Adenoid cystic carcinoma

Common Name(s)

Adenoid cystic carcinoma

Adenoid cystic carcinoma is a rare type of cancer that usually develops in the salivary glands, which are the areas of the body where saliva is produced. Although less common, adenoid cystic carcinoma can also grow inside the breasts, eyes, lungs, brain, throat, and paranasal sinuses. Cancers form when a change (mutation) in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis.

Adenoid cystic carcinoma most commonly occurs in adults between the ages of 40 and 60, although it can appear in all age groups. The most common symptom of adenoid cystic carcinoma is painless swelling on the face, neck, or mouth area. This cancer may also cause facial pain and nerve paralysis, which results in difficulty displaying facial expressions. Depending on the size of the cancer, affected individuals may also experience difficulty with vision or breathing. Diagnosis is usually made with a combination of a physical exam, imaging studies, blood tests, and other laboratory studies. Diagnosis may require a doctor to take a biopsy, or sample, of the tissue to look at under a microscope in order to determine if the cells are growing in an abnormal way.

Treatment for adenoid cystic carcinoma depends on many factors such as how large the cancer is and if it has spread to other areas of the body. If you or a family member has been diagnosed with adenoid cystic carcinoma, talk to your doctor about the most current treatment options. Support groups are also available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adenoid cystic carcinoma" for support, advocacy or research.

Adenoid Cystic Carcinoma Research Foundation

The Adenoid Cystic Carcinoma Research Foundation (ACCRF) supports research into adenoid cystic carcinoma that will accelerate the development of improved therapies and a cure for the disease.

Last Updated: 5 May 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Adenoid cystic carcinoma" for support, advocacy or research.

Adenoid Cystic Carcinoma Research Foundation

The Adenoid Cystic Carcinoma Research Foundation (ACCRF) supports research into adenoid cystic carcinoma that will accelerate the development of improved therapies and a cure for the disease.

http://www.accrf.org

Last Updated: 5 May 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Adenoid cystic carcinoma" returned 338 free, full-text research articles on human participants. First 3 results:

Axillary lymph node metastases in adenoid cystic carcinoma of the breast. A rare finding.
 

Author(s): D Spiliopoulos, G Mitsopoulos, S Kaptanis, C Halkias

Journal: G Chir. ;36(5):209-13.

 

Adenoid cystic carcinoma (ACC) of the breast is a rare malignant salivary-type neoplasm that has a good prognosis and represents less than 1% of all breast cancers. It is a triple negative carcinoma that presents as a painful mass. The mean age at the time of diagnosis is 50-60 years ...

Last Updated: 29 Dec 2015

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Influence of gossypol acetic acid on the growth of human adenoid cystic carcinoma ACC-M cells and the expression of DNA methyltransferase 1.
 

Author(s): Y Wu, Y-N Wei, W-Y Yue, W-F Chen, S Fu

Journal:

 

We investigated the effects of gossypol acetic acid (GAA) on the proliferation, apoptosis, and expression of DNA methyltransferase 1 (DNMT1) mRNA in human adenoid cystic carcinoma (ACC-M) cells in vitro. The proliferation and apoptosis of ACC-M cells after treatment with different ...

Last Updated: 5 Nov 2015

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Giant adenoid cystic carcinoma of the sinonasal cavity.
 

Author(s): Mohamed Mliha Touati, Haddou Ammar

Journal:

 

Last Updated: 22 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Adenoid cystic carcinoma" returned 41 free, full-text review articles on human participants. First 3 results:

Primary cutaneous adenoid cystic carcinoma of the eyelid and literature review.
 

Author(s): Deniz Turgut Coban, Muhammet Kazim Erol, Dinc Suren, Birsel Tutus

Journal: Arq Bras Oftalmol. ;78(5):323-5.

 

Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare malignant epithelial tumor most commonly observed in the scalp and skin of the chest and originating from the palpebral portion of the lacrimal gland in the orbit. Here we describe the diagnosis and treatment of a rare case ...

Last Updated: 15 Oct 2015

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Adenoid cystic carcinoma of cervix: two cases report and review of the literature.
 

Author(s): Khadija Benhayoune, Hinde El Fatemi, Abdelaziz Bannani, Abdelilah Melhouf, Toufik Harmouch

Journal:

 

Adenoid cystic carcinoma of the cervix is a rare and aggressive tumor with fatal outcome. In this paper we report two cases of primary adenoid cystic carcinoma and a review of literature. A 80 years old woman, admitted to our hospital with postmenopausal bleeding and hydrorrhea. Gynealogical ...

Last Updated: 19 Jun 2015

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Complete recovery of visual disorder following surgical resection of adenoid cystic carcinoma arising in the pterygopalatine fossa: case report and review of the literature.
 

Author(s): Wei Du, Meng Cui, Peng Li, Jiheng Wang, Ruihua Luo, Jinxing Qi, Ming Zhao, Weihua Lou

Journal: Medicine (Baltimore). 2015 Jun;94(22):e892.

 

Adenoid cystic carcinoma (ACC) arising in the pterygopalatine fossa was rare, only 3 cases have been reported. In previous literature, few authors reported whether the visual deficit could be resolved following the resection of the tumor. One patient with visual dysfunction induced ...

Last Updated: 4 Jun 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Adenoid Cystic Carcinoma, Erbitux, and Particle Therapy
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinoma

 

Last Updated: 23 Apr 2013

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Testing Lenvatinib in Patients With Adenoid Cystic Carcinoma
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinoma

 

Last Updated: 2 Jun 2016

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A Study of Apatinib in Metastatic Adenoid Cystic Carcinoma of the Head and Neck
 

Status: Not yet recruiting

Condition Summary: Adenoid Cystic Carcinoma

 

Last Updated: 14 May 2016

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