Epithelioid Sarcoma

Common Name(s)

Epithelioid Sarcoma

Epithelioid sarcoma is a rare cancer that most often occurs in the soft tissue of the fingers, hands and forearms of young adults.   It may also be found in the legs, trunk, head or neck regions.  It is rare in young children and adults, and it occurs more frequently in men.   Epithelioid sarcoma begins as a painless, firm growth or bump that may be accompanied by an open wound (ulceration) in the skin covering the growth.   It is considered an aggressive cancer because it has a high chance of regrowing after treatment (a recurrence), or spreading to surrounding tissues or more distant parts of the body (a metastasis).   Epithelioid sarcoma is first treated with surgery to remove all the cancer cells (wide local excision).   Amputation of part of the affected limb may be needed in severe cases.   Radiation therapy or chemotherapy may also be used to destroy any cancer cells not removed during surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Epithelioid Sarcoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Epithelioid Sarcoma" returned 61 free, full-text research articles on human participants. First 3 results:

Epithelioid inflammatory myofibroblastic sarcoma responsive to surgery and an ALK inhibitor in a patient with panhypopituitarism.
 

Author(s): Kotomi Kurihara-Hosokawa, Isao Kawasaki, Anna Tamai, Yoko Yoshida, Yosuke Yakushiji, Hiroki Ueno, Mariko Fukumoto, Hiroko Fukushima, Takeshi Inoue, Masayuki Hosoi

Journal: Intern. Med.. 2014 ;53(19):2211-4.

 

We encountered a case of epithelioid inflammatory myofibroblastic sarcoma (EIMS) originating from an abdominal organ that rapidly regrew twice. The patient underwent two surgeries. Large tumors grew within three months after the second surgery. The patient subsequently received chemotherapy ...

Last Updated: 2 Oct 2014

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ALK inhibition for the treatment of refractory epithelioid inflammatory myofibroblastic sarcoma.
 

Author(s): Mikihiro Fujiya, Yutaka Kohgo

Journal: Intern. Med.. 2014 ;53(19):2177-8.

 

Last Updated: 2 Oct 2014

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A genetic dichotomy between pure sclerosing epithelioid fibrosarcoma (SEF) and hybrid SEF/low-grade fibromyxoid sarcoma: a pathologic and molecular study of 18 cases.
 

Author(s): Carlos Prieto-Granada, Lei Zhang, Hsiao-Wei Chen, Yun-Shao Sung, Narasimhan P Agaram, Achim A Jungbluth, Cristina R Antonescu

Journal: Genes Chromosomes Cancer. 2015 Jan;54(1):28-38.

 

Sclerosing epithelioid fibrosarcoma (SEF) is a rare soft tissue tumor exhibiting considerable morphologic overlap with low-grade fibromyxoid sarcoma (LGFMS). Moreover, both SEF and LGFMS show MUC4 expression by immunohistochemistry. While the majority of LGFMS cases are characterized ...

Last Updated: 14 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Epithelioid Sarcoma" returned 5 free, full-text review articles on human participants. First 3 results:

Vulvar "proximal-type" epithelioid sarcoma: report of a case and review of the literature.
 

Author(s): Lodovico Patrizi, Giacomo Corrado, Maria Saltari, Letizia Perracchio, Chiara Scelzo, Emilio Piccione, Enrico Vizza

Journal:

 

The "proximal-type" epithelioid sarcoma is a very rare kind of mesenchimal tumor characterized by the difficulty in histological diagnosis and the very aggressive biological behavior.

Last Updated: 20 Aug 2013

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Epithelioid sarcoma in a child presenting as a submandibular mass.
 

Author(s): S Al-Salam, M Al Ashari

Journal: Afr Health Sci. 2010 Dec;10(4):400-4.

 

Last Updated: 18 Mar 2011

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Epithelioid sarcoma: a diagnostic challenge.
 

Author(s): Kanthilatha K Pai, Sathish B Pai, H Sripathi, , Purnima Rao

Journal: Indian J Dermatol Venereol Leprol. ;72(6):446-8.

 

Epithelioid sarcoma is an uncommon slow-growing soft tissue malignancy, associated with a high incidence of local recurrence and metastasis. We report a 26-year-old male with epithelioid sarcoma on the right palm with a long history of over seven years, which was initially misdiagnosed ...

Last Updated: 20 Dec 2006

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Adult Fibrosarcoma; Alveolar Soft Part Sarcoma; Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Clear Cell Sarcoma of Soft Tissue; Epithelioid Malignant Peripheral Nerve Sheath Tumor; Epithelioid Sarcoma; Extraskeletal Myxoid Chondrosarcoma; Extraskeletal Osteosarcoma; Fibrohistiocytic Neoplasm; Glomus Tumor of the Skin; Inflammatory Myofibroblastic Tumor; Intimal Sarcoma; Leiomyosarcoma; Liposarcoma; Low Grade Fibromyxoid Sarcoma; Low Grade Myofibroblastic Sarcoma; Malignant Cutaneous Granular Cell Tumor; Malignant Peripheral Nerve Sheath Tumor; Malignant Triton Tumor; Mesenchymal Chondrosarcoma; Myxofibrosarcoma; Myxoid Chondrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Nerve Sheath Neoplasm; PEComa; Pericytic Neoplasm; Plexiform Fibrohistiocytic Tumor; Sclerosing Epithelioid Fibrosarcoma; Stage IB Soft Tissue Sarcoma; Stage IIB Soft Tissue Sarcoma; Stage III Soft Tissue Sarcoma; Stage IV Soft Tissue Sarcoma; Synovial Sarcoma; Undifferentiated (Embryonal) Sarcoma; Undifferentiated High Grade Pleomorphic Sarcoma of Bone

 

Last Updated: 26 Jun 2015

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Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma
 

Status: Recruiting

Condition Summary: Adult Alveolar Soft Part Sarcoma; Adult Angiosarcoma; Adult Desmoplastic Small Round Cell Tumor; Adult Epithelioid Hemangioendothelioma; Adult Epithelioid Sarcoma; Adult Extraskeletal Myxoid Chondrosarcoma; Adult Extraskeletal Osteosarcoma; Adult Fibrosarcoma; Adult Leiomyosarcoma; Adult Liposarcoma; Adult Malignant Mesenchymoma; Adult Malignant Peripheral Nerve Sheath Tumor; Adult Rhabdomyosarcoma; Adult Synovial Sarcoma; Adult Undifferentiated Pleomorphic Sarcoma; Malignant Adult Hemangiopericytoma; Recurrent Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma

 

Last Updated: 24 Jun 2015

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Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
 

Status: Recruiting

Condition Summary: Childhood Alveolar Soft-part Sarcoma; Childhood Angiosarcoma; Childhood Desmoplastic Small Round Cell Tumor; Childhood Epithelioid Sarcoma; Childhood Fibrosarcoma; Childhood Leiomyosarcoma; Childhood Liposarcoma; Childhood Malignant Mesenchymoma; Childhood Neurofibrosarcoma; Childhood Synovial Sarcoma; Chordoma; Desmoid Tumor; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Recurrent Childhood Soft Tissue Sarcoma

 

Last Updated: 6 May 2015

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