Dosage-Sensitive Sex Reversal

Common Name(s)

Dosage-Sensitive Sex Reversal

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dosage-Sensitive Sex Reversal" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dosage-Sensitive Sex Reversal" returned 2 free, full-text research articles on human participants. First 3 results:

DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner.
 

Author(s): Junguo Zhou, Robert H Oakley, John A Cidlowski

Journal: Mol. Endocrinol.. 2008 Jul;22(7):1521-34.

 

The glucocorticoid receptor (GR) mediates virtually all actions of glucocorticoids, and the nature and magnitude of a cell's response to these steroids are determined primarily by hormone concentration and GR signaling capacity. DAX-1 (dosagesensitive sex reversal-adrenal hypoplasia ...

Last Updated: 27 Jun 2008

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Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.
 

Author(s): B K Jordan, M Mohammed, S T Ching, E Délot, X N Chen, P Dewing, A Swain, P N Rao, B R Elejalde, E Vilain

Journal: Am. J. Hum. Genet.. 2001 May;68(5):1102-9.

 

Wnt-4, a member of the Wnt family of locally acting secreted growth factors, is the first signaling molecule shown to influence the sex-determination cascade. In mice, a targeted deletion of Wnt-4 causes the masculinization of XX pups. Therefore, WNT-4, the human homologue of murine ...

Last Updated: 19 Apr 2001

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dosage-Sensitive Sex Reversal" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.