Empty Sella Syndrome

Common Name(s)

Empty Sella Syndrome

Empty sella syndrome (ESS) is a condition that involves the sella turcica, a bony structure at the base of the brain that protects the pituitary gland. There is a primary and secondary form of the condition. The primary form occurs when a structural defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten. The secondary form occurs when the pituitary gland is damaged due to injury, a tumor, surgery or radiation therapy. Some people with ESS have no symptoms. People with secondary ESS may have symptoms of decreased pituitary function such as absence of menstruation, infertility, fatigue, and intolerance to stress and infection. In children, ESS may be associated with early onset of puberty, growth hormone deficiency, pituitary tumors, or pituitary gland dysfunction. Treatment focuses on the symptoms present in each person.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Empty Sella Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Empty Sella Syndrome" returned 25 free, full-text research articles on human participants. First 3 results:

Subclinical Cushing syndrome associated with an empty sella turcica.
 

Author(s): Masanori Yoshida, Misaki Miyata, Harumi Ueda, Yutaka Oiso

Journal: Intern. Med.. 2014 ;53(6):637-8.

 

Last Updated: 17 Mar 2014

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'Empty sella syndrome': a case of a patient with sodium succinate hydrocortisone allergy.
 

Author(s): Eleonora Nucera, Carla Lombardo, Arianna Aruanno, Amira Colagiovanni, Alessandro Buonomo, Tiziana de Pasquale, Valentina Pecora, Vito Sabato, Angela Rizzi, Lucilla Pascolini, Anna Giulia Ricci, Domenico Schiavino

Journal: Eur. J. Endocrinol.. 2011 Jan;164(1):139-40.

 

We present the case of a woman with 'empty sella syndrome' who experienced generalized urticaria after the administration of sodium succinate hydrocortisone in two episodes.

Last Updated: 14 Dec 2010

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Diagnostic dilemmas in a patient with anaemia. Empty sella syndrome--a case report.
 

Author(s): Michał Holecki, Edyta Rembiesa-Jarosińska, Agata Fryźlewicz-Moska, Jan Duława

Journal: Endokrynol Pol. ;61(4):400-3.

 

Empty sella syndrome is defined as a group of clinical symptoms developing as a result of herniation of the subarachnoid space within the sella, which is often associated with some degree of flattening of the pituitary gland. It is usually recognized incidentally during brain imaging ...

Last Updated: 31 Aug 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Empty Sella Syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

A case of hypothalamic panhypopituitarism with empty sella syndrome: case report and review of the literature.
 

Author(s): Hisako Komada, Masaaki Yamamoto, Saki Okubo, Kanto Nagai, Keiji Iida, Takehiro Nakamura, Yushi Hirota, Kazuhiko Sakaguchi, Masato Kasuga, Yutaka Takahashi

Journal: Endocr. J.. 2009 ;56(4):585-9.

 

Empty sella syndrome is frequently accompanied with pituitary dysfunction. Most of the patients with empty sella syndrome demonstrate primary pituitary or stalk dysfunction and few cases show hypothalamic dysfunction. A 71-year-old man manifested appetite loss, nausea and vomiting ...

Last Updated: 31 Jul 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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