in a patient with rheumatoid arthritis.
 

Author(s): F Omata, Y Ichikawa, H Nozaki, H Nomoto, S Arimori

Journal: Jpn. J. Med.. ;30(2):157-60.

 

Factor V deficiency associated with rheumatoid arthritis was found in a 54-year-old woman. Hereditary factor V deficiency is very rare; only about 150 cases have been reported since its discovery in 1943. This appears to be the first case report of factor V deficiency associated with ...

Last Updated: 11 Sep 1991

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.