Dermatomyositis

Common Name(s)

Dermatomyositis

Dermatomyositis is one of a group of acquired muscle diseases called inflammatory myopathies (disorder of muscle tissue or muscles), which are characterized by chronic muscle inflammation accompanied by muscle weakness. The cardinal symptom is a skin rash that precedes or accompanies progressive muscle weakness.  Dermatomyositis may occur at any age, but is most common in adults in their late 40s to early 60s, or children between 5 and 15 years of age. There is no cure for dermatomyositis, but the symptoms can be treated. Options include medication, physical therapy, exercise, heat therapy (including microwave and ultrasound), orthotics and assistive devices, and rest. The cause of dermatomyositis is unknown.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatomyositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatomyositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dermatomyositis" returned 714 free, full-text research articles on human participants. First 3 results:

Multiple Oleomas Presenting as Dermatomyositis.
 

Author(s): Jalaa Zarroug, Graham R V Hughes, Christopher J Edwards

Journal: Isr. Med. Assoc. J.. 2015 Oct;17(10):644-5.

 

Last Updated: 10 Dec 2015

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Interstitial lung disease in clinically amyopathic dermatomyositis with and without anti-MDA-5 antibody: to lump or split?
 

Author(s): Satoshi Ikeda, Machiko Arita, Mitsunori Morita, Satoshi Ikeo, Akihiro Ito, Fumiaki Tokioka, Maki Noyama, Kenta Misaki, Kenji Notohara, Tadashi Ishida

Journal:

 

Interstitial lung disease (ILD) associated with clinically amyopathic dermatomyositis (CADM-ILD) is often refractory and rapidly progressive. Although the anti-melanoma differentiation-associated gene 5 (anti-MDA-5) antibody is associated with rapidly progressive ILD (RP-ILD), differences ...

Last Updated: 15 Dec 2015

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Dermatomyositis revealing breast cancer: report of a case.
 

Author(s): Safae Lamquami, Sanae Errarhay, Nisrine Mamouni, Chahrazad Bouchikhi, Abdelaziz Banani

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Dermatomyositis (DM) is a rare connective corresponding to an inflammatory disease of skeletal muscles. Paraneoplastic origin must always be sought, primarily gynecological tumor in women, but the investigations are often made difficult by the fact that a primary tumor is often not ...

Last Updated: 22 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dermatomyositis" returned 55 free, full-text review articles on human participants. First 3 results:

Polymyositis and dermatomyositis: novel insights into the pathogenesis and potential therapeutic targets.
 

Author(s): Arash H Lahouti, Lisa Christopher-Stine

Journal: Discov Med. 2015 Jun;19(107):463-70.

 

Polymyositis (PM) and dermatomyositis (DM) are the two major forms of inflammatory muscle diseases. They are characterized clinically primarily by proximal muscle weakness. The disease mechanisms that cause muscle damage and dysfunction are not fully understood. However, because of ...

Last Updated: 16 Jul 2015

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Dermatomyositis as the first manifestation of gallbladder adenocarcinoma: case report and literature overview.
 

Author(s): Petra Jurcic

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Dermatomyositis (DM) is characterized by pathognomic cutaneous manifestations (heliotrope rash, periorbital edema, Gottron's papules) and proximal muscle weakness. In this paper, I will present the case of a 48-year-old female patient whose dermatomyositis was initially diagnosed ...

Last Updated: 19 Apr 2015

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[Pneumomediastinum and cutaneous necrosis in dermatomyositis: Report of one case].
 

Author(s): Natalia Gallardo C, Omar Valenzuela L, Sebastián Ibáñez V

Journal: Rev Med Chil. 2015 Jan;143(1):120-3.

 

We report a 37 years old male with a dermatomyositis treated with oral cyclophosphamide. He was admitted to the hospital due to a zone of skin necrosis with purulent exudate, located in the second left toe. A complete blood count showed a leukocyte count of 2,600 cells/mm³. A Chest ...

Last Updated: 11 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis; Juvenile Dermatomyositis

 

Last Updated: 11 Feb 2016

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Abatacept in Juvenile Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis

 

Last Updated: 16 Nov 2015

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Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis; Polymyositis

 

Last Updated: 25 Apr 2016

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