Esophageal Cancer

Common Name(s)

Esophageal Cancer

Esophageal cancer is a cancer of the esophagus, the hollow tube that carries food and liquids from the throat to the stomach. As the cancer grows, symptoms may include painful or difficult swallowing, weight loss and coughing up blood. The exact cause is usually not known, but both environmental and genetic factors are throught to play a role in the development of this condition. In the United States, risk factors for developing esophageal cancer include smoking, heavy drinking, obesity, and damage from acid reflux. Treatments include surgery, radiation, chemotherapy, and laser therapy. Some patients may also need nutritional support, since the cancer or treatment may make it hard to swallow.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

Last Updated: 19 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

http://www.ECAware.org

Last Updated: 19 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Esophageal Cancer" returned 1027 free, full-text research articles on human participants. First 3 results:

Hypertrophic osteoarthropathy associated with esophageal cancer.
 

Author(s): Takamasa Murosaki, Katsusuke Mori, Takao Nagashima, Seiji Minota

Journal: Intern. Med.. 2015 ;54(3):357-8.

 

Last Updated: 9 Mar 2015

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XPD Lys751Gln polymorphisms and the risk of esophageal cancer: an updated meta-analysis.
 

Author(s): Xu-Feng Guo, Jun Wang, Xiao-Fei Lei, Yan-Ping Zeng, Wei-Guo Dong

Journal: Intern. Med.. 2015 ;54(3):251-9.

 

Published data regarding the association between xeroderma pigmentosum group D XPD Lys751Gln polymorphisms and esophageal cancer (EC) cancer remain controversial. The present meta-analysis aimed to obtain a more precise estimation of the relationship between XPD Lys751Gln polymorphisms ...

Last Updated: 9 Mar 2015

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Serum adiponectin relates to shortened overall survival in men with squamous cell esophageal cancer treated with preoperative concurrent chemoradiotherapy: a pilot study.
 

Author(s): Milada Zemanová, Barbora Staňková, Zuzana Ušiakova, Eva Tvrzická, Alexandr Pazdro, Luboš Petruželka, Miroslav Zeman

Journal:

 

The convergence of nutritional, genetic, and inflammatory factors plays a significant role in the pathophysiology of squamous cell esophageal cancer (SCEC). The parameters of inflammation, indices of nutritional status, and adipocyte-derived hormones such as leptin, adiponectin, and ...

Last Updated: 21 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Esophageal Cancer" returned 98 free, full-text review articles on human participants. First 3 results:

Physical activity is associated with reduced risk of esophageal cancer, particularly esophageal adenocarcinoma: a systematic review and meta-analysis.
 

Author(s): Siddharth Singh, Swapna Devanna, Jithinraj Edakkanambeth Varayil, Mohammad Hassan Murad, Prasad G Iyer

Journal:

 

Physical activity has been inversely associated with risk of several cancers. We performed a systematic review and meta-analysis to evaluate the association between physical activity and risk of esophageal cancer (esophageal adenocarcinoma [EAC] and/or esophageal squamous cell carcinoma [ESCC]).

Last Updated: 16 Jun 2014

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Endoscopic submucosal dissection vs endoscopic mucosal resection for superficial esophageal cancer.
 

Author(s): Hui-Min Guo, Xiao-Qi Zhang, Min Chen, Shu-Ling Huang, Xiao-Ping Zou

Journal: World J. Gastroenterol.. 2014 May;20(18):5540-7.

 

To investigate the effectiveness of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) in treating superficial esophageal cancer (SEC).

Last Updated: 16 May 2014

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Association between esophageal cancer risk and EPHX1 polymorphisms: a meta-analysis.
 

Author(s): Qin-Tao Li, Wei Kang, Man Wang, Jun Yang, Yang Zuo, Wei Zhang, Dan-Ke Su

Journal: World J. Gastroenterol.. 2014 May;20(17):5124-30.

 

To summarize the relationship between p.Tyr113His and p.His139Arg polymorphisms in microsomal epoxide hydrolase (EPHX1) and risk for esophageal cancer (EC).

Last Updated: 7 May 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetic and Environmental Risk Factors Related to Esophageal Cancer
 

Status: Recruiting

Condition Summary: Esophageal Cancer

 

Last Updated: 17 Dec 2009

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Esophageal Cancer Genetics Studies
 

Status: Recruiting

Condition Summary: Esophageal Cancer; Gastric (Cardia, Body) Cancer

 

Last Updated: 7 Apr 2015

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PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy
 

Status: Recruiting

Condition Summary: Adenocarcinoma of the Gastroesophageal Junction; Esophageal Cancer

 

Last Updated: 15 Feb 2013

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