Adrenocortical Carcinoma

Common Name(s)

Adrenocortical Carcinoma

Adrenocortical carcinoma is a rare cancer, which comes from the adrenal gland. There are two adrenal glands in the human body, one on the top of each kidney in the abdomen. They are shaped like triangles, and each is about a ½ inch high and 3 inches long.

There are two main types of adrenocortical cancer:

Functioning is the most common type and accounts for about 70 percent of adrenal cancers. These tumors are "functioning" because they make hormones, which may have various effects on the body such as facial hair growth, increased blood pressure, or weight gain.

Non-functioning tumors do not produce hormones.

Adrenocortical carcinoma is a rare cancer, affecting only about 300 to 500 people each year in the United States.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adrenocortical Carcinoma" for support, advocacy or research.

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National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

Last Updated: 13 Oct 2014

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NET Patient Foundation

The Charity’s objects (“the Objects”) are: 1. to advance the education of the general public (including relevant medical and scientific communities) in all areas relating to NETs. 2. to promote the physical and mental health of those affected by NETs through the provision of support, advice and education to patients, their carers and family members.

Last Updated: 9 Nov 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adrenocortical Carcinoma" for support, advocacy or research.

Logo
National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

http://www.nadf.us

Last Updated: 13 Oct 2014

View Details
Logo
NET Patient Foundation

The Charity’s objects (“the Objects”) are: 1. to advance the education of the general public (including relevant medical and scientific communities) in all areas relating to NETs. 2. to promote the physical and mental health of those affected by NETs through the provision of support, advice and education to patients, their carers and family members.

http://www.netpatientfoundation.org

Last Updated: 9 Nov 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Adrenocortical Carcinoma" returned 224 free, full-text research articles on human participants. First 3 results:

Beyond biology: the impact of marital status on survival of patients with adrenocortical carcinoma.
 

Author(s): Zachary Klaassen, Lael Reinstatler, Martha K Terris, Willie Underwood, Kelvin A Moses

Journal: Int Braz J Urol. ;41(6):1108-15.

 

To analyze the association of marital status and survival of patients with ACC using a population-based database.

Last Updated: 8 Jan 2016

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First Case Report of a Sporadic Adrenocortical Carcinoma With Gastric Metastasis and a Synchronous Gastrointestinal Stromal Tumor of the Stomach.
 

Author(s): Attila Kovecsi, Ioan Jung, Tivadar Bara, Tivadar Bara, Leonard Azamfirei, Zsolt Kovacs, Simona Gurzu

Journal: Medicine (Baltimore). 2015 Sep;94(37):e1549.

 

Adrenocortical carcinoma is a rare tumor with high aggresivity that can associate systemic metastases. A 71-year-old man was hospitalized for gastric cancer. The abdominal computed tomography also revealed a tumor above the right kidney. Total gastrectomy and right adrenalectomy were ...

Last Updated: 17 Sep 2015

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Incidence and Risk Factors Associated with Readmission After Surgical Treatment for Adrenocortical Carcinoma.
 

Author(s): Javier Valero-Elizondo, Yuhree Kim, Jason D Prescott, Georgios A Margonis, Thuy B Tran, Lauren M Postlewait, Shishir K Maithel, Tracy S Wang, Jason A Glenn, Ioannis Hatzaras, Rivfka Shenoy, John E Phay, Kara Keplinger, Ryan C Fields, Linda X Jin, Sharon M Weber, Ahmed Salem, Jason K Sicklick, Shady Gad, Adam C Yopp, John C Mansour, Quan-Yang Duh, Natalie Seiser, Carmen C Solorzano, Colleen M Kiernan, Konstantinos I Votanopoulos, Edward A Levine, George A Poultsides, Timothy M Pawlik

Journal: J. Gastrointest. Surg.. 2015 Dec;19(12):2154-61.

 

Adrenocortical carcinoma (ACC) is a rare disease with a poor prognosis. Given the lack of data on readmission after resection of ACC, the objective of the current study was to define the incidence of readmission, as well as identify risk factors associated with readmission among patients ...

Last Updated: 11 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Adrenocortical Carcinoma" returned 28 free, full-text review articles on human participants. First 3 results:

Developing treatment for adrenocortical carcinoma.
 

Author(s): T M A Kerkhofs, M H T Ettaieb, I G C Hermsen, H R Haak

Journal: Endocr. Relat. Cancer. 2015 Dec;22(6):R325-38.

 

Cancer of the adrenal cortex (ACC) is a rare endocrine malignancy with limited treatment options. Patients typically present with autonomous hormonal overproduction and/or a large abdominal mass. Hormonal assays and medical imaging can be diagnostic, but urinary steroid profiling ...

Last Updated: 13 Oct 2015

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Dissecting Morphological and Molecular Heterogeneity in Adrenocortical Carcinoma.
 

Author(s): Eleonora Duregon, Marco Volante, Ida Rapa, Simona Vatrano, Mauro Papotti

Journal: Turk Patoloji Derg. 2015 ;31 Suppl 1():98-104.

 

Adrenocortical carcinoma is generally considered a single entity by pathologists and clinicians. Nevertheless, the knowledge cumulated along the last decade on the pathological characterization, the clinical outcome and the molecular pathogenesis of adrenocortical carcinoma demonstrate ...

Last Updated: 16 Jul 2015

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Laparoscopic Adrenalectomy for Large Adrenocortical Carcinoma.
 

Author(s): Norman Oneil Machado, Hani Al Qadhi, Khalifa Al Wahaibi, Syed G Rizvi

Journal: JSLS. ;19(3):.

 

Adrenocortical cancer (ACC) is a rare disease that is difficult to treat. Laparoscopic adrenalectomy (LA) is performed, even for large adrenocortical carcinomas. However, the oncological effectiveness of LA remains unclear. This review presents the current knowledge of the feasibility ...

Last Updated: 16 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma
 

Status: Recruiting

Condition Summary: Adrenocortical Carcinoma; Adrenal Cancer; ACC

 

Last Updated: 11 May 2016

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Surgery and Heated Chemotherapy for Adrenocortical Carcinoma
 

Status: Recruiting

Condition Summary: Adrenocortical Carcinoma; Peritoneal Carcinomatosis

 

Last Updated: 11 May 2016

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German Adrenocortical Carcinoma Registry
 

Status: Recruiting

Condition Summary: Adrenocortical Carcinoma

 

Last Updated: 6 Sep 2015

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