Esthesioneuroblastoma

Common Name(s)

Esthesioneuroblastoma

Esthesioneuroblastoma is a rare cancer of the upper part of the nasal cavity called the cribiform plate, which is a bone deep in the skull between the eyes, and above the ethmoid sinuses. It develops in nerve tissue associated with the sense of smell and can occur in people of any age. This cancer is very uncommon, accounting for 7 percent of all cancers of the nasal cavity and paranasal sinuses. Although it generally grows slowly, an esthesioneuroblastoma can sometimes grow very quickly. Fast-growing tumors can metastasize (spread) even many years after treatment of the initial tumor.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esthesioneuroblastoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esthesioneuroblastoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Esthesioneuroblastoma" returned 37 free, full-text research articles on human participants. First 3 results:

Prognostic utility of Hyams histological grading and Kadish-Morita staging systems for esthesioneuroblastoma outcomes.
 

Author(s): Diana Bell, Rami Saade, Dianna Roberts, Thomas J Ow, Michael Kupferman, Franco DeMonte, Ehab Y Hanna

Journal: Head Neck Pathol. 2015 Mar;9(1):51-9.

 

Esthesioneuroblastoma (ENB) is derived from the specialized olfactory neuroepithelium. Hyams grading and Kadish staging have been used to prognosticate and to guide treatment decisions. In this study, we sought to validate the prognostic utility of these systems in a large ENB cohort. ...

Last Updated: 2 Apr 2015

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[Ethmoid esthesioneuroblastoma presenting with ophthalmologic manifestations].
 

Author(s): D T Nguyen, H Eluecque, A Russel, B Toussaint, C Vigouroux, B Marie, R Jankowski

Journal: J Fr Ophtalmol. 2014 Jun;37(6):e87-9.

 

Last Updated: 10 Jun 2014

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Hyperostotic esthesioneuroblastoma: rare variant and fibrous dysplasia mimicker.
 

Author(s): Manzoor Ahmed, Phillip Daniel Knott

Journal: Korean J Radiol. ;15(1):156-60.

 

A 65-year-old male presented with a 3-year history of orbital symptoms. An imaging-based diagnosis of fibrous dysplasia involving the skull base was made at another institution. CT showed a diffuse sinonasal mass and ground-glass appearance of the bones of the anterior skull base ...

Last Updated: 5 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Esthesioneuroblastoma" returned 11 free, full-text review articles on human participants. First 3 results:

Sphenoidal esthesioneuroblastoma treated with sequential chemo radiotherapy: a case report and review of the literature.
 

Author(s): Omar Abdel-Rahman, Khaled Kamal

Journal: J Cancer Res Ther. ;10(4):1101-3.

 

Esthesioneuroblastoma (ENB)-also known as olfactory neuroblastoma-originates primarily from the olfactory epithelium in the roof of the nasal cavity. We present here the 7th reported case of ENB arising from the sphenoidal sinus. We undertook a review of the case notes from the time ...

Last Updated: 12 Jan 2015

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Atypical esthesioneuroblastoma invading oral cavity: a case report and review of the literature.
 

Author(s): Sandra Ventorin von Zeidler, Rafaela Guidi, Rita de Cássia Gonçalves Alencar, Renato Aguiar, Elismauro Francisco Mendonça, Aline Carvalho Batista, Rejane Faria Ribeiro-Rotta

Journal:

 

Esthesioneuroblastoma is an uncommon tumour of neuroectodermal origin. The authors describe a rare presentation of an atypical esthesioneuroblastoma invading oral cavity. The clinical presentation, aetiology, diagnosis, and management of this condition are discussed. The patient developed ...

Last Updated: 6 Mar 2014

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Endoscopic treatment of esthesioneuroblastoma.
 

Author(s): Eduardo Machado Rossi Monteiro, Marcelo Guerra Lopes, Emerson Rodrigo Santos, Caroline Valverde Diniz, Aurélia Silva E Albuquerque, Ana Paula de Aquino Ferreira Monteiro, Mauro Becker Martins Vieira

Journal: Braz J Otorhinolaryngol. ;77(2):171-7.

 

Esthesioneuroblastoma is an uncommon malignant tumor of the nasal vault. Treatment consists of craniofacial resection. As endoscopic techniques have advanced, this approach has been recommended to avoid morbidity and to reduce costs.

Last Updated: 3 May 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Esthesioneuroblastoma: Outcomes After Treatment
 

Status: Recruiting

Condition Summary: Esthesioneuroblastoma, Olfactory

 

Last Updated: 19 Oct 2015

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Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinoma; Squamous Cell Carcinoma; Sinonasal Carcinoma; Sinonasal Undifferentiated Carcinoma; Mucoepidermoid Carcinoma; Schneiderian Carcinoma; Myoepithelial Carcinoma; Esthesioneuroblastoma; Melanoma

 

Last Updated: 10 Feb 2016

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18F FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy
 

Status: Recruiting

Condition Summary: Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Male Breast Cancer; Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma; Recurrent Adenoid Cystic Carcinoma of the Oral Cavity; Recurrent Adult Brain Tumor; Recurrent Basal Cell Carcinoma of the Lip; Recurrent Breast Cancer; Recurrent Colon Cancer; Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity; Recurrent Hypopharyngeal Cancer; Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity; Recurrent Laryngeal Cancer; Recurrent Lip and Oral Cavity Cancer; Recurrent Lymphoepithelioma of the Nasopharynx; Recurrent Lymphoepithelioma of the Oropharynx; Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity; Recurrent Mucoepidermoid Carcinoma of the Oral Cavity; Recurrent Nasopharyngeal Cancer; Recurrent Non-small Cell Lung Cancer; Recurrent Oropharyngeal Cancer; Recurrent Pancreatic Cancer; Recurrent Paranasal Sinus and Nasal Cavity Cancer; Recurrent Rectal Cancer; Recurrent Renal Cell Cancer; Recurrent Salivary Gland Cancer; Stage IIIA Breast Cancer; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Breast Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer; Stage IV Non-small Cell Lung Cancer; Stage IV Pancreatic Cancer; Stage IV Renal Cell Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVA Salivary Gland Cancer; Stage IVB Colon Cancer; Stage IVB Salivary Gland Cancer; Stage IVC Salivary Gland Cancer; Tongue Cancer; Unspecified Adult Solid Tumor, Protocol Specific

 

Last Updated: 16 Nov 2015

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