Dubin-Johnson Syndrome

Common Name(s)

Dubin-Johnson Syndrome, Hyperbilirubinemia type 2

Dubin-Johnson syndrome is a type of hereditary hyperbilirubinemia with a relatively benign course.  Symptoms may include a yellowish color to the skin (jaundice), and a liver that is sometimes enlarged and tender.   The symptoms often do not present until puberty or adulthood. The syndrome interferes with the body's ability to move bilirubin from the liver. In most cases, treatment is not required.  
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dubin-Johnson Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dubin-Johnson Syndrome" returned 21 free, full-text research articles on human participants. First 3 results:

Dubin-Johnson syndrome with multiple liver cavernous hemangiomas: report of a familial case.
 

Author(s): Peifeng Li, Yingmei Wang, Jinmei Zhang, Ming Geng, Zengshan Li

Journal:

 

Dubin-Johnson syndrome (DJS) is a rare autosomal recessive inheritance disorder of bilirubin metabolism. Herein we reported a complicated but interesting case which is readily resulted in misdiagnosis or an indefinite diagnosis, and this is the first reported familial case of DJS ...

Last Updated: 14 Nov 2013

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Dubin-Johnson syndrome coinciding with colon cancer and atherosclerosis.
 

Author(s): Eva Sticova, Milan Elleder, Helena Hulkova, Ondrej Luksan, Martin Sauer, Irena Wunschova-Moudra, Jan Novotny, Milan Jirsa

Journal: World J. Gastroenterol.. 2013 Feb;19(6):946-50.

 

Hyperbilirubinemia has been presumed to prevent the process of atherogenesis and cancerogenesis mainly by decreasing oxidative stress. Dubin-Johnson syndrome is a rare, autosomal recessive, inherited disorder characterized by biphasic, predominantly conjugated hyperbilirubinemia with ...

Last Updated: 22 Feb 2013

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[A case of sustained cholestasis caused by acute A viral hepatitis in Dubin-Johnson syndrome].
 

Author(s): Sang Ho Ra, Se Yong Sung, Ho Yeon Jung, Jae Hwang Cha, Soon Koo Baik, Mee Yon Cho, Moon Young Kim

Journal: Korean J Gastroenterol. 2012 Apr;59(4):313-6.

 

Dubin-Johnson syndrome is a rare clinical entity. It shows intermittent symptoms such as chronic or intermittent jaundice, abdominal pain, weakness, nausea, vomiting, anorexia and diarrhea. Symptoms are precipitated or aggravated by pregnancy, alcoholism, surgical procedures and intercurrent ...

Last Updated: 30 Apr 2012

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Reviews from the PubMed Database

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The terms "Dubin-Johnson Syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.