Ewing's Sarcoma

Common Name(s)

Ewing's Sarcoma, Ewing Sarcoma, Ewings Sarcoma

Ewing's sarcoma is a malignant (cancerous) bone tumor that affects children. It can occur any time during childhood and young adulthood, but usually develops during puberty, when bones are growing rapidly. The tumor may arise anywhere in the body, usually in the long bones of the arms and legs, the pelvis, or the chest. It may also develop in the skull or the flat bones of the trunk. There are few symptoms. The most common is pain and occasionally swelling at the site of the tumor. Fever may also be present. The tumor often spreads (metastasis) to the lungs and other bones. The cause of Ewing's sarcoma is unknown.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ewing's Sarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ewing's Sarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ewing's Sarcoma" returned 279 free, full-text research articles on human participants. First 3 results:

[A diffuse bony Ewing's sarcoma].
 

Author(s): Madiha Mahfoudhi, Anis Hariz, Khaoula Ben Abdelghani, Sami Turki, Adel Kheder

Journal: Tunis Med. 2014 Jun;92(6):421-2.

 

Last Updated: 6 Mar 2015

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Proliferation index: a continuous model to predict prognosis in patients with tumours of the Ewing's sarcoma family.
 

Author(s): Samantha Brownhill, Dena Cohen, Sue Burchill

Journal:

 

The prognostic value of proliferation index (PI) and apoptotic index (AI), caspase-8, -9 and -10 expression have been investigated in primary Ewing's sarcoma family of tumours (ESFT). Proliferating cells, detected by immunohistochemistry for Ki-67, were identified in 91% (91/100) ...

Last Updated: 27 Aug 2014

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Survival of patients with Ewing's sarcoma in Yazd-Iran.
 

Author(s): Ali Akhavan, Fariba Binesh, Hadi Shamshiri, Fazllolah Ghanadi

Journal: Asian Pac. J. Cancer Prev.. 2014 ;15(12):4861-4.

 

The Ewing's sarcoma family is a group of small round cell tumors which accounts for 10-15% of all primary bone neoplasms. The aim of this study was to evaluate the survival of Ewing's sarcoma patients in our province and to determine of influencing factors.

Last Updated: 7 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ewing's Sarcoma" returned 24 free, full-text review articles on human participants. First 3 results:

Primary Ewing's sarcoma of the cranium: case series and review of literature.
 

Author(s): Kalpathi Krishnamani, Thota Narender Kumar, Linga Vijay Gandhi, Digumarti Raghunadharao, Gundeti Sadashivudu, Uppin Megha

Journal: J Cancer Res Ther. ;10(2):377-80.

 

Primary Ewing's sarcoma (EWS) of the cranium is extremely rare. It accounts for <1% of cases. We retrospectively analyzed our EWS cases to determine those which had a primary cranial involvement. Out of a total of 332 cases of EWS registered between the years 2000 and 2011, 7 were ...

Last Updated: 15 Jul 2014

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Intradural extramedullary Ewing's sarcoma. Recurrence with acute clinical presentation and literature review.
 

Author(s): Alberto Bazzocchi, Antonella Bacci, Elena Serchi, Angela Salerno, Eugenio Salizzoni, Marco Leonardi

Journal: Neuroradiol J. 2013 Aug;26(4):476-81.

 

The intradural extramedullary space is an extremely unusual site for the onset of Ewing's sarcoma. We describe a case of recurrence of intradural extramedullary Ewing's sarcoma and review the literature available on this topic.

Last Updated: 6 Sep 2013

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Promiscuous partnerships in Ewing's sarcoma.
 

Author(s): Savita Sankar, Stephen L Lessnick

Journal: Cancer Genet. 2011 Jul;204(7):351-65.

 

Ewing's sarcoma is a highly aggressive bone and soft tissue tumor of children and young adults. At the molecular genetic level Ewing's sarcoma is characterized by a balanced reciprocal translocation, t(11;22)(q24;q12), which encodes an oncogenic fusion protein and transcription factor ...

Last Updated: 29 Aug 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
 

Status: Recruiting

Condition Summary: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET); Childhood Supratentorial Primitive Neuroectodermal Tumor; Ewing Sarcoma of Bone; Extraosseous Ewing Sarcoma; Extraosseous Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Peripheral Primitive Neuroectodermal Tumor of the Kidney; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

 

Last Updated: 17 Mar 2015

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Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors
 

Status: Recruiting

Condition Summary: Desmoplastic Small Round Cell Tumor; Ewing Sarcoma of Bone or Soft Tissue; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

 

Last Updated: 4 Feb 2015

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Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
 

Status: Recruiting

Condition Summary: Askin Tumor; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

 

Last Updated: 12 May 2015

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