Desmoplastic Small Round Cell Tumor

Common Name(s)

Desmoplastic Small Round Cell Tumor

Desmoplastic small round cell tumors (DSRCT), a rare malignant cancer, is a soft tissue sarcoma that usually affects young boys and men and is found most often in the abdomen. Its name means that it is formed by small, round cancer cells surrounded by scarlike tissue. The most common symptoms include abdominal pain, abdominal mass and symptoms of gastrointestinal obstruction.  DSRCTs are treated first with chemotherapy, then with surgery to remove the tumor, if possible. Radiation therapy is sometimes given, depending on the tumor. In addition, some people with DSRCT are candidates for a bone marrow transplant.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Desmoplastic Small Round Cell Tumor" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Desmoplastic Small Round Cell Tumor" returned 45 free, full-text research articles on human participants. First 3 results:

Desmoplastic small round cell tumor: Diagnostic dilemma and uncertain prognosis: Report of few cases.
 

Author(s): Palash Kumar Mandal, Anindya Adhikari, Anuradha De, Santosh Kumar Mondal

Journal: J Cancer Res Ther. ;11(4):1028.

 

Desmoplastic small round cell tumor (DSRCT) is rare and highly malignant neoplasm. DSRCT affects usually young males but can occur in adults also. Intra-abdominal pelvic region is the preferred site. Though confirmed by histology, immunohistochemistry (IHC) plays a key role in diagnosis. ...

Last Updated: 17 Feb 2016

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A Case of Desmoplastic Small Round Cell Tumor.
 

Author(s): David Reisner, Deborah Brahee, Shweta Patel, Matthew Hartman

Journal:

 

Desmoplastic small round cell tumor is a rare, aggressive tumor primarily affecting young males. It is considered a childhood cancer, and is characterized by a unique chromosomal translocation which leads to failure to suppress tumor growth. It is classified as a soft tissue sarcoma, ...

Last Updated: 2 Dec 2015

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Primary desmoplastic small round cell tumor of the testis: First case in India and review of the literature.
 

Author(s): M V Manjula, Y S Pawar

Journal: J Cancer Res Ther. ;11(3):650.

 

The purpose of this study is to describe the aggressive clinical behavior of desmoplastic small round cell tumor (DSRCT) of the testis and review of the literature. A 17-year-old male having painless testicular mass and neck swelling diagnosed to have metastatic DSRCT of the testis. ...

Last Updated: 13 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Desmoplastic Small Round Cell Tumor" returned 6 free, full-text review articles on human participants. First 3 results:

Testicular desmoplastic small round cell tumor: a case report and review of literature.
 

Author(s): Gui-Ming Zhang, Yao Zhu, Hua-Lei Gan, Ding-Wei Ye

Journal:

 

Desmoplastic small round cell tumor (DSRCT) is an uncommon and highly aggressive malignancy with undetermined histogenesis and poor prognosis. To date, no case of testicular DSRCT has been reported in the literature.

Last Updated: 23 Jul 2014

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Fine-needle aspiration in desmoplastic small round cell tumor: a report of 10 new tumors in 8 patients with clinicopathological and molecular correlations with review of the literature.
 

Author(s): Jerzy Klijanienko, Pierre Colin, Jérôme Couturier, Réal Lagacé, Paul Fréneaux, Gaëlle Pierron, Marick Laé, Alice Klijanienko, Hervé Brisse, Daniel Orbach, Stamatios Theocharis

Journal: Cancer Cytopathol. 2014 May;122(5):386-93.

 

Desmoplastic small round cell tumor (DSRCT) is a rare round cell sarcoma entity characterized by a specific t(11;22)(p13;q12) translocation, usually intra-abdominal localization and an aggressive clinical outcome. To date, only 35 DSRCT cases diagnosed by fine-needle aspiration have been described.

Last Updated: 14 May 2014

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Misdiagnosed desmoplastic small round cell tumor of the pleura: case report and literature review.
 

Author(s): Zhang Jian, Huang Shaohong, Zhong Wenzhao, Gu Lijia

Journal: J. Formos. Med. Assoc.. 2014 Jan;113(1):60-1.

 

Last Updated: 21 Jan 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Understanding Communication in Healthcare to Achieve Trust (U-CHAT)
 

Status: Recruiting

Condition Summary: Neuroblastoma; Sarcoma; Carcinoma; Desmoplastic Small Round Cell Tumor; Retinoblastoma; Wilms Tumor; Melanoma; Germ Cell Tumor; Hepatoblastoma

 

Last Updated: 31 Oct 2016

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Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
 

Status: Recruiting

Condition Summary: Adult Rhabdomyosarcoma; Childhood Desmoplastic Small Round Cell Tumor; Chordoma; Desmoid Tumor; Metastatic Childhood Soft Tissue Sarcoma; Nonmetastatic Childhood Soft Tissue Sarcoma; Previously Treated Childhood Rhabdomyosarcoma; Previously Untreated Childhood Rhabdomyosarcoma; Recurrent Adult Soft Tissue Sarcoma; Recurrent Childhood Rhabdomyosarcoma; Recurrent Childhood Soft Tissue Sarcoma; Stage I Adult Soft Tissue Sarcoma; Stage II Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma

 

Last Updated: 23 Sep 2016

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