Congenital adrenal hyperplasia

Common Name(s)

Congenital adrenal hyperplasia, Adrenogenital syndrome

Adrenogenital syndrome, also called congenital adrenal hyperplasia (CAH), is a group of genetic disorders. These conditions cause various abnormalities in the adrenal glands and a person’s hormones, which are a chemical produced in the adrenal glands and used to send signals throughout the body. In these conditions, some hormones are unable to be produced and some are also overproduced. This can result in high blood pressure and electrolyte abnormalities in infants born with this condition. It can also cause abnormal genitalia development in both males and females. Patients are usually diagnosed with these conditions at birth or when delayed puberty is apparent. These conditions can be controlled using steroid replacements, although underdevelopment of male genitalia is often permanent and requires specialist involvement.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital adrenal hyperplasia" for support, advocacy or research.

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National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

Last Updated: 13 Oct 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital adrenal hyperplasia" for support, advocacy or research.

Logo
National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

http://www.nadf.us

Last Updated: 13 Oct 2014

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Congenital adrenal hyperplasia" returned 281 free, full-text research articles on human participants. First 3 results:

Images in clinical medicine. Congenital adrenal hyperplasia.
 

Author(s): Po-Jui Ko, Ming-Lun Yeh

Journal: N. Engl. J. Med.. 2015 Jun;372(24):e32.

 

Last Updated: 11 Jun 2015

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Ten-year evaluation of a Neonatal Screening Program for congenital adrenal hyperplasia.
 

Author(s): Marilza Leal Nascimento, Anísia Nhelety Baptista Cristiano, Tatiane de Campos, Masanao Ohira, Edson Cechinel, Genoir Simoni, Juliana van de Sande Lee, Rose Marie Muller Linhares, Paulo Cesar Alves da Silva

Journal: Arq Bras Endocrinol Metabol. 2014 Oct;58(7):765-71.

 

Evaluate the Neonatal Screening Program (NSP) for congenital adrenal hyperplasia (CAH) of the Department of Health of the State of Santa Catarina (Secretaria de Estado da Saúde de Santa Catarina, SES/SC), and provide information to improve the program.

Last Updated: 6 Nov 2014

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Late-onset congenital adrenal hyperplasia with Cushing syndrome.
 

Author(s): Gurbuz Erdogan, Recai Pabuccu, Sibel Ertek, Shoshana Israel, Banu Yilmaz, Hilal Yilmaz, Gamze Caglar

Journal: Intern. Med.. 2014 ;53(17):1955-9.

 

Although hirsutism is classically part of the clinical presentation of polycystic ovarian syndrome (PCOS), congenital adrenal hyperplasia and Cushing's syndrome (CS), CS associated with underlying late-onset congenital adrenal hyperplasia (LCAH) in an adult has not been previously ...

Last Updated: 1 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Congenital adrenal hyperplasia" returned 31 free, full-text review articles on human participants. First 3 results:

The role of imaging in congenital adrenal hyperplasia.
 

Author(s): Sara Reis Teixeira, Paula Condé Lamparelli Elias, Marco Túlio Soares Andrade, Andrea Farias Melo, Jorge Elias Junior

Journal: Arq Bras Endocrinol Metabol. 2014 Oct;58(7):701-8.

 

Congenital adrenal hyperplasia (CAH) is an autossomic recessive disorder caused by impaired steroidogenesis. Patients with CAH may present adrenal insufficiency with or without salt-wasting, as well as various degrees of virilization and fertility impairment, carrying a high incidence ...

Last Updated: 6 Nov 2014

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[Congenital adrenal hyperplasia in the adult women: management of old and new challenges].
 

Author(s): Flávia A Costa-Barbosa, Mariana Telles-Silveira, Claudio E Kater

Journal: Arq Bras Endocrinol Metabol. 2014 Mar;58(2):124-31.

 

Due to major improvements in the management and therapy of patients with congenital adrenal hyperplasia owing to 21-hydroxylase deficiency (21OHD) along childhood and adolescence, affected women are able to reach adulthood. Therefore, management throughout adult life became even more ...

Last Updated: 16 May 2014

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Physiological basis for the etiology, diagnosis, and treatment of adrenal disorders: Cushing's syndrome, adrenal insufficiency, and congenital adrenal hyperplasia.
 

Author(s): Hershel Raff, Susmeeta T Sharma, Lynnette K Nieman

Journal: Compr Physiol. 2014 Apr;4(2):739-69.

 

The hypothalamic-pituitary-adrenal (HPA) axis is a classic neuroendocrine system. One of the best ways to understand the HPA axis is to appreciate its dynamics in the variety of diseases and syndromes that affect it. Excess glucocorticoid activity can be due to endogenous cortisol ...

Last Updated: 9 Apr 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cardiovascular Risk Profile in Patients With Congenital Adrenal Hyperplasia
 

Status: Recruiting

Condition Summary: Congenital Adrenal Hyperplasia

 

Last Updated: 23 Apr 2015

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Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia
 

Status: Recruiting

Condition Summary: Adrenal Insufficiency; Excess Androgen; Congenital Adrenal Hyperplasia (CAH)

 

Last Updated: 10 Mar 2015

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Adrenocortical Functions in Women With Nonclassical 21-hydroxylase Deficiency.
 

Status: Recruiting

Condition Summary: Adrenal Hyperplasia, Congenital; 21-hydroxylase Deficiency

 

Last Updated: 11 Mar 2015

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