Esophageal Cancer

Common Name(s)

Esophageal Cancer

Esophageal cancer is a cancer of the esophagus, the hollow tube that carries food and liquids from the throat to the stomach. As the cancer grows, symptoms may include painful or difficult swallowing, weight loss and coughing up blood. The exact cause is usually not known, but both environmental and genetic factors are throught to play a role in the development of this condition. In the United States, risk factors for developing esophageal cancer include smoking, heavy drinking, obesity, and damage from acid reflux. Treatments include surgery, radiation, chemotherapy, and laser therapy. Some patients may also need nutritional support, since the cancer or treatment may make it hard to swallow.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

Last Updated: 19 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

http://www.ECAware.org

Last Updated: 19 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Esophageal Cancer" returned 1736 free, full-text research articles on human participants. First 3 results:

Assessment of graft perfusion and oxygenation for improved outcome in esophageal cancer surgery: Protocol for a single-center prospective observational study.
 

Author(s): Elke Van Daele, Yves Van Nieuwenhove, Wim Ceelen, Christiaan Vanhove, Bart P Braeckman, Anne Hoorens, Jurgen Van Limmen, Oswald Varin, Dirk Van de Putte, Wouter Willaert, Piet Pattyn

Journal: Medicine (Baltimore). 2018 Sep;97(38):e12073.

 

The main cause of anastomotic leakage (AL) is tissue hypoxia, which results from impaired perfusion of the pedicle stomach graft after esophageal reconstruction. Clinical judgment is unreliable in determining graft perfusion. Therefore, an objective, validated, and reproducible method ...

Last Updated: 31 Dec 1969

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Investigation of melanoma-associated antigen A4 cancer/testis antigen clinical relevance in esophageal squamous cell carcinoma.
 

Author(s): Soodabeh Abbasi Sani, Mohammad Mahdi Forghanifard, Noorieh Sharifi, Mahnaz Hashemi Bidokhti, Alireza Jian Bagherpoor, Mohammad Reza Abbaszadegan

Journal: J Cancer Res Ther. ;14(5):1059-1064.

 

Esophageal squamous cell carcinoma (ESCC) is considered as the seventh most common cancer worldwide, and the second prevalent malignancy in the north of Iran. A subfamily group of tumor-specific antigens, commonly specified as cancer/testis antigens (CTAs), are expressed restrictedly ...

Last Updated: 31 Dec 1969

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Immunoregulatory influence of abundant MFG-E8 expression by esophageal cancer treated with chemotherapy.
 

Author(s): Takashi Kanemura, Hiroshi Miyata, Tomoki Makino, Koji Tanaka, Keijiro Sugimura, Mika Hamada-Uematsu, Yu Mizote, Hiroaki Uchida, Yasuhiro Miyazaki, Tsuyoshi Takahashi, Yukinori Kurokawa, Makoto Yamasaki, Hisashi Wada, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki, Hideaki Tahara

Journal: Cancer Sci.. 2018 Nov;109(11):3393-3402.

 

Milk fat globule-epidermal growth factor factor 8 (MFG-E8) is secreted from macrophages and is known to induce immunological tolerance mediated by regulatory T cells. However, the roles of the MFG-E8 that is expressed by cancer cells have not yet been fully examined. Expression of ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Esophageal Cancer" returned 172 free, full-text review articles on human participants. First 3 results:

The prognostic impact of tumor length in esophageal cancer: Protocol for a systematic review and meta-analysis.
 

Author(s): Xiangwei Zhang, Yang Wang, Yuanzhu Jiang, Zhaoyang Wang, Linping Zhao, Xianbiao Xue, Shaowei Sang, Lin Zhang

Journal: Medicine (Baltimore). 2018 Oct;97(43):e12902.

 

More and more studies were performed to explore the prognostic role of tumor length in esophageal cancer (EC). However, the results remain controversial. Hence, the aim of the review was to evaluate the association between tumor length and oncologic outcome in EC patients through meta-analysis.

Last Updated: 31 Dec 1969

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Induction therapy for clinical stage T2N0M0 esophageal cancer: A systematic review and meta-analysis.
 

Author(s): Hong-Wei Lv, Wen-Qun Xing, Si-Ning Shen, Ji-Wei Cheng

Journal: Medicine (Baltimore). 2018 Oct;97(40):e12651.

 

It is still controversial whether patients with clinical T2N0M0 (cT2N0M0) esophageal cancer are treated with induction therapy. The aim of this study was to determine the effect of induction therapy on cT2N0M0 esophageal cancer.

Last Updated: 31 Dec 1969

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Prognostic significance of programmed death ligand-1 immunohistochemical expression in esophageal cancer: A meta-analysis of the literature.
 

Author(s): Weiwei Yu, Yanmei Guo

Journal: Medicine (Baltimore). 2018 Jul;97(30):e11614.

 

It is thought that expression of programmed death ligand-1 (PD-L1) in esophageal cancer (EC) might compromise patient survival. However, the association between PD-L1 expression and survival of patients with EC remains controversial.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 23 Jan 2018

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Esophageal Cancer Tissue Banking
 

Status: Recruiting

Condition Summary: Esophageal Cancer

 

Last Updated: 4 May 2018

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Last Updated: 13 Jun 2018

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