Adenoid cystic carcinoma

Common Name(s)

Adenoid cystic carcinoma

Adenoid cystic carcinoma is a rare type of cancer that usually develops in the salivary glands, which are the areas of the body where saliva is produced. Although less common, adenoid cystic carcinoma can also grow inside the breasts, eyes, lungs, brain, throat, and paranasal sinuses. Cancers form when a change (mutation) in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis.

Adenoid cystic carcinoma most commonly occurs in adults between the ages of 40 and 60, although it can appear in all age groups. The most common symptom of adenoid cystic carcinoma is painless swelling on the face, neck, or mouth area. This cancer may also cause facial pain and nerve paralysis, which results in difficulty displaying facial expressions. Depending on the size of the cancer, affected individuals may also experience difficulty with vision or breathing. Diagnosis is usually made with a combination of a physical exam, imaging studies, blood tests, and other laboratory studies. Diagnosis may require a doctor to take a biopsy, or sample, of the tissue to look at under a microscope in order to determine if the cells are growing in an abnormal way.

Treatment for adenoid cystic carcinoma depends on many factors such as how large the cancer is and if it has spread to other areas of the body. If you or a family member has been diagnosed with adenoid cystic carcinoma, talk to your doctor about the most current treatment options. Support groups are also available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adenoid cystic carcinoma" for support, advocacy or research.

Adenoid Cystic Carcinoma Research Foundation

The Adenoid Cystic Carcinoma Research Foundation (ACCRF) supports research into adenoid cystic carcinoma that will accelerate the development of improved therapies and a cure for the disease.

Last Updated: 5 May 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adenoid cystic carcinoma" for support, advocacy or research.

Adenoid Cystic Carcinoma Research Foundation

The Adenoid Cystic Carcinoma Research Foundation (ACCRF) supports research into adenoid cystic carcinoma that will accelerate the development of improved therapies and a cure for the disease.

http://www.accrf.org

Last Updated: 5 May 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Adenoid cystic carcinoma" returned 366 free, full-text research articles on human participants. First 3 results:

[Four Cases Report on Primary Lung Adenoid Cystic Carcinoma].
 

Author(s): Xilan He, Jianhua Chen

Journal: Zhongguo Fei Ai Za Zhi. 2017 Nov;20(11):789-792.

 

Lung adenoid cystic carcinoma is a kind of rare lung cancer. Diagnosis and treatment is not enough understandable for them. We collected and analyzed 4 cases of lung adenoid cystic carcinoma for broadening the sight of this disease.

Last Updated: 31 Dec 1969

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Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report.
 

Author(s): Nian-Ge Xia, Yan-Yan Chen, Xin-Shi Wang, Hui-Qin Xu, Rong-Yuan Zheng

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8508.

 

Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs.

Last Updated: 31 Dec 1969

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Case report of apatinib mesylate treatment in rare advanced tracheal adenoid cystic carcinoma.
 

Author(s): Hongmei Wang

Journal: Thorac Cancer. 2017 11;8(6):729-733.

 

A 57-year-old man was admitted to our department 10 years ago, diagnosed with tracheal adenoid cystic carcinoma. After discontinuing chemotherapy and radiotherapy, the disease recurred in December 2016. Apatinib mesylate (500 mg/day) was administered and computed tomography revealed ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Adenoid cystic carcinoma" returned 45 free, full-text review articles on human participants. First 3 results:

Cervical lymph node metastasis in adenoid cystic carcinoma of the sinonasal tract, nasopharynx, lacrimal glands and external auditory canal: a collective international review.
 

Author(s):

Journal: J Laryngol Otol. 2016 Dec;130(12):1093-1097.

 

To review reports of adenoid cystic carcinomas arising in the head and neck area outside of the major salivary glands, in order to enhance the care of patients with these unusual neoplasms.

Last Updated: 31 Dec 1969

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Adenoid cystic carcinoma of the palate: case report and review of literature.
 

Author(s): Uday Shankar Yaga, Nishanth Gollamudi, Ashwini Kumar Mengji, Radhika Besta, Prashanth Panta, Bhanu Prakash, Edunuri Rajashekar

Journal:

 

Adenoid Cystic Carcinoma (ACC) is a rare tumor constitutes for less than 1% of head and neck malignancies and 10% of all salivary gland tumors. Palate is the most common site to be involved in the oral cavity followed by parotid gland and submandibular gland. They are usually asymptomatic, ...

Last Updated: 31 Dec 1969

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Adenoid cystic carcinoma: emerging role of translocations and gene fusions.
 

Author(s): Piotr T Wysocki, Evgeny Izumchenko, Juliet Meir, Patrick K Ha, David Sidransky, Mariana Brait

Journal: Oncotarget. 2016 Oct;7(40):66239-66254.

 

Adenoid cystic carcinoma (ACC), the second most common salivary gland malignancy, is notorious for poor prognosis, which reflects the propensity of ACC to progress to clinically advanced metastatic disease. Due to high long-term mortality and lack of effective systemic treatment, ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinoma

 

Last Updated: 18 Aug 2017

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Trail Evaluating Particle Therapy With or Without Apatinib for H&N Adenoid Cystic Carcinoma
 

Status: Not yet recruiting

Condition Summary: Adenoid Cystic Carcinoma

 

Last Updated: 20 Oct 2016

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Last Updated: 30 Aug 2017

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