Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 20 May 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 20 May 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 560 free, full-text research articles on human participants. First 3 results:

Investigation of the actin scavenging system in pre-eclampsia.
 

Author(s): Dionne S Tannetta, Christopher W Redman, Ian L Sargent

Journal: Eur. J. Obstet. Gynecol. Reprod. Biol.. 2014 Jan;172():32-5.

 

Cell injury releases actin, the most abundant cell protein. Gelsolin and vitamin D binding protein (VDBP) together depolymerise and clear cell-free actin. Impaired actin clearance is associated with several diseases and correlates with clinical outcome. The actin scavenging system ...

Last Updated: 31 Dec 2013

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Maternal imbalance between pro-angiogenic and anti-angiogenic factors in HIV-infected women with pre-eclampsia.
 

Author(s): Nalini Govender, Thajasvarie Naicker, Jagidesa Moodley

Journal: Cardiovasc J Afr. 2013 Jun;24(5):174-9.

 

Angiogenic imbalance contributes to the development of preeclampsia. We evaluated the protein expression of the proangiogenic placental growth factor (PlGF) and transforming growth factor beta 1 (TGF-β1) compared with the anti-angiogenic soluble fms-like tyrosine kinase receptor ...

Last Updated: 12 Nov 2013

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Cardiovascular haemodynamics in pre-eclampsia using brain naturetic peptide and tissue Doppler studies.
 

Author(s): S Fayers, J Moodley, D P Naidoo

Journal: Cardiovasc J Afr. 2013 May;24(4):130-6.

 

To determine early haemodynamic changes in preeclampsia (PE) using tissue Doppler echocardiography and brain natriuretic peptide (BNP), and to relate these changes to obstetric outcomes.

Last Updated: 12 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 70 free, full-text review articles on human participants. First 3 results:

Biomarkers for the management of pre-eclampsia in pregnant women.
 

Author(s): Lakshmi Tanuja Petla, Rosy Chikkala, K S Ratnakar, Vijayalakshmi Kodati, V Sritharan

Journal: Indian J. Med. Res.. 2013 ;138():60-7.

 

Pre-eclampsia (PE) is a pregnancy related disorder characterized by hypertension and proteinuria noticeable after 20 wk of gestation. It is a leading cause of maternal and foetal mortality and morbidity worldwide. The aetiology of the disease is unknown, but recent studies have revealed ...

Last Updated: 23 Sep 2013

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Management of eclampsia and stroke during pregnancy.
 

Author(s): Yasumasa Ohno, Michiyasu Kawai, Shigehiko Morikawa, Katsumi Sakakibara, Kanji Tanaka, Kaoru Ishikawa, Fumitaka Kikkawa

Journal: Neurol. Med. Chir. (Tokyo). 2013 ;53(8):513-9.

 

To establish the etiologies and therapeutic strategies for the treatment of eclampsia and stroke during pregnancy, we performed a questionnaire-based study of stroke during pregnancy in Aichi prefecture (2005-2009). This study revealed the following findings: 66% of deliveries were ...

Last Updated: 27 Aug 2013

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Pathophysiology of hypertension in pre-eclampsia: a lesson in integrative physiology.
 

Author(s): A C Palei, F T Spradley, J P Warrington, E M George, J P Granger

Journal: Acta Physiol (Oxf). 2013 Jul;208(3):224-33.

 

Despite being one of the leading causes of maternal death and a major contributor of maternal and perinatal morbidity, the mechanisms responsible for the pathogenesis of pre-eclampsia have yet to be fully elucidated. However, it is evident that this is a complex disorder involving ...

Last Updated: 18 Jun 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 Feb 2009

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The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia; Eclampsia

 

Last Updated: 16 Mar 2014

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Community Level Interventions for Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia; Hypertension, Pregnancy Induced

 

Last Updated: 21 Mar 2014

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