Esophageal Cancer

Common Name(s)

Esophageal Cancer

Esophageal cancer is a cancer of the esophagus, the hollow tube that carries food and liquids from the throat to the stomach. As the cancer grows, symptoms may include painful or difficult swallowing, weight loss and coughing up blood. The exact cause is usually not known, but both environmental and genetic factors are throught to play a role in the development of this condition. In the United States, risk factors for developing esophageal cancer include smoking, heavy drinking, obesity, and damage from acid reflux. Treatments include surgery, radiation, chemotherapy, and laser therapy. Some patients may also need nutritional support, since the cancer or treatment may make it hard to swallow.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

Last Updated: 19 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

http://www.ECAware.org

Last Updated: 19 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Esophageal Cancer" returned 1492 free, full-text research articles on human participants. First 3 results:

Endoscopic Tumor Length Should Be Reincluded in the Esophageal Cancer Staging System: Analyses of 662 Consecutive Patients.
 

Author(s): Michele Valmasoni, Elisa Sefora Pierobon, Alberto Ruol, Carlo Alberto De Pasqual, Gianpietro Zanchettin, Lucia Moletta, Renato Salvador, Mario Costantini, Stefano Merigliano

Journal:

 

Esophageal cancer represents the 6th cause of cancer mortality in the World. New treatments led to outcome improvements, but patient selection and prognostic stratification is a critical aspect to gain maximum benefit from therapies. Today, patients are stratified into 9 prognostic ...

Last Updated: 19 Apr 2016

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Prognostic Significance of 2-Deoxy-2-[18F]-Fluoro-D-Glucose PET/CT in Patients With Locally Advanced Esophageal Cancer Undergoing Neoadjuvant Chemoradiotherapy Before Surgery: A Nonparametric Approach.
 

Author(s): Assuero Giorgetti, Giovanni Pallabazzer, Andrea Ripoli, Biagio Solito, Dario Genovesi, Monica Lencioni, Maria Grazia Fabrini, Simone D'Imporzano, Laura Pieraccini, Paolo Marzullo, Stefano Santi

Journal: Medicine (Baltimore). 2016 Mar;95(13):e3151.

 

To investigate the prognostic value of tumor metabolism measurements on serial 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography and computed tomography scans in patients with locally advanced esophageal cancer undergoing neoadjuvant chemoradiotherapy. Forty-five patients ...

Last Updated: 5 Apr 2016

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The Serum Concentrations of Chemokine CXCL12 and Its Specific Receptor CXCR4 in Patients with Esophageal Cancer.
 

Author(s): Marta Łukaszewicz-Zając, Barbara Mroczko, Mirosław Kozłowski, Maciej Szmitkowski

Journal: Dis. Markers. 2016 ;2016():7963895.

 

Recent investigations have suggested that upregulated levels of inflammatory biomarkers, such as chemokines, may be associated with development of many malignancies, including esophageal cancer (EC). Based on our knowledge, this study is the first to assess the serum concentration ...

Last Updated: 4 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Esophageal Cancer" returned 123 free, full-text review articles on human participants. First 3 results:

The role of cancer-associated fibroblasts in esophageal cancer.
 

Author(s): Jiangfeng Wang, Guangyu Zhang, Jianbo Wang, Lu Wang, Xiaochen Huang, Yufeng Cheng

Journal:

 

Fibroblasts are known as critical stromal cells in wound healing by synthesizing extracellular matrix and collagen. A subpopulation of them is called cancer-associated fibroblasts (CAFs), because their production of proteins participated in various biological activities including ...

Last Updated: 29 Jan 2016

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Bisphosphonates and evidence for association with esophageal and gastric cancer: a systematic review and meta-analysis.
 

Author(s): Ellen Wright, Peter T Schofield, Mariam Molokhia

Journal:

 

Concerns have been raised about a possible link between bisphosphonate use, and in particular alendronate, and upper gastrointestinal (UGI) cancer. A number of epidemiological studies have been published with conflicting results. We conducted a systematic review and meta-analysis ...

Last Updated: 8 Dec 2015

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Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma.
 

Author(s): Hidetaka Sugihara, Takatsugu Ishimoto, Keisuke Miyake, Daisuke Izumi, Yoshifumi Baba, Naoya Yoshida, Masayuki Watanabe, Hideo Baba

Journal:

 

Esophageal cancer is one of the most common cancers worldwide. Esophageal squamous cell carcinoma (ESCC) is the major histological type of esophageal cancer in Eastern Asian countries. Several types of noncoding RNAs (ncRNAs) function as key epigenetic regulators of gene expression ...

Last Updated: 27 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 21 Jun 2016

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Low-dose Aspirin Therapy for Esophageal Cancer
 

Status: Not yet recruiting

Condition Summary: Esophageal Cancer

 

Last Updated: 2 Jan 2016

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Genetic and Environmental Risk Factors Related to Esophageal Cancer
 

Status: Recruiting

Condition Summary: Esophageal Cancer

 

Last Updated: 30 Sep 2015

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