Endocarditis

Common Name(s)

Endocarditis

Endocarditis is condition affecting the heart lining, heart valves, or blood vessels. Endocarditis can be caused by bacterial or fungal infection (infective endocarditis) or by blood clots that form on the heart valves or lining (non-infective endocarditis or non-bacterial thrombotic endocarditis (NBTE)). In cases of infective endocarditis, the infected area becomes inflamed and immune cells can be seen in the affected area. In cases of non-infective endocarditis, there is no inflammation of the heart lining or valves.

The young and the old are at increased risk of experiencing endocarditis. Those with cancer, diabetes, HIV/AIDS, or a weakened immune system are also at an increased risk. Those with certain blood clotting conditions are at increased risk for NBTE. Symptoms of infective endocarditis can include fever, chills, fatigue, and achiness. Symptoms of both infective and non-infective endocarditis can include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment for infective endocarditis includes antibiotics. Treatment for NBTE usually includes anticoagulants to decrease the likelihood of blood clots and to help break up any existing clots. If you or a loved one has been diagnosed with endocarditis, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Endocarditis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Endocarditis" returned 2638 free, full-text research articles on human participants. First 3 results:

New insights into valve-related intramural and intracellular bacterial diversity in infective endocarditis.
 

Author(s): Andreas Oberbach, Nadine Schlichting, Stefan Feder, Stefanie Lehmann, Yvonne Kullnick, Tilo Buschmann, Conny Blumert, Friedemann Horn, Jochen Neuhaus, Ralph Neujahr, Erik Bagaev, Christian Hagl, Maximilian Pichlmaier, Arne Christian Rodloff, Sandra Gräber, Katharina Kirsch, Marcus Sandri, Vivek Kumbhari, Armirhossein Behzadi, Amirali Behzadi, Joao Carlos Correia, Friedrich Wilhelm Mohr, Maik Friedrich

Journal:

 

In infective endocarditis (IE), a severe inflammatory disease of the endocardium with an unchanged incidence and mortality rate over the past decades, only 1% of the cases have been described as polymicrobial infections based on microbiological approaches. The aim of this study was ...

Last Updated: 14 Apr 2017

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Gemella morbillorum endocarditis of pulmonary valve:a case report.
 

Author(s): Dan Li, Zhicheng Zhu, Xiaomei Zheng, Weitie Wang, Rihao Xu, Kexiang Liu

Journal:

 

Pulmonary valve infective endocarditis is a rare finding for endocarditis. Infective endocarditis caused by Gemella morbillorum remains a scanty occurrence.

Last Updated: 24 Mar 2017

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Mycobacterium goodii endocarditis following mitral valve ring annuloplasty.
 

Author(s): Rohan B Parikh, Matthew Grant

Journal:

 

Mycobacterium goodii is an infrequent human pathogen which has been implicated in prosthesis related infections and penetrating injuries. It is often initially misidentified as a gram-positive rod by clinical microbiologic laboratories and should be considered in the differential diagnosis.

Last Updated: 22 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Endocarditis" returned 263 free, full-text review articles on human participants. First 3 results:

Could Early Surgery Get Beneficial in Adult Patients with Active Native Infective Endocarditis? A Meta-Analysis.
 

Author(s): Liqun Jia, Zanxin Wang, Qiang Fu, Huaien Bu, Minxin Wei

Journal: Biomed Res Int. 2017 ;2017():3459468.

 

After a thorough search through the database as PubMed database and Embase database, the clinical experimental articles have been selected out on the effects of early surgery on the treatment of active native infective endocarditis. The quality of the trials included in this study ...

Last Updated: 22 Mar 2017

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Fatal endocarditis with methicilin-sensible Staphylococcus aureus and major complications: rhabdomyolysis, pericarditis, and intracerebral hematoma: A case report and review of the literature.
 

Author(s): Anca Meda Georgescu, Leonard Azamfirei, Krisztina Szalman, Edit Szekely

Journal: Medicine (Baltimore). 2016 Oct;95(41):e5125.

 

Over the last decades Staphylococcus aureus (SA) has become the dominant etiology of native valve infective endocarditis, with the community-acquired methicillin-sensible Staphylococcus aureus (CA-MSSA) strains being the prevailing type.

Last Updated: 14 Oct 2016

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Managing infective endocarditis in the elderly: new issues for an old disease.
 

Author(s): Emmanuel Forestier, Thibaut Fraisse, Claire Roubaud-Baudron, Christine Selton-Suty, Leonardo Pagani

Journal:

 

The incidence of infective endocarditis (IE) rises in industrialized countries. Older people are more affected by this severe disease, notably because of the increasing number of invasive procedures and intracardiac devices implanted in these patients. Peculiar clinical and echocardiographic ...

Last Updated: 13 Sep 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 17 Jun 2015

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Last Updated: 19 Oct 2016

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Endocarditis Registry of the University Hospital of Cologne (ER-UHC)
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 24 Oct 2016

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