Ehlers-Danlos Syndrome Vascular Type

Common Name(s)

Ehlers-Danlos Syndrome Vascular Type, Ehlers-Danlos syndrome, type 4

Ehlers-Danlos syndrome vascular type is a connective tissue disease. Symptoms include thin, translucent skin, easy bruising, characteristic facial appearance, and fragile arteries, intestine, and/or uterus. It is inherited in an autosomal dominant manner and is caused by mutations in the COL3A1 gene.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ehlers-Danlos Syndrome Vascular Type" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ehlers-Danlos Syndrome Vascular Type" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ehlers-Danlos Syndrome Vascular Type" returned 11 free, full-text research articles on human participants. First 3 results:

Vascular Ehlers-Danlos syndrome mutations in type III collagen differently stall the triple helical folding.
 

Author(s): Kazunori Mizuno, Sergei Boudko, Jürgen Engel, Hans Peter Bächinger

Journal: J. Biol. Chem.. 2013 Jun;288(26):19166-76.

 

Vascular Ehlers-Danlos syndrome (EDS) type IV is the most severe form of EDS. In many cases the disease is caused by a point mutation of Gly in type III collagen. A slower folding of the collagen helix is a potential cause for over-modifications. However, little is known about the ...

Last Updated: 1 Jul 2013

Go To URL
Femoral artery dissection in vascular type Ehlers-Danlos syndrome; leave well alone?
 

Author(s): M Singh, S Puppala, R C Pollitt, G J Sobey, D J A Scott

Journal: Eur J Vasc Endovasc Surg. 2012 Mar;43(3):341-2.

 

Vascular Ehlers-Danlos Syndrome (EDS) is a rare autosomal dominant condition resulting from a defect in type III procollagen synthesis. This causes the development of severe vascular pathologies, including arterial rupture and pseudoaneurysm formation. We present a case of a young ...

Last Updated: 6 Mar 2012

Go To URL
The vascular aneurysms of Ehlers-Danlos syndrome type IV.
 

Author(s): Jae-Youn Moon, Soo-Jin Lee, Tae Soo Kang

Journal: Eur. Heart J.. 2012 Feb;33(3):415.

 

Last Updated: 2 Feb 2012

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ehlers-Danlos Syndrome Vascular Type" returned 1 free, full-text review articles on human participants. First 3 results:

Vascular type of Ehlers-Danlos syndrome.
 

Author(s): Atsushi Watanabe, Takashi Shimada

Journal: J Nippon Med Sch. 2008 Oct;75(5):254-61.

 

Vascular type of Ehlers-Danlos syndrome (EDS), also known as EDS type IV (NIM#130050) is a life-threatening autosomal dominant inherited disorder of connective tissue, caused by mutations of the COL3A1 gene. Vascular EDS causes severe fragility of connective tissues with arterial ...

Last Updated: 21 Nov 2008

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Biomarkers in Vascular Ehlers-Danlos Syndrome
 

Status: Recruiting

Condition Summary: Vascular Ehlers-Danlos Syndrome

 

Last Updated: 13 Jun 2014

Go to URL
Wearing a Compression Garment for Patients With Hypermobility Type of Ehlers-Danlos Syndrome
 

Status: Recruiting

Condition Summary: Ehlers-Danlos Syndrome Hypermobility Type

 

Last Updated: 8 Jul 2014

Go to URL
Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes
 

Status: Not yet recruiting

Condition Summary: Marfan Syndrome; Loeys-Dietz Syndrome; Thoracic Aortic Aneurysm and Dissection Syndromes; Ehlers-Danlos Type IV Syndrome; Turner Syndrome

 

Last Updated: 8 Aug 2014

Go to URL