Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 850 free, full-text research articles on human participants. First 3 results:

Economic evaluation of Community Level Interventions for Pre-eclampsia (CLIP) in South Asian and African countries: a study protocol.
 

Author(s): Asif R Khowaja, Craig Mitton, Stirling Bryan, Laura A Magee, Zulfiqar A Bhutta, Peter von Dadelszen

Journal:

 

Globally, hypertensive disorders of pregnancy, particularly pre-eclampsia and eclampsia, are the leading cause of maternal and neonatal mortality, and impose substantial burdens on the families of pregnant women, their communities, and healthcare systems. The Community Level Interventions ...

Last Updated: 28 May 2015

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Criteria-based audit of quality of care to women with severe pre-eclampsia and eclampsia in a referral hospital in Accra, Ghana.
 

Author(s): Joyce L Browne, Sabine W van Nievelt, Emmanuel K Srofenyoh, Diederick E Grobbee, Kerstin Klipstein-Grobusch

Journal:

 

Severe pre-eclampsia and eclampsia are one of the major causes of maternal mortality globally. Reducing maternal morbidity and mortality demands optimizing quality of care. Criteria-based audits are a tool to define, assess and improve quality of care. The aim of this study was to ...

Last Updated: 30 Apr 2015

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Molecular association of pathogenetic contributors to pre-eclampsia (pre-eclampsia associome).
 

Author(s): Andrey S Glotov, Evgeny S Tiys, Elena S Vashukova, Vladimir S Pakin, Pavel S Demenkov, Olga V Saik, Timofey V Ivanisenko, Olga N Arzhanova, Elena V Mozgovaya, Marina S Zainulina, Nikolay A Kolchanov, Vladislav S Baranov, Vladimir A Ivanisenko

Journal: BMC Syst Biol. 2015 ;9 Suppl 2():S4.

 

Pre-eclampsia is the most common complication occurring during pregnancy. In the majority of cases, it is concurrent with other pathologies in a comorbid manner (frequent co-occurrences in patients), such as diabetes mellitus, gestational diabetes and obesity. Providing bronchial ...

Last Updated: 17 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 101 free, full-text review articles on human participants. First 3 results:

Serum screening in first trimester to predict pre-eclampsia, small for gestational age and preterm delivery: systematic review and meta-analysis.
 

Author(s): Yan Zhong, Fufan Zhu, Yiling Ding

Journal:

 

Early assessment before the establishment of placental dysfunction has the potential to improve treatment and prognosis for clinical practice.The objective of the study is to investigate the accuracy of serum biochemical markers(Pregnancy- Associated Plasma Protein-A (PAPP-A), human ...

Last Updated: 25 Aug 2015

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Implementation of the sFlt-1/PlGF ratio for prediction and diagnosis of pre-eclampsia in singleton pregnancy: implications for clinical practice.
 

Author(s): H Stepan, I Herraiz, D Schlembach, S Verlohren, S Brennecke, F Chantraine, E Klein, O Lapaire, E Llurba, A Ramoni, M Vatish, D Wertaschnigg, A Galindo

Journal: Ultrasound Obstet Gynecol. 2015 Mar;45(3):241-6.

 

Last Updated: 4 Mar 2015

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Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm?
 

Author(s): Asif Ahmed, Wenda Ramma

Journal: Br. J. Pharmacol.. 2015 Mar;172(6):1574-86.

 

Pre-eclampsia is a vascular disorder of pregnancy where anti-angiogenic factors, systemic inflammation and oxidative stress predominate, but none can claim to cause pre-eclampsia. This review provides an alternative to the 'two-stage model' of pre-eclampsia in which abnormal spiral ...

Last Updated: 18 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Community Level Interventions for Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia; Hypertension, Pregnancy Induced

 

Last Updated: 27 Aug 2015

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The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia; Eclampsia

 

Last Updated: 16 Mar 2014

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Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers
 

Status: Recruiting

Condition Summary: Pre-eclampsia; Intra-uterine Growth Restriction

 

Last Updated: 28 Sep 2015

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