Enteropathy-associated T-cell lymphoma

Common Name(s)

Enteropathy-associated T-cell lymphoma

Enteropathy-associated T-cell lymphoma (EATL) is a very rare form of intestinal cancer that affects T-cells. T-cells are a type of white blood cell that function as part of the body’s adaptive immune system. This type of cancer is most commonly seen in individuals with chronic or untreated celiac disease. Celiac disease is an autoimmune disorder of the small intestine in which the body is unable to process gluten.

Symptoms of EATL include diarrhea, nausea, fatigue, abdominal pain, and rapid weight loss. This type of cancer is more common in those of European descent. If celiac disease is diagnosed with EATL, then the initial treatment will usually involve adaptation of a gluten-free diet. Additional treatment for the cancer will vary widely between individuals, but may involve a combination of chemotherapy, radiation, and other mediations. Talk to your doctor about the most current treatment options and to find available support groups.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Enteropathy-associated T-cell lymphoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Enteropathy-associated T-cell lymphoma" returned 47 free, full-text research articles on human participants. First 3 results:

[Acute intestinal obstruction revealing enteropathy associated t-cell lymphoma, about a case].
 

Author(s): Abdoul Aziz Garba, Harissou Adamou, Ibrahim Amadou Magagi, Souleymane Brah, Oumarou Habou

Journal:

 

Enteropathy associated T-cell lymphoma (EATL) is a rare complication of celiac disease (CD). We report a case of EATL associated with CD revealed by acute intestinal obstruction. A North African woman of 38 years old with a history of infertility and chronic abdominal pain was admitted ...

Last Updated: 24 May 2016

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Endoscopic Findings of Enteropathy-Associated T-Cell Lymphoma Type II: A Case Series.
 

Author(s): Yun Soo Hong, Young Sik Woo, Gaeun Park, Kyungho Lee, Soo Hoon Kang, Hyun Woo Lee, Eun Ran Kim, Sung Noh Hong, Dong Kyung Chang, Young Ho Kim, Poong-Lyul Rhee, Jae J Kim

Journal: Gut Liver. 2016 Jan;10(1):147-51.

 

Enteropathy-associated T-cell lymphoma (EATL) is a rare extranodal T-cell lymphoma arising from the intestine. Two types of EATL have been reported. In contrast to the classic EATL type I, EATL type II occurs sporadically, is unrelated to celiac disease, and comprises 10% to 20% of ...

Last Updated: 23 Dec 2015

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Genomic and immunohistochemical profiles of enteropathy-associated T-cell lymphoma in Japan.
 

Author(s): Sakura Tomita, Yara Y Kikuti, Joaquim Carreras, Minoru Kojima, Kiyoshi Ando, Hirotaka Takasaki, Rika Sakai, Katsuyoshi Takata, Tadashi Yoshino, Silvia Bea, Elias Campo, Naoya Nakamura

Journal: Mod. Pathol.. 2015 Oct;28(10):1286-96.

 

Enteropathy-associated T-cell lymphoma (EATL) is a rare primary T-cell lymphoma of the digestive tract. EATL is classified as either Type I, which is frequently associated with and thought to arise from celiac disease and is primarily observed in Northern Europe, and Type II, which ...

Last Updated: 30 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Enteropathy-associated T-cell lymphoma" returned 2 free, full-text review articles on human participants. First 3 results:

[Molecular pathogenesis of peripheral T cell lymphoma (2): extranodal NK/T cell lymphoma, nasal type, adult T cell leukemia/lymphoma and enteropathy associated T cell lymphoma].
 

Author(s): Lucile Couronné, Christian Bastard, Philippe Gaulard, Olivier Hermine, Olivier Bernard

Journal: Med Sci (Paris). 2015 Nov;31(11):1023-33.

 

Peripheral T-cell lymphomas (PTCL) belong to the group of non-Hodgkin lymphoma and particularly that of mature T /NK cells lymphoproliferative neoplasms. The 2008 WHO classification describes different PTCL entities with varying prevalence. With the exception of histologic subtype ...

Last Updated: 20 Nov 2015

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Enteropathy-associated T-cell lymphoma: a review on clinical presentation, diagnosis, therapeutic strategies and perspectives.
 

Author(s): M-O Chandesris, G Malamut, V Verkarre, B Meresse, E Macintyre, R Delarue, M-T Rubio, F Suarez, B Deau-Fischer, N Cerf-Bensussan, N Brousse, C Cellier, O Hermine

Journal: Gastroenterol. Clin. Biol.. 2010 Nov;34(11):590-605.

 

Enteropathy-associated T-cell lymphoma (EATL) is a rare complication of celiac disease (<1% of lymphomas) and has a poor prognosis.

Last Updated: 24 Nov 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

T Cells Expressing a Fully-Human Anti-CD30 Chimeric Antigen Receptor for Treating CD30-Expressing Lymphomas
 

Status: Recruiting

Condition Summary: Lymphoma, Large-Cell, Anaplasitc; Hodgkin Disease; Lymphoma, Hodgkins; Enteropathy-Associated T-Cell Lymphoma; Lymphoma, Extranodal NK-T-Cell

 

Last Updated: 1 Mar 2017

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Combination Chemotherapy and Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma
 

Status: Recruiting

Condition Summary: Anaplastic Large Cell Lymphoma, ALK-Negative; Anaplastic Large Cell Lymphoma, ALK-Positive; Hepatosplenic T-Cell Lymphoma; Peripheral T-Cell Lymphoma, Not Otherwise Specified; Stage II Angioimmunoblastic T-cell Lymphoma; Stage II Enteropathy-Associated T-Cell Lymphoma; Stage III Angioimmunoblastic T-cell Lymphoma; Stage III Enteropathy-Associated T-Cell Lymphoma; Stage IV Angioimmunoblastic T-cell Lymphoma; Stage IV Enteropathy-Associated T-Cell Lymphoma

 

Last Updated: 30 Oct 2016

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Nivolumab in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma
 

Status: Not yet recruiting

Condition Summary: Blastic Plasmacytoid Dendritic Cell Neoplasm; Hepatosplenic T-Cell Lymphoma; HTLV-1 Infection; NK-Cell Lymphoma, Unclassifiable; Primary Systemic Anaplastic Large Cell Lymphoma, ALK-Negative; Recurrent Adult T-Cell Leukemia/Lymphoma; Recurrent Anaplastic Large Cell Lymphoma; Recurrent Angioimmunoblastic T-cell Lymphoma; Recurrent Enteropathy-Associated T-Cell Lymphoma; Recurrent Mycosis Fungoides; Refractory Adult T-Cell Leukemia/Lymphoma; Refractory Anaplastic Large Cell Lymphoma; Refractory Angioimmunoblastic T-cell Lymphoma; Refractory Enteropathy-Associated T-Cell Lymphoma; Refractory Mycosis Fungoides; Refractory Nasal Type Extranodal NK/T-Cell Lymphoma; Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified

 

Last Updated: 6 Mar 2017

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