Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 574 free, full-text research articles on human participants. First 3 results:

Post-partum trend in blood pressure levels, renal function and proteinuria in women with severe preeclampsia and eclampsia in Sub-Saharan Africa: a 6-months cohort study.
 

Author(s): Francois Folefack Kaze, Francis A Njukeng, Andre-Pascal Kengne, Gloria Ashuntantang, Robinson Mbu, Marie Patrice Halle, Tazoacha Asonganyi

Journal:

 

Preeclampsia and eclampsia, which are the most frequent hypertensive disorders in pregnancy, are associated with renal involvements. We aimed to assess the time trend in blood pressure levels, renal function and proteinuria after delivery, and investigate their determinants in Cameroonian ...

Last Updated: 30 Apr 2014

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Effect of selenium on markers of risk of pre-eclampsia in UK pregnant women: a randomised, controlled pilot trial.
 

Author(s): Margaret P Rayman, Elizabeth Searle, Lynne Kelly, Sigurd Johnsen, Katherine Bodman-Smith, Sarah C Bath, Jinyuan Mao, Christopher W G Redman

Journal: Br. J. Nutr.. 2014 Jul;112(1):99-111.

 

Pre-eclampsia is a serious hypertensive condition of pregnancy associated with high maternal and fetal morbidity and mortality. Se intake or status has been linked to the occurrence of pre-eclampsia by our own work and that of others. We hypothesised that a small increase in the Se ...

Last Updated: 13 Jun 2014

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Adverse neonatal outcomes in women with pre-eclampsia in Mulago Hospital, Kampala, Uganda: a cross-sectional study.
 

Author(s): Paul Kiondo, Nazarius Mbona Tumwesigye, Julius Wandabwa, Gakenia Wamuyu-Maina, Gabriel S Bimenya, Pius Okong

Journal:

 

Pre-eclampsia, which is more prevalent in resource-limited settings, contributes significantly to maternal, fetal and neonatal morbidity and mortality. However, the factors associated with these adverse outcomes are poorly understood in low resource settings. In this paper we examine ...

Last Updated: 19 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 74 free, full-text review articles on human participants. First 3 results:

Low-dose calcium supplementation for preventing pre-eclampsia: a systematic review and commentary.
 

Author(s): G J Hofmeyr, J M Belizán, P von Dadelszen,

Journal: BJOG. 2014 Jul;121(8):951-7.

 

Epidemiological data link low dietary calcium with pre-eclampsia. Current recommendations are for 1.5-2 g/day calcium supplementation for low-intake pregnant women, based on randomised controlled trials of ≥1 g/day calcium supplementation from 20 weeks of gestation. This is problematic ...

Last Updated: 24 Jun 2014

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Vitamin D and pre-eclampsia: original data, systematic review and meta-analysis.
 

Author(s): Elina Hyppönen, Alana Cavadino, David Williams, Abigail Fraser, Attila Vereczkey, William D Fraser, Ferenc Bánhidy, Deborah Lawlor, Andrew E Czeizel

Journal: Ann. Nutr. Metab.. 2013 ;63(4):331-40.

 

Vitamin D may protect from pre-eclampsia through influences on immune modulation and vascular function. To evaluate the role of vitamin D in the development of pre-eclampsia, we conducted a systematic review and meta-analysis including novel data from 2 large-scale epidemiological studies.

Last Updated: 25 Mar 2014

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[Uric acid and purine plasma levels as plausible markers for placental dysfunction in pre-eclampsia].
 

Author(s): Carlos Escudero, Patricio Bertoglia, Felipe Muñoz, James M Roberts

Journal: Rev Med Chil. 2013 Jul;141(7):895-902.

 

Uric acid is the final metabolite of purine break down, such as ATP, ADP, AMP, adenosine, inosine and hypoxanthine. The metabolite has been used broadly as a renal failure marker, as well as a risk factor for maternal and neonatal morbidity during pre-eclamptic pregnancies. High purine ...

Last Updated: 20 Dec 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Community Level Interventions for Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia; Hypertension, Pregnancy Induced

 

Last Updated: 25 Sep 2014

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The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia
 

Status: Recruiting

Condition Summary: Preeclampsia; Eclampsia

 

Last Updated: 16 Mar 2014

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Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers
 

Status: Recruiting

Condition Summary: Pre-eclampsia; Intra-uterine Growth Restriction

 

Last Updated: 1 Oct 2013

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