Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 992 free, full-text research articles on human participants. First 3 results:

Determinants of magnesium sulphate use in women hospitalized at <29 weeks with severe or non-severe pre-eclampsia.
 

Author(s): Dane A De Silva, Lily Proctor, Peter von Dadelszen, Meghan McCoach, Tang Lee, , Laura A Magee

Journal:

 

Magnesium sulphate is recommended by international guidelines to prevent eclampsia among women with pre-eclampsia, especially when it is severe, but fewer than 70% of such women receive magnesium sulphate. We aimed to identify variables that prompt Canadian physicians to administer ...

Last Updated: 31 Dec 1969

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Eclampsia in rural Nigeria: The unmitigating catastrophe.
 

Author(s): Chidi Ochu Uzoma Esike, Ukaegbe Ikechi Chukwuemeka, Okechukwu Bonaventure Anozie, Justus Ndulue Eze, Obioma Christian Aluka, Deirdre Eilleen Twomey

Journal: Ann Afr Med. ;16(4):175-180.

 

Eclampsia is one of the most dreaded causes of adverse outcomes of pregnancy worldwide. It is one of the greatest causes of maternal and perinatal morbidity and mortality world over. We do not know the prevalence, management outcome, and the devastation caused by this dreaded disease ...

Last Updated: 31 Dec 1969

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First-trimester smoking cessation in pregnancy did not increase the risk of preeclampsia/eclampsia: A Murmansk County Birth Registry study.
 

Author(s): Olga A Kharkova, Andrej M Grjibovski, Alexandra Krettek, Evert Nieboer, Jon Ø Odland

Journal:

 

Although prior studies have shown that smoking reduces preeclampsia/eclampsia risk, the consequence of giving up this habit during pregnancy should be assessed. The aims of the current study were threefold: (i) describe maternal characteristics of women with preeclampsia/eclampsia; ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 122 free, full-text review articles on human participants. First 3 results:

[Haemorrhagic stroke of the brainstem secondary to postpartum eclampsia: about a case and literature review].
 

Author(s): Khadija Ennaqui, Assia Makayssi, Houssine Boufettal, Naima Samouh

Journal:

 

Strokes are rare but severe accidents during pregnancy and post-partum period. They are responsible for high mortality and morbidity rates. Pre-eclampsia, eclampsia, and strokes are significantly related. Endothelial dysfunction, alteration of brain self-regulation and severe hypertension ...

Last Updated: 31 Dec 1969

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Elucidating the Pathogenesis of Pre-eclampsia Using In Vitro Models of Spiral Uterine Artery Remodelling.
 

Author(s): Ross McNally, Abdelrahim Alqudah, Danilo Obradovic, Lana McClements

Journal:

 

The aim of the study is to perform a critical assessment of in vitro models of pre-eclampsia using complementary human and cell line-based studies. Molecular mechanisms involved in spiral uterine artery (SUA) remodelling and trophoblast functionality will also be discussed.

Last Updated: 31 Dec 1969

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Relevance of Haemodynamics in Treating Pre-eclampsia.
 

Author(s): Christoph Lees, Enrico Ferrazzi

Journal:

 

Blood pressure is a way of describing the end result of changes in cardiac output, intravascular volume and peripheral resistance. It has certain advantages in that it is a reproducible and easily measured parameter, but in itself, it offers only a limited understanding of the underlying ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Sildenafil Citrate in Management of Mild Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-Eclampsia; Mild

 

Last Updated: 24 Aug 2017

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Saccadic Reaction Time and Preterm Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia

 

Last Updated: 3 Apr 2017

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Podocyturia as Predictive Factor for Pre-eclampsia
 

Status: Not yet recruiting

Condition Summary: Pre-Eclampsia

 

Last Updated: 17 Oct 2017

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