Epidermolysis Bullosa Acquisita

Common Name(s)

Epidermolysis Bullosa Acquisita

Epidermolysis bullosa acquisita (EBA) is a rare autoimmune disorder that causes the skin to blister in response to minor injury. Common areas of blistering include the hands, feet, knees, elbows, and buttocks. It can also affect the mouth, nose, and eyes. Some affected people have other health problems such as Crohn's disease, systemic lupus erythematosus, amyloidosis, or multiple myeloma. EBA is not inherited and usually occurs in adulthood. Treatment aims to protect the skin, stop the formation of blisters, and promote healing. Immunosuppressive drugs may be used to reduce the body's autoimmune response.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Epidermolysis Bullosa Acquisita" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Epidermolysis Bullosa Acquisita" returned 60 free, full-text research articles on human participants. First 3 results:

Epidermolysis bullosa acquisita associated with dysphagia and stricture of esophagus.
 

Author(s): Sunil Vyankatrao Pawar, Ashok Rohidas Mohite, Ravindra Ganpat Surude, Pravin Motilal Rathi, Chitra Shivanand Nayak

Journal: Indian J Dermatol Venereol Leprol. ;82(6):717-719.

 

Last Updated: 19 Sep 2016

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Epidermolysis Bullosa Acquisita Develops in Dominant Dystrophic Epidermolysis Bullosa.
 

Author(s): Ryota Hayashi, Ken Natsuga, Mika Watanabe, Hiroaki Iwata, Satoru Shinkuma, Akiko Ito, Yukiko Masui, Masaaki Ito, Yutaka Shimomura

Journal: J. Invest. Dermatol.. 2016 Jan;136(1):320-3.

 

Last Updated: 14 Jan 2016

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Paraneoplastic Epidermolysis Bullosa Acquisita Associated with Thyroid Carcinoma.
 

Author(s): Giuseppe Alfonso Lombardo, Maria Antonietta Pilla, Roberto Benucci, Alessandro Monopoli, Gianandrea Baliva, Tommaso Gobello, Giovanni Di Zenzo, Giovanna Zambruno, Liliana Guerra

Journal: Acta Derm. Venereol.. 2016 Mar;96(3):414-5.

 

Last Updated: 1 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Epidermolysis Bullosa Acquisita" returned 4 free, full-text review articles on human participants. First 3 results:

Cytoskeletal Regulation of Inflammation and Its Impact on Skin Blistering Disease Epidermolysis Bullosa Acquisita.
 

Author(s): Zlatko Kopecki, Ralf J Ludwig, Allison J Cowin

Journal:

 

Actin remodelling proteins regulate cytoskeletal cell responses and are important in both innate and adaptive immunity. These responses play a major role in providing a fine balance in a cascade of biological events that results in either protective acute inflammation or chronic inflammation ...

Last Updated: 16 Jul 2016

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Epidermolysis Bullosa Acquisita: From Pathophysiology to Novel Therapeutic Options.
 

Author(s): Michael Kasperkiewicz, Christian D Sadik, Katja Bieber, Saleh M Ibrahim, Rudolf A Manz, Enno Schmidt, Detlef Zillikens, Ralf J Ludwig

Journal: J. Invest. Dermatol.. 2016 Jan;136(1):24-33.

 

Epidermolysis bullosa acquisita (EBA) is a prototypic organ-specific autoimmune disease induced by autoantibodies to type VII collagen causing mucocutaneous blisters. In the inflammatory (bullous pemphigoid-like) EBA variant, autoantibody binding is followed by a lesional inflammatory ...

Last Updated: 14 Jan 2016

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Epidermolysis bullosa acquisita.
 

Author(s): Rishu Gupta, David T Woodley, Mei Chen

Journal: Clin. Dermatol.. ;30(1):60-9.

 

Epidermolysis bullosa acquisita (EBA) is a rare, acquired, chronic subepidermal bullous disease of the skin and mucosa characterized by autoantibodies to type VII collagen (C7) structures, a major component of anchoring fibrils, which attach the epidermis to the dermis. EBA patients ...

Last Updated: 5 Dec 2011

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
 

Status: Recruiting

Condition Summary: Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue; Pyoderma Gangrenosum; Erosive Pustular Dermatosis of the Scalp; Sweet's Syndrome; Behcet's Disease; Bowel-associated Dermatosis-arthritis Syndrome; Pustular Psoriasis; Acute Generalized Exanthematous Pustulosis; Keratoderma Blenorrhagicum; Sneddon-Wilkinson Disease; IgA Pemphigus; Amicrobial Pustulosis of the Folds; Infantile Acropustulosis; Transient Neonatal Pustulosis; Neutrophilic Eccrine Hidradenitis; Rheumatoid Neutrophilic Dermatitis; Neutrophilic Urticaria; Still's Disease; Erythema Marginatum; Unclassified Periodic Fever Syndromes / Autoinflammatory Syndromes; Dermatitis Herpetiformis; Linear IgA Bullous Dermatosis; Bullous Systemic Lupus Erythematosus; Inflammatory Epidermolysis Bullosa Aquisita; Neutrophilic Dermatosis of the Dorsal Hands (Pustular Vasculitis); Small Vessel Vasculitis Including Urticarial Vasculitis; Erythema Elevatum Diutinum; Medium Vessel Vasculitis

 

Last Updated: 26 Sep 2016

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