Endocarditis

Common Name(s)

Endocarditis

Endocarditis is condition affecting the heart lining, heart valves, or blood vessels. Endocarditis can be caused by bacterial or fungal infection (infective endocarditis) or by blood clots that form on the heart valves or lining (non-infective endocarditis or non-bacterial thrombotic endocarditis (NBTE)). In cases of infective endocarditis, the infected area becomes inflamed and immune cells can be seen in the affected area. In cases of non-infective endocarditis, there is no inflammation of the heart lining or valves.

The young and the old are at increased risk of experiencing endocarditis. Those with cancer, diabetes, HIV/AIDS, or a weakened immune system are also at an increased risk. Those with certain blood clotting conditions are at increased risk for NBTE. Symptoms of infective endocarditis can include fever, chills, fatigue, and achiness. Symptoms of both infective and non-infective endocarditis can include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment for infective endocarditis includes antibiotics. Treatment for NBTE usually includes anticoagulants to decrease the likelihood of blood clots and to help break up any existing clots. If you or a loved one has been diagnosed with endocarditis, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Endocarditis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Endocarditis" returned 2711 free, full-text research articles on human participants. First 3 results:

Infective endocarditis in patients with cancer: a consequence of invasive procedures or a harbinger of neoplasm?: A prospective, multicenter cohort.
 

Author(s): Ana Fernández-Cruz, Patricia Muñoz, Carmen Sandoval, Carmen Fariñas, Manuel Gutiérrez-Cuadra, Juan M Pericás Pulido, José M Miró, Miguel Á Goenaga-Sánchez, Arístides de Alarcón, Francisco Bonache-Bernal, MªÁngeles Rodríguez, Mariam Noureddine, Emilio Bouza Santiago,

Journal: Medicine (Baltimore). 2017 Sep;96(38):e7913.

 

The aim of the study was to draw a comparison between the characteristics of infective endocarditis (IE) in patients with cancer and those of IE in noncancer patients.Patients with IE, according to the modified Duke criteria, were prospectively included in the GAMES registry between ...

Last Updated: 20 Sep 2017

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Dental procedures, antibiotic prophylaxis, and endocarditis among people with prosthetic heart valves: nationwide population based cohort and a case crossover study.
 

Author(s): Sarah Tubiana, Pierre-Olivier Blotière, Bruno Hoen, Philippe Lesclous, Sarah Millot, Jérémie Rudant, Alain Weill, Joel Coste, François Alla, Xavier Duval

Journal:

 

Objective To assess the relation between invasive dental procedures and infective endocarditis associated with oral streptococci among people with prosthetic heart valves.Design Nationwide population based cohort and a case crossover study.Setting French national health insurance ...

Last Updated: 8 Sep 2017

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Contemporary In-Hospital and Long-Term Outcomes of Surgical Management for Fungal Endocarditis.
 

Author(s): Jinmiao Chen, Jun Li, Tianyu Zhou, Kui Hu, Zhaohua Yang, Yao Wang, Kai Zhu, Tao Hong, Hao Lai, Chunsheng Wang

Journal: Int Heart J. 2017 Aug;58(4):516-520.

 

Fungal endocarditis (FE) is a rare and fatal disease. The contemporary in-hospital and long-term surgical outcomes of FE have not been adequately evaluated. This study describes our experience with the surgical management of FE.Eight FE patients who underwent surgery in our center ...

Last Updated: 10 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Endocarditis" returned 271 free, full-text review articles on human participants. First 3 results:

The prognosis of infective endocarditis treated with biological valves versus mechanical valves: A meta-analysis.
 

Author(s): Ende Tao, Li Wan, WenJun Wang, YunLong Luo, JinFu Zeng, Xia Wu

Journal:

 

Surgery remains the primary form of treatment for infective endocarditis (IE). However, it is not clear what type of prosthetic valve provides a better prognosis. We conducted a meta-analysis to compare the prognosis of infective endocarditis treated with biological valves to cases ...

Last Updated: 13 Apr 2017

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Bacteremia caused by Bergeyella zoohelcum in an infective endocarditis patient: case report and review of literature.
 

Author(s): Yili Chen, Kang Liao, Lu Ai, Penghao Guo, Han Huang, Zhongwen Wu, Min Liu

Journal:

 

Bergeyella zoohelcum is an aerobic, Gram-negative bacterium that is frequently isolated from the upper respiratory tract of dogs, cats and other mammals. Clinically, B. zoohelcum has been reported causing cellulitis, tenosynovitis, leg abscess and septicemia, which is closely connected ...

Last Updated: 13 Apr 2017

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Could Early Surgery Get Beneficial in Adult Patients with Active Native Infective Endocarditis? A Meta-Analysis.
 

Author(s): Liqun Jia, Zanxin Wang, Qiang Fu, Huaien Bu, Minxin Wei

Journal: Biomed Res Int. 2017 ;2017():3459468.

 

After a thorough search through the database as PubMed database and Embase database, the clinical experimental articles have been selected out on the effects of early surgery on the treatment of active native infective endocarditis. The quality of the trials included in this study ...

Last Updated: 22 Mar 2017

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Partial Oral Treatment of Endocarditis
 

Status: Recruiting

Condition Summary: Endocarditis

 

Last Updated: 20 Jul 2017

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Last Updated: 19 Oct 2016

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Endocarditis Registry of the University Hospital of Cologne (ER-UHC)
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 1 May 2017

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