Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 935 free, full-text research articles on human participants. First 3 results:

Folic Acid Supplementation in Pregnancy and the Risk of Pre-Eclampsia-A Cohort Study.
 

Author(s): Shi Wu Wen, Yanfang Guo, Marc Rodger, Ruth Rennicks White, Qiuying Yang, Graeme N Smith, Sherry L Perkins, Mark C Walker

Journal:

 

This prospective cohort study designed to assess the effect of folic acid supplementation in pregnancy on the risk of preeclampsia (PE) took place in Ottawa, ON and Kingston, ON, Canada, from September 1, 2002 to August 31, 2008. Pregnant women, less than 20 weeks gestational age ...

Last Updated: 23 Feb 2016

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Endocan of the maternal placenta tissue is increased in pre-eclampsia.
 

Author(s): Xinwen Chang, Yiding Bian, Yanming Wu, Yajing Huang, Kai Wang, Tao Duan

Journal:

 

Pre-eclampsia (PE) is associated with intravascular inflammation and endothelial dysfunction. Interestingly, endocan plays a predominant role in the vascular inflammation and is considered as a biomarker of endothelial dysfunction. The aim of this study was to explore whether the ...

Last Updated: 29 Jan 2016

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KIR2DL4 expression rather than its single nucleotide polymorphisms correlates with pre-eclampsia.
 

Author(s): Dandan Wang, Yuan Tian, Yanhui Zhao, Lianlian Liu, Xianying Liu, Fuju Wu

Journal:

 

To evaluate the single nucleotide polymorphisms and expression of KIR2DL4 (killer cell immunoglobulin-like receptors) gene in pre-eclampsia patients.

Last Updated: 29 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 116 free, full-text review articles on human participants. First 3 results:

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies.
 

Author(s): Emily Bartsch, Karyn E Medcalf, Alison L Park, Joel G Ray,

Journal:

 

To develop a practical evidence based list of clinical risk factors that can be assessed by a clinician at ≤ 16 weeks' gestation to estimate a woman's risk of pre-eclampsia.

Last Updated: 20 Apr 2016

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Prevalence of Preeclampsia and Eclampsia in Iran.
 

Author(s): Roghieh Kharaghani, Zahra Cheraghi, Batool Okhovat Esfahani, Zahra Mohammadian, Reyhaneh Sadat Nooreldinc

Journal: Arch Iran Med. 2016 Jan;19(1):64-71.

 

Several studies have been conducted to investigate the prevalence of preeclampsia and eclampsia in Iran. These studies have yielded different results. This meta-analysis was aimed to estimate the prevalence of preeclampsia and eclampsia in Iran.

Last Updated: 25 Dec 2015

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Clinical pharmacokinetic properties of magnesium sulphate in women with pre-eclampsia and eclampsia.
 

Author(s): B O Okusanya, O T Oladapo, Q Long, P Lumbiganon, G Carroli, Z Qureshi, L Duley, J P Souza, A M Gülmezoglu

Journal: BJOG. 2016 Feb;123(3):356-66.

 

The pharmacokinetic basis of magnesium sulphate (MgSO4 ) dosing regimens for eclampsia prophylaxis and treatment is not clearly established.

Last Updated: 26 Jan 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

CA-125 and Severity of Pre-Eclampsia
 

Status: Not yet recruiting

Condition Summary: Pre-Eclampsia

 

Last Updated: 17 Mar 2016

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Saccadic Reaction Time and Preterm Pre-eclampsia
 

Status: Not yet recruiting

Condition Summary: Pre-eclampsia

 

Last Updated: 22 Nov 2015

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Phenylephrine Versus Ephedrine in Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia

 

Last Updated: 8 Jul 2016

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