Esophageal Cancer

Common Name(s)

Esophageal Cancer

Esophageal cancer is a cancer of the esophagus, the hollow tube that carries food and liquids from the throat to the stomach. As the cancer grows, symptoms may include painful or difficult swallowing, weight loss and coughing up blood. The exact cause is usually not known, but both environmental and genetic factors are throught to play a role in the development of this condition. In the United States, risk factors for developing esophageal cancer include smoking, heavy drinking, obesity, and damage from acid reflux. Treatments include surgery, radiation, chemotherapy, and laser therapy. Some patients may also need nutritional support, since the cancer or treatment may make it hard to swallow.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

Last Updated: 19 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

http://www.ECAware.org

Last Updated: 19 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Esophageal Cancer" returned 1306 free, full-text research articles on human participants. First 3 results:

Citrus Fruit Intake Substantially Reduces the Risk of Esophageal Cancer: A Meta-Analysis of Epidemiologic Studies.
 

Author(s): Anqiang Wang, Chengpei Zhu, Lilan Fu, Xueshuai Wan, Xiaobo Yang, Haohai Zhang, Ruoyu Miao, Lian He, Xinting Sang, Haitao Zhao

Journal: Medicine (Baltimore). 2015 Sep;94(39):e1390.

 

Many epidemiologic studies indicate a potential association between fruit and vegetable intake and various cancers. The purpose of this meta-analysis is to investigate the association between citrus fruit intake and esophageal cancer risk. The authors conducted a comprehensive search ...

Last Updated: 2 Oct 2015

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The correlation between high body mass index and survival in patients with esophageal cancer after curative esophagectomy: evidence from retrospective studies.
 

Author(s): Wenbiao Pan, Zhiyong Sun, Yangwei Xiang, Wentao Fang

Journal: Asia Pac J Clin Nutr. 2015 ;24(3):480-8.

 

To investigate the predictive value of high body mass index (H-BMI) on the survival of patients with esophageal cancer (EC) after curative esophagectomy.

Last Updated: 30 Sep 2015

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The Impact of Postoperative Complications on Survivals After Esophagectomy for Esophageal Cancer.
 

Author(s): Eisuke Booka, Hiroya Takeuchi, Tomohiko Nishi, Satoru Matsuda, Takuji Kaburagi, Kazumasa Fukuda, Rieko Nakamura, Tsunehiro Takahashi, Norihito Wada, Hirofumi Kawakubo, Tai Omori, Yuko Kitagawa

Journal: Medicine (Baltimore). 2015 Aug;94(33):e1369.

 

The aim of this study was to assess the impact of postoperative complications after esophagectomy on long-term outcome.The treatment of esophageal cancer has recently been improved; however, esophagectomy with thoracotomy and laparotomy carries considerable postoperative morbidity ...

Last Updated: 20 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Esophageal Cancer" returned 112 free, full-text review articles on human participants. First 3 results:

Meta-Analysis of Prognostic and Clinical Significance of CD44v6 in Esophageal Cancer.
 

Author(s): Bangli Hu, Wei Luo, Rui-Ting Hu, You Zhou, Shan-Yu Qin, Hai-Xing Jiang

Journal: Medicine (Baltimore). 2015 Aug;94(31):e1238.

 

CD44v6 is a cell adhesion molecule that plays an important role in the development and progression of esophageal cancer. However, the prognostic value and clinical significance of CD44v6 in esophageal cancer remains controversial. In the present study, we aimed to clarify these relationships ...

Last Updated: 8 Aug 2015

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Androgens and esophageal cancer: What do we know?
 

Author(s): Olga A Sukocheva, Bin Li, Steven L Due, Damian J Hussey, David I Watson

Journal: World J. Gastroenterol.. 2015 May;21(20):6146-56.

 

Significant disparities exist between genders for the development and progression of several gastro-intestinal (GI) diseases including cancer. Differences in incidence between men vs women for colon, gastric and hepatocellular cancers suggest a role for steroid sex hormones in regulation ...

Last Updated: 2 Jun 2015

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Minimally invasive esophagectomy for esophageal cancer: techniques and outcomes.
 

Author(s): K Petropoulos, A Macheras, T Liakakos, E P Misiakos,

Journal: Chirurgia (Bucur). ;110(2):99-108.

 

Despite recent improvements in diagnosis, surgical treatment and neo-adjuvant therapy, patients with esophageal cancer have poor prognosis with overall 5-year survival rates of 5-15%.Esophagectomy is the standard treatment for resectable esophageal cancer, but only one third of patients ...

Last Updated: 27 May 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Apatinib for Metastatic Esophageal Cancer.
 

Status: Recruiting

Condition Summary: Esophageal Cancer; Metastatic Esophageal Cancer; Apatinib

 

Last Updated: 10 Oct 2015

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SBRT Combined With Thymalfasin for Metastatic Esophageal Cancer
 

Status: Not yet recruiting

Condition Summary: Esophageal Cancer; Metastatic Esophageal Cancer; Stereotactic Body Radiation Therapy; Thymalfasin

 

Last Updated: 10 Oct 2015

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Pembrolizumab With Locally Delivered Radiation Therapy for the Initial Treatment of Metastatic Esophageal Cancers
 

Status: Not yet recruiting

Condition Summary: Esophageal Neoplasms; Esophageal Cancer; Cancer of the Esophagus

 

Last Updated: 24 Dec 2015

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