Devic Disease

Common Name(s)

Devic Disease, Neuromyelitis Optica

Devic disease, is an autoimmune disease affecting the spinal cord and optic nerves (the nerves that carry information regarding sight from the eye). In Devic disease the protective outer covering of the nerves (myelin) is lost. The syndrome can also damage nerve fibers and leave areas of broken-down tissue.   Signs and symptoms worsen with time and include optic neuritis, transverse myelitis, sensory impairment, and bladder and bowel dysfunction.  Currently there is no cure for Devic disease, but there are therapies to treat an attack while it is happening, to reduce symptoms, and to prevent relapses. In its early stages, Devic disease may be confused with multiple sclerosis.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Devic Disease" for support, advocacy or research.

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The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

Last Updated: 19 Feb 2013

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The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Devic Disease" for support, advocacy or research.

Logo
The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

http://www.guthyjacksonfoundation.org

Last Updated: 19 Feb 2013

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The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Support Organizations

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Research and Educational Symposia

Recordings of all our national and international symposia are made available for our community to learn more about rare neuro-immune diseases

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Devic Disease" returned 1 free, full-text research articles on human participants. First 3 results:

Fulminant Devic disease successfully treated by lymphocytapheresis.
 

Author(s): I Nozaki, T Hamaguchi, K Komai, M Yamada

Journal: J. Neurol. Neurosurg. Psychiatr.. 2006 Sep;77(9):1094-5.

 

Last Updated: 17 Aug 2006

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Devic Disease" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Double-masked, Placebo-controlled Study With Open Label Period to Evaluate MEDI-551 in Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders
 

Status: Not yet recruiting

Condition Summary: Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders (NMO/NMOSD)

 

Last Updated: 24 Jul 2014

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A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica; Neuromyelitis Optica Spectrum Disorder; Transverse Myelitis; Optic Neuritis

 

Last Updated: 5 Sep 2013

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Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica; Neuromyelitis Optica Spectrum Disorders

 

Last Updated: 19 Dec 2013

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