Dyspepsia

Common Name(s)

Dyspepsia, Indigestion

Dyspepsia is discomfort or pain from the upper digestive tract, also known as indigestion. This discomfort may be originating from the stomach, throat, or upper intestine. Common symptoms of dyspepsia include bloating, nausea, loss of appetite, a burning sensation, regurgitation, and burping. Dyspepsia without the presence of another gastrointestinal (GI) condition is known as functional dyspepsia. Dyspepsia is very common and affects 15% of the Western population.

Dyspepsia may be caused by another GI condition or may be caused by specific food sensitivities or stressors. Potential causes include disorders in the movement of food through the upper GI tract, the presence of ulcers, and acid reflux disease. Certain foods, such as lactose in those who are lactose intolerant, caffeine, alcohol, or oral medications may also cause dyspepsia. Stomach or duodenal ulcers may cause dyspepsia. Depression, anxiety, and increased stress may also cause dyspepsia.

Treatment is often dependent upon the specific cause of the dyspepsia. Dietary changes such as avoidance of the foods that cause symptoms is often suggested. Behavioral changes such as eating frequent, smaller meals rather than three large meals, and not lying down after eating may also alleviate symptoms. Refraining from smoking or wearing tight fitting clothes may be beneficial, as well as maintaining a healthy body weight. Medications to decrease stomach acid or pain may also be used. Certain anti-inflammatory medications, such as ibuprofen, may cause damage to the lining of the stomach and should be minimized or avoided in individuals with dyspepsia. If you are suffering from dyspepsia, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dyspepsia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dyspepsia" returned 664 free, full-text research articles on human participants. First 3 results:

Functional Dyspepsia.
 

Author(s): Nicholas J Talley, Alexander C Ford

Journal: N. Engl. J. Med.. 2016 Mar;374(9):896.

 

Last Updated: 11 Mar 2016

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The prevalence of functional dyspepsia using Rome III questionnaire among chronic hepatitis C patients.
 

Author(s): Hala I Mohamed, Hamdy A Mokarib, Zienab M Saad, Wael M Abd El Ghany

Journal:

 

Hepatitis C virus (HCV) is a common chronic infection that is widely associated with symptoms of fatigue and abdominal pain. The aim of the present study was to determine the prevalence of functional dyspepsia (FD) among patients with hepatitis C.

Last Updated: 4 Mar 2016

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Seroprevalence and Socio-demographic Factors of Helicobacter pylori Infection in Patients with Dyspepsia in Kalibaru Primary Health Care North Jakarta.
 

Author(s): Nikko Darnindro, Ari F Syam, Achmad Fauzi, Cleopas M Rumende

Journal: Acta Med Indones. 2015 Oct;47(4):297-303.

 

to identify the seroprevalence and its association with socio-demographic factors of Helicobacter pylori infection.

Last Updated: 2 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dyspepsia" returned 104 free, full-text review articles on human participants. First 3 results:

Gene polymorphisms associated with functional dyspepsia.
 

Author(s): Anastasia Kourikou, George P Karamanolis, George D Dimitriadis, Konstantinos Triantafyllou

Journal: World J. Gastroenterol.. 2015 Jul;21(25):7672-82.

 

Functional dyspepsia (FD) is a constellation of functional upper abdominal complaints with poorly elucidated pathophysiology. However, there is increasing evidence that susceptibility to FD is influenced by hereditary factors. Genetic association studies in FD have examined genotypes ...

Last Updated: 13 Jul 2015

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Systematic review with meta-analysis: prompt endoscopy as the initial management strategy for uninvestigated dyspepsia in Asia.
 

Author(s): S L Chen, K A Gwee, J S Lee, H Miwa, H Suzuki, P Guo, Y T Hao, M H Chen

Journal: Aliment. Pharmacol. Ther.. 2015 Feb;41(3):239-52.

 

Prompt endoscopy should be considered as an initial strategy for uninvestigated dyspepsia in the background of high prevalence of Helicobacter pylori infection and malignancy. However, with changes of disease patterns and dyspepsia definition, the prevalence of organic lesions at ...

Last Updated: 7 May 2015

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Systematic review with meta-analysis: post-infectious functional dyspepsia.
 

Author(s): S Futagami, T Itoh, C Sakamoto

Journal: Aliment. Pharmacol. Ther.. 2015 Jan;41(2):177-88.

 

The prevalence of functional dyspepsia (FD) following infectious gastroenteritis has not been systematically reviewed.

Last Updated: 16 Dec 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Motilitone to Treat Functional Dyspepsia
 

Status: Recruiting

Condition Summary: Dyspepsia

 

Last Updated: 15 Aug 2016

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Efficacy of Bromopride and Simethicone Versus Bromopride in Funcional Dyspepsia
 

Status: Not yet recruiting

Condition Summary: Dyspepsia

 

Last Updated: 12 Nov 2015

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Effectiveness of tDCS for the Treatment of Functional Dyspepsia
 

Status: Recruiting

Condition Summary: Dyspepsia

 

Last Updated: 17 May 2016

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