Endocarditis

Common Name(s)

Endocarditis

Endocarditis is condition affecting the heart lining, heart valves, or blood vessels. Endocarditis can be caused by bacterial or fungal infection (infective endocarditis) or by blood clots that form on the heart valves or lining (non-infective endocarditis or non-bacterial thrombotic endocarditis (NBTE)). In cases of infective endocarditis, the infected area becomes inflamed and immune cells can be seen in the affected area. In cases of non-infective endocarditis, there is no inflammation of the heart lining or valves.

The young and the old are at increased risk of experiencing endocarditis. Those with cancer, diabetes, HIV/AIDS, or a weakened immune system are also at an increased risk. Those with certain blood clotting conditions are at increased risk for NBTE. Symptoms of infective endocarditis can include fever, chills, fatigue, and achiness. Symptoms of both infective and non-infective endocarditis can include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment for infective endocarditis includes antibiotics. Treatment for NBTE usually includes anticoagulants to decrease the likelihood of blood clots and to help break up any existing clots. If you or a loved one has been diagnosed with endocarditis, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Endocarditis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Endocarditis" returned 2958 free, full-text research articles on human participants. First 3 results:

[Microbiological approach to a possible infective endocarditis case caused by Aggregatibacter actinomycetemcomitans].
 

Author(s): Şaban Gürcan, Selahattin Ünlü, Figen Kuloğlu, Aynur Karadenizli, Mert Ahmet Kuşkucu

Journal: Mikrobiyol Bul. 2016 Apr;50(2):315-21.

 

Aggregatibacter (Actinobacillus) actinomycetemcomitans, a small, gram-negative coccobacillus that grows slow and fastidious, is generally colonized in the oral cavity. It is a rarely seen bacterium because of the difficulty of isolation but it can be a causative agent for dental infections ...

Last Updated: 14 May 2016

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Infective Endocarditis and Cancer Risk: A Population-Based Cohort Study.
 

Author(s): Li-Min Sun, Jung-Nan Wu, Cheng-Li Lin, Jen-Der Day, Ji-An Liang, Li-Ren Liou, Chia-Hung Kao

Journal: Medicine (Baltimore). 2016 Mar;95(12):e3198.

 

This study investigated the possible relationship between endocarditis and overall and individual cancer risk among study participants in Taiwan.We used data from the National Health Insurance program of Taiwan to conduct a population-based, observational, and retrospective cohort ...

Last Updated: 26 Mar 2016

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[Endocarditis and arthritis caused by extended spectrum β-lactamase-producing non-Typhi Salmonella].
 

Author(s): Mara García, Natalia García, Pablo Striebeck, Daniela Cejas, Viviana Rodríguez

Journal: Rev Chilena Infectol. 2016 Feb;33(1):71-4.

 

We present the case of a patient with endocarditis and arthritis caused by extended spectrum β-lactamase producing non-Typhi Salmonella, with incomplete response (defined as persistence of Salmonella in joint fluid) to initial instituted treatment (trimethoprim-sulfamethoxazole) ...

Last Updated: 11 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Endocarditis" returned 300 free, full-text review articles on human participants. First 3 results:

Lomentospora prolificans endocarditis--case report and literature review.
 

Author(s): Melissa Kelly, Robert Stevens, Pamela Konecny

Journal:

 

Lomentospora prolificans (formally Scedosporium prolificans) is an environmental mould with a global distribution. Endocarditis caused by L. prolificans is a rare but serious emerging disease in immunocompromised patients. Prior to this case there have only been eight cases reported ...

Last Updated: 29 Jan 2016

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Scedosporium prolificans Endocarditis: Case Report and Literature Review.
 

Author(s): Yoshitaka Wakabayashi, Shu Okugawa, Keita Tatsuno, Mahoko Ikeda, Yoshiki Misawa, Saho Koyano, Eiichi Tsuji, Shintaro Yanagimoto, Shuji Hatakeyama, Kyoji Moriya, Hiroshi Yotsuyanagi

Journal: Intern. Med.. 2016 ;55(1):79-82.

 

Scedosporium prolificans, a hyaline filamentous fungus, is widely distributed in the environment and is currently an emerging human pathogen, especially among immunocompromised patients. However, S. prolificans endocarditis is rare. We herein report a case of S. prolificans endocarditis ...

Last Updated: 15 Jan 2016

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Non-infective endocarditis with systemic embolization and recurrent stroke in systemic sclerosis.
 

Author(s): Ellen De Langhe, Alexandra Seghers, Philippe Demaerel, Patrick Verschueren, Robin Lemmens

Journal: Rheumatology (Oxford). 2016 Mar;55(3):589-91.

 

Last Updated: 10 Feb 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Long-term Clinico-radiological Evolution of Patients With Brain Lesions During Infectious Endocarditis
 

Status: Recruiting

Condition Summary: Infectious Endocarditis

 

Last Updated: 9 May 2016

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Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
 

Status: Not yet recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 30 Apr 2014

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Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 17 Jun 2015

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