Dermatomyositis

Common Name(s)

Dermatomyositis

Dermatomyositis is one of a group of acquired muscle diseases called inflammatory myopathies (disorder of muscle tissue or muscles), which are characterized by chronic muscle inflammation accompanied by muscle weakness. The cardinal symptom is a skin rash that precedes or accompanies progressive muscle weakness.  Dermatomyositis may occur at any age, but is most common in adults in their late 40s to early 60s, or children between 5 and 15 years of age. There is no cure for dermatomyositis, but the symptoms can be treated. Options include medication, physical therapy, exercise, heat therapy (including microwave and ultrasound), orthotics and assistive devices, and rest. The cause of dermatomyositis is unknown.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatomyositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatomyositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dermatomyositis" returned 674 free, full-text research articles on human participants. First 3 results:

Dermatomyositis Associated with Lung Neuroendocrine Carcinoma.
 

Author(s): Reina Takashima, Kazufumi Takamatsu, Yutaka Shinkawa, Masato Yagita, Motonari Fukui, Masaaki Fujita

Journal: Intern. Med.. 2017 ;56(6):719-724.

 

Dermatomyositis is associated with various types of malignancy. However, the association of dermatomyositis with lung neuroendocrine carcinoma is rare. We herein report a case of dermatomyositis with lung neuroendocrine carcinoma.

Last Updated: 21 Mar 2017

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Sex differential association of dermatomyositis with Sjögren syndrome.
 

Author(s): Chia-Chun Tseng, Shun-Jen Chang, Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Wan-Yu Sung, Ming-Chia Hsieh, Jeng-Hsien Yen

Journal: CMAJ. 2017 Feb;189(5):E187-E193.

 

Although dermatomyositis and Sjögren syndrome share serologic autoantibodies and genetic polymorphisms, population data about the incidence of Sjögren syndrome in patients with dermatomyositis is unavailable. We performed a nationwide cohort study to explore the potential relation ...

Last Updated: 1 Mar 2017

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Calcinosis in poly-dermatomyositis: clinical and laboratory predictors and treatment options.
 

Author(s): Micaela Fredi, Francesca Bartoli, Ilaria Cavazzana, Angela Ceribelli, Nice Carabellese, Angela Tincani, Minoru Satoh, Franco Franceschini

Journal: Clin. Exp. Rheumatol.. ;35(2):303-308.

 

We aimed to identify the possible clinical and laboratory predictors of calcinosis in a cohort of patients with a diagnosis of polymyositis (PM) and dermatomyositis (DM).

Last Updated: 2 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dermatomyositis" returned 56 free, full-text review articles on human participants. First 3 results:

Consensus-based recommendations for the management of juvenile dermatomyositis.
 

Author(s): Felicitas Bellutti Enders, Brigitte Bader-Meunier, Eileen Baildam, Tamas Constantin, Pavla Dolezalova, Brian M Feldman, Pekka Lahdenne, Bo Magnusson, Kiran Nistala, Seza Ozen, Clarissa Pilkington, Angelo Ravelli, Ricardo Russo, Yosef Uziel, Marco van Brussel, Janjaap van der Net, Sebastiaan Vastert, Lucy R Wedderburn, Nicolaas Wulffraat, Liza J McCann, Annet van Royen-Kerkhof

Journal: Ann. Rheum. Dis.. 2017 Feb;76(2):329-340.

 

In 2012, a European initiative called Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) was launched to optimise and disseminate diagnostic and management regimens in Europe for children and young adults with rheumatic diseases. Juvenile dermatomyositis (JDM) ...

Last Updated: 12 Aug 2016

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Clinically Amyopathic Dermatomyositis Complicated by Pleural Effusion Case Report, Literature Review, and Proposed Mechanism.
 

Author(s): Ying Wu, Sheetal Chhaya, Bert Hurowitz, Thomas Ardiles, Richard Carlson

Journal: Bull Hosp Jt Dis (2013). 2015 Jul;73(3):217-20.

 

Polymyositis-dermatomyositis (PM-DM) is a chronic inflammatory disorder that mainly involves muscles and skin. Clinically amyopathic dermatomyositis (CADM) is a unique subset of PM-DM with typical skin manifestations but little or no evidence of musculoskeletal involvement. Many cases ...

Last Updated: 5 Nov 2015

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Polymyositis and dermatomyositis: novel insights into the pathogenesis and potential therapeutic targets.
 

Author(s): Arash H Lahouti, Lisa Christopher-Stine

Journal: Discov Med. 2015 Jun;19(107):463-70.

 

Polymyositis (PM) and dermatomyositis (DM) are the two major forms of inflammatory muscle diseases. They are characterized clinically primarily by proximal muscle weakness. The disease mechanisms that cause muscle damage and dysfunction are not fully understood. However, because of ...

Last Updated: 16 Jul 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Tofacitinib in Refractory Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis

 

Last Updated: 25 Jan 2017

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Trial of IMO-8400 in Adult Patients With Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis

 

Last Updated: 30 Mar 2017

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Abatacept in Juvenile Dermatomyositis
 

Status: Recruiting

Condition Summary: Dermatomyositis

 

Last Updated: 23 Feb 2017

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