Dystonia

Common Name(s)

Dystonia

Dystonia is a condition that causes your muscles to spontaneously contract, or movement without control. Examples include: uncontrolled blinking, repetitive twisting of your head, and voice changes (e.g. whispering or soft voice). Dystonia can be caused by dysfunction in nerve cell communication, or the way your brain communicates with your muscles, as well as other disease such as Parkinson's disorder, Huntington's disease, strokes, brain tumors. Side effects of dystonia include pain, difficulty with jaw movement or functional blindness. Treatment for dystonia can include oral medications, physical therapy,speech therapy, brain stimulation. There are also alternative medicine options such as yoga, meditation, pilates that can be done at home.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dystonia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

View Details
Logo
Dystonia Medical Research Foundation

The mission of the DMRF is to advance research for more effective treatments and ultimately a cure for dystonia, to promote awareness and education, and to support the well being of dystonia affected individuals and families.

Last Updated: 29 Oct 2012

View Details
Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

Last Updated: 5 May 2014

View Details
National Spasmodic Dysphonia Association

The mission of the National Spasmodic Dysphonia Association is to advance medical research into the causes of and treatments for spasmodic dysphonia, promote physician and public awareness of the disorder, and provide support to those affected by spasmodic dysphonia.

Last Updated: 9 Nov 2012

View Details
The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dystonia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

View Details
Logo
Dystonia Medical Research Foundation

The mission of the DMRF is to advance research for more effective treatments and ultimately a cure for dystonia, to promote awareness and education, and to support the well being of dystonia affected individuals and families.

http://www.dystonia-foundation.org

Last Updated: 29 Oct 2012

View Details
Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

http://www.movementdisorders.org/MDS.htm

Last Updated: 5 May 2014

View Details
National Spasmodic Dysphonia Association

The mission of the National Spasmodic Dysphonia Association is to advance medical research into the causes of and treatments for spasmodic dysphonia, promote physician and public awareness of the disorder, and provide support to those affected by spasmodic dysphonia.

http://www.dysphonia.org/

Last Updated: 9 Nov 2012

View Details
The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

https://www.dystonia-parkinson.org

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dystonia" returned 693 free, full-text research articles on human participants. First 3 results:

Long-term neuropsychiatric outcomes after pallidal stimulation in primary and secondary dystonia.
 

Author(s): Sara Meoni, Mateusz Zurowski, Andres M Lozano, Mojgan Hodaie, Yu-Yan Poon, Melanie Fallis, Valerie Voon, Elena Moro

Journal: Neurology. 2015 Aug;85(5):433-40.

 

To evaluate changes in the diagnosis of Axis I psychiatric disorders in patients with primary and secondary dystonia after deep brain stimulation (DBS) of the globus pallidus internus (GPi).

Last Updated: 5 Aug 2015

Go To URL
Efficacy of aripiprazole in antidepressants-induced tardive dystonia and tardive dyskinesia: a case report.
 

Author(s): Lyang Huh, Bong Ju Lee

Journal: Psychiatr Danub. 2015 Jun;27(2):195-7.

 

Last Updated: 10 Jun 2015

Go To URL
A missense mutation in KCTD17 causes autosomal dominant myoclonus-dystonia.
 

Author(s): Niccolo E Mencacci, Ignacio Rubio-Agusti, Anselm Zdebik, Friedrich Asmus, Marthe H R Ludtmann, Mina Ryten, Vincent Plagnol, Ann-Kathrin Hauser, Sara Bandres-Ciga, Conceição Bettencourt, Paola Forabosco, Deborah Hughes, Marc M P Soutar, Kathryn Peall, Huw R Morris, Daniah Trabzuni, Mehmet Tekman, Horia C Stanescu, Robert Kleta, Miryam Carecchio, Giovanna Zorzi, Nardo Nardocci, Barbara Garavaglia, Ebba Lohmann, Anne Weissbach, Christine Klein, John Hardy, Alan M Pittman, Thomas Foltynie, Andrey Y Abramov, Thomas Gasser, Kailash P Bhatia, Nicholas W Wood

Journal: Am. J. Hum. Genet.. 2015 Jun;96(6):938-47.

 

Myoclonus-dystonia (M-D) is a rare movement disorder characterized by a combination of non-epileptic myoclonic jerks and dystonia. SGCE mutations represent a major cause for familial M-D being responsible for 30%-50% of cases. After excluding SGCE mutations, we identified through ...

Last Updated: 6 Jun 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dystonia" returned 91 free, full-text review articles on human participants. First 3 results:

The expanding spectrum of neurological phenotypes in children with ATP1A3 mutations, Alternating Hemiplegia of Childhood, Rapid-onset Dystonia-Parkinsonism, CAPOS and beyond.
 

Author(s): Matthew T Sweney, Tara M Newcomb, Kathryn J Swoboda

Journal: Pediatr. Neurol.. 2015 Jan;52(1):56-64.

 

ATP1A3 mutations have now been recognized in infants and children presenting with a diverse group of neurological phenotypes, including Rapid-onset Dystonia-Parkinsonism (RDP), Alternating Hemiplegia of Childhood (AHC), and most recently, Cerebellar ataxia, Areflexia, Pes cavus, Optic ...

Last Updated: 23 Dec 2014

Go To URL
Diagnosis and treatment of dystonia.
 

Author(s): H A Jinnah, Stewart A Factor

Journal: Neurol Clin. 2015 Feb;33(1):77-100.

 

The dystonias are a group of disorders characterized by excessive involuntary muscle contractions leading to abnormal postures and/or repetitive movements. A careful assessment of the clinical manifestations is helpful for identifying syndromic patterns that focus diagnostic testing ...

Last Updated: 29 Nov 2014

Go To URL
Shock waves in the treatment of muscle hypertonia and dystonia.
 

Author(s): Laura Mori, Lucio Marinelli, Elisa Pelosin, Antonio Currà, Luigi Molfetta, Giovanni Abbruzzese, Carlo Trompetto

Journal: Biomed Res Int. 2014 ;2014():637450.

 

Since 1997, focused shock waves therapy (FSWT) has been reported to be useful in the treatment of muscle hypertonia and dystonia. More recently, also radial shock wave therapy (RSWT) has been successfully used to treat muscle hypertonia. The studies where FSWT and RSWT have been used ...

Last Updated: 13 Oct 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison of Electrophysiologic and Ultrasound Guidance for Onabotulinum Toxin A Injections in Focal Upper Extremity Dystonia and Spasticity
 

Status: Recruiting

Condition Summary: Dystonia; Focal Dystonia; Musician's Dystonia; Muscle Spasticity

 

Last Updated: 12 Jan 2016

Go to URL
Neuroimaging of Dystonia
 

Status: Recruiting

Condition Summary: Primary Cervical Dystonia; DYT 1 Dystonia

 

Last Updated: 30 Nov 2015

Go to URL
Novel Stimulation Patterns for the Treatment of Dystonia
 

Status: Recruiting

Condition Summary: Dystonia; Cervical Dystonia

 

Last Updated: 11 Sep 2015

Go to URL