Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 598 free, full-text research articles on human participants. First 3 results:

Ruptured subcapsular hematoma of the liver due to pre-eclampsia presenting as interstitial pregnancy and the role of intra-abdominal packing.
 

Author(s): N C Ngene, N Amin, J Moodley

Journal: Niger J Clin Pract. ;18(2):300-3.

 

Ruptured subcapsular hematoma of the liver (RSHL) can mimic ruptured interstitial pregnancy because each of these conditions occasionally presents at the same gestational period and both do manifest hemodynamic instability. The similarities between the two conditions pose a diagnostic ...

Last Updated: 10 Feb 2015

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Doppler flowmetry of ophthalmic arteries for prediction of pre-eclampsia.
 

Author(s): Larissa Oliveira de Aquino, Henrique Vítor Leite, Antônio Carlos Vieira Cabral, Augusto Henriques F Brandão

Journal: Rev Assoc Med Bras. ;60(6):538-41.

 

central nervous system (CNS) hyperperfusion is one of the events that constitute the pathophysiological basis for the clinical manifestations and complications of pre-eclampsia (PE). Detecting the increased flow in the CNS through Doppler flowmetry of the ophthalmic artery might precede ...

Last Updated: 5 Feb 2015

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A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia.
 

Author(s): Annettee Nakimuli, Olympe Chazara, Susan E Hiby, Lydia Farrell, Stephen Tukwasibwe, Jyothi Jayaraman, James A Traherne, John Trowsdale, Francesco Colucci, Emma Lougee, Robert W Vaughan, Alison M Elliott, Josaphat Byamugisha, Pontiano Kaleebu, Florence Mirembe, Neda Nemat-Gorgani, Peter Parham, Paul J Norman, Ashley Moffett

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2015 Jan;112(3):845-50.

 

In sub-Saharan Africans, maternal mortality is unacceptably high, with >400 deaths per 100,000 births compared with <10 deaths per 100,000 births in Europeans. One-third of the deaths are caused by pre-eclampsia, a syndrome arising from defective placentation. Controlling placentation ...

Last Updated: 21 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 81 free, full-text review articles on human participants. First 3 results:

The association between dietary factors and gestational hypertension and pre-eclampsia: a systematic review and meta-analysis of observational studies.
 

Author(s): Danielle A J M Schoenaker, Sabita S Soedamah-Muthu, Gita D Mishra

Journal:

 

Dietary factors have been suggested to play a role in the prevention of hypertensive disorders of pregnancy (HDP), including gestational hypertension and pre-eclampsia, but inconsistent findings have been reported. A systematic review and meta-analyses were performed to synthesize ...

Last Updated: 24 Jan 2015

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Pre-eclampsia renamed and reframed: Intra-abdominal hypertension in pregnancy.
 

Author(s): Diane J Sawchuck, Bernd K Wittmann

Journal: Med. Hypotheses. 2014 Nov;83(5):619-32.

 

This hypothesis proposes pre-eclampsia is caused by intra-abdominal hypertension in pregnancy. Sustained or increasing intra-abdominal pressure ⩾12mmHg causes impaired venous return to the heart, systemic vascular resistance, ischemia reperfusion injury, intestinal permeability, ...

Last Updated: 2 Dec 2014

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TH17 cells in human recurrent pregnancy loss and pre-eclampsia.
 

Author(s): Binqing Fu, Zhigang Tian, Haiming Wei

Journal: Cell. Mol. Immunol.. 2014 Nov;11(6):564-70.

 

T helper 17 (TH17) cells have been identified as a new lineage of helper T cells and have been shown to be important in host defense against extracellular infectious agents, autoimmune disease and chronic inflammatory diseases. Recently, TH17 cells have also been shown to participate ...

Last Updated: 3 Nov 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Community Level Interventions for Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia; Hypertension, Pregnancy Induced

 

Last Updated: 27 Aug 2015

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The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia; Eclampsia

 

Last Updated: 16 Mar 2014

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Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers
 

Status: Recruiting

Condition Summary: Pre-eclampsia; Intra-uterine Growth Restriction

 

Last Updated: 8 Apr 2015

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