Endocarditis

Common Name(s)

Endocarditis

Endocarditis is condition affecting the heart lining, heart valves, or blood vessels. Endocarditis can be caused by bacterial or fungal infection (infective endocarditis) or by blood clots that form on the heart valves or lining (non-infective endocarditis or non-bacterial thrombotic endocarditis (NBTE)). In cases of infective endocarditis, the infected area becomes inflamed and immune cells can be seen in the affected area. In cases of non-infective endocarditis, there is no inflammation of the heart lining or valves.

The young and the old are at increased risk of experiencing endocarditis. Those with cancer, diabetes, HIV/AIDS, or a weakened immune system are also at an increased risk. Those with certain blood clotting conditions are at increased risk for NBTE. Symptoms of infective endocarditis can include fever, chills, fatigue, and achiness. Symptoms of both infective and non-infective endocarditis can include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment for infective endocarditis includes antibiotics. Treatment for NBTE usually includes anticoagulants to decrease the likelihood of blood clots and to help break up any existing clots. If you or a loved one has been diagnosed with endocarditis, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Endocarditis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Endocarditis" returned 2625 free, full-text research articles on human participants. First 3 results:

[Acute pulmonic valve endocarditis].
 

Author(s): Amine Tarmiz, Imene Mgarrech, Mehdi Slim, Najeh Ben Hlima, Chokri Kortas, Sofiane Jerbi

Journal:

 

Right heart endocarditis mainly affects tricuspid valve, especially in drug users. Isolated pulmonary valve infection is rare. We here report the case of a 32-year old young woman whose diagnosis of community-acquired pulmonary valve endocarditis was confirmed. This study is even ...

Last Updated: 8 Mar 2017

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[Broad ischemic stroke revealing infective endocarditis in a young patient: about a case].
 

Author(s): Fanomezantsoa Noella Ravelosaona, Julien Razafimahefa, Rahamefy Odilon Randrianasolo, Solofonirina Rakotoarimanana, Djacoba Alain Tehindrazanarivelo

Journal:

 

Broad ischemic stroke is mainly due to a cardiac embolus or to an atheromatous plaque. In young subjects, one of the main causes of ischemic stroke (broad ischemic stroke in particolar) is embolic heart disease including infective endocarditis. Infective endocarditis is a contraindication ...

Last Updated: 3 Feb 2017

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Retrospective Examination of Q Fever Endocarditis: An Underdiagnosed Disease in the Mainland of China.
 

Author(s): Xiao Han, Jeffrey Hsu, Qi Miao, Bao-Tong Zhou, Hong-Wei Fan, Xiao-Lu Xiong, Bo-Hai Wen, Lian Wu, Xiao-Wei Yan, Quan Fang, Wei Chen

Journal: Chin. Med. J.. ;130(1):64-70.

 

Q fever endocarditis, a chronic illness caused by Coxiella burnetii, can be fatal if misdiagnosed or left untreated. Despite a relatively high positive rate of Q fever serology in healthy individuals in the mainland of China, very few cases of Q fever endocarditis have been reported. ...

Last Updated: 4 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Endocarditis" returned 261 free, full-text review articles on human participants. First 3 results:

Fatal endocarditis with methicilin-sensible Staphylococcus aureus and major complications: rhabdomyolysis, pericarditis, and intracerebral hematoma: A case report and review of the literature.
 

Author(s): Anca Meda Georgescu, Leonard Azamfirei, Krisztina Szalman, Edit Szekely

Journal: Medicine (Baltimore). 2016 Oct;95(41):e5125.

 

Over the last decades Staphylococcus aureus (SA) has become the dominant etiology of native valve infective endocarditis, with the community-acquired methicillin-sensible Staphylococcus aureus (CA-MSSA) strains being the prevailing type.

Last Updated: 14 Oct 2016

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Managing infective endocarditis in the elderly: new issues for an old disease.
 

Author(s): Emmanuel Forestier, Thibaut Fraisse, Claire Roubaud-Baudron, Christine Selton-Suty, Leonardo Pagani

Journal:

 

The incidence of infective endocarditis (IE) rises in industrialized countries. Older people are more affected by this severe disease, notably because of the increasing number of invasive procedures and intracardiac devices implanted in these patients. Peculiar clinical and echocardiographic ...

Last Updated: 13 Sep 2016

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Central Venous Access Device-Related Bacillus Cereus Endocarditis: A Case Report and Review of the Literature.
 

Author(s): William F Wright

Journal: Clin Med Res. 2016 Jun;14(2):109-15.

 

Bacillus cereus typically presents as a gastrointestinal infection, but rarely manifests as systemic disease. This report describes a case of B. cereus-related endocarditis that presented as a sickle cell crisis and bacteremia. Initial clinical suspicion was for laboratory contamination ...

Last Updated: 12 Jul 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 17 Jun 2015

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Last Updated: 19 Oct 2016

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Endocarditis Registry of the University Hospital of Cologne (ER-UHC)
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 24 Oct 2016

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