Diverticular Disease

Common Name(s)

Diverticular Disease

Diverticular disease is characterized by the formation of diverticula, or small out-pouchings and pockets, in the walls of the colon (the last segment of the gastrointestinal tract which digests and carries food through the body). There are three types of diverticular diseases: diverticulosis, diverticular bleeding, and diverticulitis. The specific causes of diverticular diseases are unknown, but they are more common in people with a low fiber diet, which leads to increased pressure in the colon resulting in pocket formation. In diverticulosis (uncomplicated diverticular disease) the pockets form but do not become infected or inflamed, and therefore no symptoms occur. Infection or inflammation of the pockets (diverticulitis) can cause abdominal (belly) pain, fever, as well as other complications that may require surgery. Diverticular bleeding results in blood in the stool and bleeding from the rectum and anus, and may also require immediate medical attention. Diverticular diseases are managed by maintaining a high fiber diet (e.g. grains, vegetables), although episodes of diverticulitis and diverticular bleeding may require antibiotics, hospitalization, and potentially surgery.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diverticular Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diverticular Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diverticular Disease" returned 211 free, full-text research articles on human participants. First 3 results:

Diverticular Disease and Colorectal Neoplasms: Association between Left Sided Diverticular Disease with Colorectal Cancers and Right Sided with Colonic Polyps.
 

Author(s): E Ru Wong, Fazean Idris, Chee Fui Chong, Pemasari Upali Telisinghe, Jackson Tan, Vui Heng Chong

Journal: Asian Pac. J. Cancer Prev.. 2016 ;17(5):2401-5.

 

Both colorectal cancer (CRC) and diverticular disease (DD) are common in the affluent West, and their prevalence is also increasing in the rest of the world with economic development. Both diseases have common epidemiologic characteristics; increasing incidence, more common with advancing ...

Last Updated: 9 Jun 2016

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Colonic Diverticula and Diverticular Disease: 10 Facts Clinicians Should Know.
 

Author(s): Anne F Peery

Journal: N C Med J. ;77(3):220-2.

 

Diverticular disease accounts for substantial health care utilization and costs. Despite this public health burden, clinical practice has been largely based on poor-quality evidence. Fortunately, there is growing interest in this neglected disease. Based on recent work, clinicians ...

Last Updated: 7 May 2016

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Comparative study of collagen deposition in the colon wall of patients operated for sigmoid diverticular disease.
 

Author(s): Mário Pantaroto, Gaspar de Jesus Lopes Filho, Clovis Antonio Lopes Pinto, Armando Antico Filho

Journal: Acta Cir Bras. 2015 Oct;30(10):715-9.

 

To investigate the deposition of collagen in the colon wall of patients with sigmoid diverticulitis.

Last Updated: 12 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diverticular Disease" returned 35 free, full-text review articles on human participants. First 3 results:

Probiotics in the Treatment of Diverticular Disease. A Systematic Review.
 

Author(s): Edith Lahner, Cristina Bellisario, Cesare Hassan, Angelo Zullo, Gianluca Esposito, Bruno Annibale

Journal: J Gastrointestin Liver Dis. 2016 Mar;25(1):79-86.

 

Diverticular disease is a common gastrointestinal condition. Low-grade inflammation and altered intestinal microbiota have been identified as factors contributing to abdominal symptoms. Probiotics may lead to symptoms improvement by modifying the gut microbiota and are promising treatments ...

Last Updated: 25 Mar 2016

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Review article: the pathophysiology and medical management of diverticulosis and diverticular disease of the colon.
 

Author(s): A Tursi, A Papa, S Danese

Journal: Aliment. Pharmacol. Ther.. 2015 Sep;42(6):664-84.

 

The incidence of diverticulosis and diverticular disease of the colon, including diverticulitis, is increasing worldwide, and becoming a significant burden on national health systems. Treatment of patients with diverticulosis and DD is generally based on high-fibre diet and antibiotics, ...

Last Updated: 17 Aug 2015

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S2k Guidlines for Diverticular Disease and Diverticulitis: Diagnosis, Classification, and Therapy for the Radiologist.
 

Author(s): A G Schreyer, G Layer,

Journal: Rofo. 2015 Aug;187(8):676-84.

 

Diverticular disease and diverticulitis represent an increasingly common disease especially in patients with advanced age. The German Society of Digestive and Metabolic Diseases (DGVS) as well as the German Society of General and Visceral Surgery (DGAV) in collaboration with the German ...

Last Updated: 29 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prophylactic Elective Clipping of Colonic Diverticula
 

Status: Recruiting

Condition Summary: Diverticular Disease

 

Last Updated: 7 Apr 2016

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Last Updated: 4 May 2016

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Bacterial Contamination in Transrectal Hybrid NOTES Sigmoidectomy
 

Status: Recruiting

Condition Summary: Diverticular Disease

 

Last Updated: 16 Jul 2015

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