Epilepsy

Common Name(s)

Epilepsy

Epilepsy is a chronic neurological (brain) condition that is characterized by recurrent unprovoked seizures. In a typical brain, small electrical charges or signals are sent from the nerves in the brain to other areas of the body. A seizure occurs when the normal electrical activity in the brain is interrupted by intense bursts of energy. For someone to be diagnosed with epilepsy, he or she must experience at least two seizures unrelated to any kind of infection or trauma. Epilepsy is caused by improper pathways of these electrical signals in the brain, a chemical imbalance of nerve signaling, or both. These differences or abnormalities may have resulted from previous head injuries, lead poisoning, genetics, or previous infections. However, many times the cause is unknown.

Although the symptoms of a seizure can affect any part of the body, the electrical event that caused the seizure is always in the brain. When an individual experiences a seizure, they may experience strange sensations, emotions, behaviors, convulsions, muscle spasms, and loss of consciousness. The frequency of seizures is variable among persons with the condition. Epilepsy not only affects one's health, but also impacts their relationships, driving abilities, safety, and work. The goal of treatment is to stop or manage seizures and to improve quality of life. This can often be done through proper medications. The majority of individuals with proper treatment can become seizure free within a few years, others may experience occasional seizures and still others may continue with uncontrolled seizures. It is best to talk to your doctor to find the right treatment plan for you. Support groups are also a good source of information and way to connect with other individuals and families affected by epilepsy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Epilepsy" for support, advocacy or research.

Citizens United for Research in Epilepsy

Citizens United for Research in Epilepsy (CURE) is a nonprofit organization dedicated to finding a cure for epilepsy by raising funds for research and by increasing awareness of the prevalence and devastation of this disease.

Last Updated: 6 May 2014

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CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

Last Updated: 12 Oct 2013

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Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

Last Updated: 9 Mar 2015

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Epilepsy Support Network of Orange County

The Epilepsy Support Network of Orange County is committed to building a community of support to improve the lives of those affected by epilepsy through education, programs and advocacy.

Last Updated: 19 Feb 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 16 Mar 2015

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Idic15 Canada

Idic15 Canada is a national non-profit with a Global reach, responsible for expediting quality, coordination, accessibility and research of medical care and social support innovations for families living with the rare disorder Chromosome 15q11.2-13.1 Duplication Syndrome. We will uphold our mission by: Providing information and emotional support to individuals with Chromosome 15q11.2-13.1 Duplication Syndrome, their families, and the professionals who work with them. Developing resources and increasing global awareness and understanding of this syndrome to help build medical collaborations globally. Encouraging, supporting, and raising funds for global research into a wide range of issues related to this Syndrome. Idic15 Canada has facilitated the development of 4 national syndrome specific clinics and coordinated medical teams throughout the country. We also have the development of a Chromosome 15q11.2-13.1 Duplication Syndrome patient registry designed to spark in

Last Updated: 1 Oct 2014

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International Foundation for CDKL5 Research

To lead the way in finding a cure and treatments for CDKL5 disorder by funding global research efforts and increasing awareness while enhancing the quality of life for those affected by CDKL5 disorder, by providing information, programs, and services.

Last Updated: 19 Feb 2013

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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KCNQ2 Cure Alliance

The mission of KCNQ2 Cure Alliance is to educate and to advance research leading to treatments or a cure for patients living with the genetic disorder KCNQ2 Epilepsy.

Last Updated: 9 Apr 2015

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Missouri Family to Family

Missouri Family to Family provides customized information that allows families and individuals about needed resources and supports, navigating the maze of systems and services, as well as options to make their vision for their life possible. MOF2F also offers Sharing Our Strengths, which connects individuals with disabilities and/or their caregivers to a person who is available to listen with an open heart and open mind, offering emotional support, practical information, and/or shared experiences.

Last Updated: 15 Apr 2014

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

Last Updated: 11 Apr 2013

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General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Epilepsy" for support, advocacy or research.

Citizens United for Research in Epilepsy

Citizens United for Research in Epilepsy (CURE) is a nonprofit organization dedicated to finding a cure for epilepsy by raising funds for research and by increasing awareness of the prevalence and devastation of this disease.

http://www.CUREepilepsy.org

Last Updated: 6 May 2014

View Details
Logo
CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

http://www.cnsfoundation.org

Last Updated: 12 Oct 2013

View Details
Logo
Epilepsy Foundation - Home Office

The mission of the Epilepsy Foundation is to stop seizures and SUDEP, find a cure and overcome the challenges created by epilepsy through efforts including education, advocacy and research to accelerate ideas into therapies.

http://www.epilepsyfoundation.org

Last Updated: 9 Mar 2015

View Details
Epilepsy Support Network of Orange County

The Epilepsy Support Network of Orange County is committed to building a community of support to improve the lives of those affected by epilepsy through education, programs and advocacy.

http://www.EpilepsySupportNet.org

Last Updated: 19 Feb 2013

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 16 Mar 2015

View Details
Idic15 Canada

Idic15 Canada is a national non-profit with a Global reach, responsible for expediting quality, coordination, accessibility and research of medical care and social support innovations for families living with the rare disorder Chromosome 15q11.2-13.1 Duplication Syndrome. We will uphold our mission by: Providing information and emotional support to individuals with Chromosome 15q11.2-13.1 Duplication Syndrome, their families, and the professionals who work with them. Developing resources and increasing global awareness and understanding of this syndrome to help build medical collaborations globally. Encouraging, supporting, and raising funds for global research into a wide range of issues related to this Syndrome. Idic15 Canada has facilitated the development of 4 national syndrome specific clinics and coordinated medical teams throughout the country. We also have the development of a Chromosome 15q11.2-13.1 Duplication Syndrome patient registry designed to spark in

http://www.idic15canada.ca

Last Updated: 1 Oct 2014

View Details
Logo
International Foundation for CDKL5 Research

To lead the way in finding a cure and treatments for CDKL5 disorder by funding global research efforts and increasing awareness while enhancing the quality of life for those affected by CDKL5 disorder, by providing information, programs, and services.

http://www.CDKL5.com

Last Updated: 19 Feb 2013

View Details
Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

View Details
KCNQ2 Cure Alliance

The mission of KCNQ2 Cure Alliance is to educate and to advance research leading to treatments or a cure for patients living with the genetic disorder KCNQ2 Epilepsy.

http://www.kcnq2cure.org/

Last Updated: 9 Apr 2015

View Details
Logo
Missouri Family to Family

Missouri Family to Family provides customized information that allows families and individuals about needed resources and supports, navigating the maze of systems and services, as well as options to make their vision for their life possible. MOF2F also offers Sharing Our Strengths, which connects individuals with disabilities and/or their caregivers to a person who is available to listen with an open heart and open mind, offering emotional support, practical information, and/or shared experiences.

http://www.mofamilytofamily.org

Last Updated: 15 Apr 2014

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

View Details
The Arc of East Central Iowa

The Arc of East Central Iowa empowers people with intellectual and related disabilities to engage in lifelong opportunities to live, learn, work and play with dignity, freedom and full inclusion in their communities.

http://www.arceci.org

Last Updated: 11 Apr 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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General Resources

Family Resources

Supports, ideas, tools and more are available for families to review in the Family Resources category. Learn about financial benefits in your province, to a printable caregiver sheet.

Uploaded By: Idic15 Canada

Updated 1 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Epilepsy" returned 3858 free, full-text research articles on human participants. First 3 results:

Angiocentric glioma: a treatable cause of epilepsy: report of a rare case.
 

Author(s): Aanchal Kakkar, Mehar Chand Sharma, Vaishali Suri, Seema Kaushal, Sarat P Chandra, Ajay Garg, Chitra Sarkar

Journal: Neurol India. ;62(6):677-9.

 

Last Updated: 16 Jan 2015

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Co-morbidity of depression and epilepsy in Jimma University specialized hospital, Southwest Ethiopia.
 

Author(s): Hagos Tsegabrhan, Alemayehu Negash, Kenfe Tesfay, Mubarek Abera

Journal: Neurol India. ;62(6):649-55.

 

Depression is a serious and frequent co-morbid illness among people with epilepsy (PWE) and the risk for depression in PWE is higher than the general population. However, depression among PWE is often under diagnosed and treated by physicians other than psychiatrists in resource-limited ...

Last Updated: 16 Jan 2015

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Clinical and neuropsychological assessment of executive function in a sample of children and adolescents with idiopathic epilepsy.
 

Author(s): Andrea Bandeira de Lima, Fernanda Moreira, Marleide da Mota Gomes, Heber Maia-Filho

Journal: Arq Neuropsiquiatr. 2014 Dec;72(12):954-9.

 

To compare the executive functions of children and adolescents with idiopathic epilepsy with a control group and to correlate with clinical data, intelligence and academic performance.

Last Updated: 18 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Epilepsy" returned 660 free, full-text review articles on human participants. First 3 results:

Epilepsy: some controversies, some knowledge and some experience from Cambodia.
 

Author(s): Chamroeun Hun, Tola Hok, Sina Ros, Samleng Chan, Devender Bhalla

Journal: Neurol India. ;62(6):606-9.

 

Epilepsy-related health outcomes remain unacceptably low in much of the developing world. According to us, it is because of the failure since long to see, and address, epilepsy beyond its preset conventional image. The objective of this paper was to highlight the presence, and influence, ...

Last Updated: 16 Jan 2015

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Epidemiology of neurological disorders in India: review of background, prevalence and incidence of epilepsy, stroke, Parkinson's disease and tremors.
 

Author(s): M Gourie-Devi

Journal: Neurol India. ;62(6):588-98.

 

Growth and development of neuroepidemiology in India during the last four decades has been documented highlighting the historical milestones. The prevalence rates of the spectrum of neurological disorders from different regions of the country ranged from 967-4,070 with a mean of 2394 ...

Last Updated: 16 Jan 2015

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When should MERRF (myoclonus epilepsy associated with ragged-red fibers) be the diagnosis?
 

Author(s): Paulo José Lorenzoni, Rosana Herminia Scola, Cláudia Suemi Kamoi Kay, Carlos Eduardo S Silvado, Lineu Cesar Werneck

Journal: Arq Neuropsiquiatr. 2014 Oct;72(10):803-11.

 

Myoclonic epilepsy associated with ragged red fibers (MERRF) is a rare mitochondrial disorder. Diagnostic criteria for MERRF include typical manifestations of the disease: myoclonus, generalized epilepsy, cerebellar ataxia and ragged red fibers (RRF) on muscle biopsy. Clinical features ...

Last Updated: 23 Oct 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetics of Severe Early Onset Epilepsies
 

Status: Recruiting

Condition Summary: Epilepsy; Epileptic Encephalopathy; Ohtahara Syndrome; Infantile Spasms; Dravet Syndrome; Malignant Migrating Partial Epilepsy of Infancy; Early Myoclonic Epileptic Encephalopathy

 

Last Updated: 2 Feb 2015

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Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study
 

Status: Recruiting

Condition Summary: Childhood Absence Epilepsy; Epilepsy; Seizures

 

Last Updated: 9 Aug 2012

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Surgery as a Treatment for Medically Intractable Epilepsy
 

Status: Recruiting

Condition Summary: Epilepsy; Epilepsy, Temporal Lobe; Partial Epilepsy

 

Last Updated: 19 Jul 2014

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