Esophageal Cancer

Common Name(s)

Esophageal Cancer

Esophageal cancer is a cancer of the esophagus, the hollow tube that carries food and liquids from the throat to the stomach. As the cancer grows, symptoms may include painful or difficult swallowing, weight loss and coughing up blood. The exact cause is usually not known, but both environmental and genetic factors are throught to play a role in the development of this condition. In the United States, risk factors for developing esophageal cancer include smoking, heavy drinking, obesity, and damage from acid reflux. Treatments include surgery, radiation, chemotherapy, and laser therapy. Some patients may also need nutritional support, since the cancer or treatment may make it hard to swallow.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

Last Updated: 19 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Esophageal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Esophageal Cancer Awareness Association, Inc.

The Esophageal Cancer Awareness Association (ECAA) is dedicated to providing outreach for esophageal cancer patients, caregivers and survivors, to foster public awareness of this disease, to stimulate and promote esophageal cancer research efforts, and to offer education and information in a supportive environment.

http://www.ECAware.org

Last Updated: 19 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Esophageal Cancer" returned 1394 free, full-text research articles on human participants. First 3 results:

ICAM1 Is a Potential Cancer Stem Cell Marker of Esophageal Squamous Cell Carcinoma.
 

Author(s): Sheng-Ta Tsai, Po-Jen Wang, Nia-Jhen Liou, Pei-Shan Lin, Chung-Hsuan Chen, Wei-Chao Chang

Journal:

 

Esophageal squamous cell carcinoma (ESCC) accounts for about 90% of esophageal cancer diagnosed in Asian countries, with its incidence on the rise. Cancer stem cell (CSC; also known as tumor-initiating cells, TIC) is inherently resistant to cytotoxic chemotherapy and radiation and ...

Last Updated: 17 Nov 2015

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Endoscopic Submucosal Dissection (ESD) with Additional Therapy for Superficial Esophageal Cancer with Submucosal Invasion.
 

Author(s): Atsuki Ikeda, Namiko Hoshi, Tetsuya Yoshizaki, Yoshimi Fujishima, Tsukasa Ishida, Yoshinori Morita, Yasuo Ejima, Takashi Toyonaga, Yoshihiro Kakechi, Hiroshi Yokosaki, Takeshi Azuma

Journal: Intern. Med.. 2015 ;54(22):2803-13.

 

The standard treatment for submucosal esophageal cancer is esophagectomy or chemoradiotherapy (CRT). However, these treatment modalities could deteriorate the general condition and quality of life of the patients who are intolerant to invasive therapy. It is therefore important and ...

Last Updated: 16 Nov 2015

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18F-FDG PET-CT after Neoadjuvant Chemoradiotherapy in Esophageal Cancer Patients to Optimize Surgical Decision Making.
 

Author(s): Maarten C J Anderegg, Elisabeth J de Groof, Suzanne S Gisbertz, Roel J Bennink, Sjoerd M Lagarde, Jean H G Klinkenbijl, Marcel G W Dijkgraaf, Jacques J G H M Bergman, Maarten C C M Hulshof, Hanneke W M van Laarhoven, Mark I van Berge Henegouwen

Journal:

 

Prognosis of esophageal cancer patients can be significantly improved by neoadjuvant chemoradiotherapy (nCRT). Given the aggressive nature of esophageal tumors, it is conceivable that in a significant portion of patients treated with nCRT, dissemination already becomes manifest during ...

Last Updated: 4 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Esophageal Cancer" returned 118 free, full-text review articles on human participants. First 3 results:

Meta-Analysis of Prognostic and Clinical Significance of CD44v6 in Esophageal Cancer.
 

Author(s): Bangli Hu, Wei Luo, Rui-Ting Hu, You Zhou, Shan-Yu Qin, Hai-Xing Jiang

Journal: Medicine (Baltimore). 2015 Aug;94(31):e1238.

 

CD44v6 is a cell adhesion molecule that plays an important role in the development and progression of esophageal cancer. However, the prognostic value and clinical significance of CD44v6 in esophageal cancer remains controversial. In the present study, we aimed to clarify these relationships ...

Last Updated: 8 Aug 2015

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Systematic review and network meta-analysis: neoadjuvant chemoradiotherapy for locoregional esophageal cancer.
 

Author(s): Ta-Chen Huang, Chih-Hung Hsu, Chia-Chi Lin, Yu-Kang Tu

Journal: Jpn. J. Clin. Oncol.. 2015 Nov;45(11):1023-8.

 

Neoadjuvant chemoradiotherapy improves survival in patients with locoregional esophageal cancer. This study compares the efficacy of two common regimens, paclitaxel plus platinum and platinum plus 5-fluorouracil, based on overall survival.

Last Updated: 28 Oct 2015

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Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries.
 

Author(s): María José Domper Arnal, Ángel Ferrández Arenas, Ángel Lanas Arbeloa

Journal: World J. Gastroenterol.. 2015 Jul;21(26):7933-43.

 

Esophageal cancer is one of the most unknown and deadliest cancers worldwide, mainly because of its extremely aggressive nature and poor survival rate. Esophageal cancer is the 6(th) leading cause of death from cancer and the 8(th) most common cancer in the world. The 5-year survival ...

Last Updated: 18 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Apatinib for Metastatic Esophageal Cancer.
 

Status: Recruiting

Condition Summary: Esophageal Cancer; Metastatic Esophageal Cancer; Apatinib

 

Last Updated: 10 Oct 2015

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SBRT Combined With Thymalfasin for Metastatic Esophageal Cancer
 

Status: Recruiting

Condition Summary: Esophageal Cancer; Metastatic Esophageal Cancer; Stereotactic Body Radiation Therapy; Thymalfasin

 

Last Updated: 17 Apr 2016

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Pembrolizumab With Locally Delivered Radiation Therapy for the Initial Treatment of Metastatic Esophageal Cancers
 

Status: Recruiting

Condition Summary: Esophageal Neoplasms; Esophageal Cancer; Cancer of the Esophagus

 

Last Updated: 8 Jun 2016

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