Dermatofibrosarcoma protuberans

Common Name(s)

Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans is an uncommon tumor that arises in the skin. The tumor is firm and often flesh-colored although it can be reddish, bluish, or purplish. The tumor is often found on the chest or shoulders, but it can be found on other parts of the body. Dermatofibrosarcoma protuberans may cause no symptoms, and the initial size of the tumor tends to be around 1 to 5 centimeters. This tumor has a low potential to spread to other tissues. Treatment often involves surgery to remove the tumor, such as by Mohs’ micrographic surgery. If you or a family member has been diagnosed with dermatofibrosarcoma protuberans, talk with your doctor about the most current treatment options.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatofibrosarcoma protuberans" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatofibrosarcoma protuberans" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dermatofibrosarcoma protuberans" returned 80 free, full-text research articles on human participants. First 3 results:

Dermatofibrosarcoma Protuberans: Computed Tomography and Magnetic Resonance Imaging Findings.
 

Author(s): Liang Zhang, Qing-yu Liu, Yun Cao, Jin-shuang Zhong, Wei-dong Zhang

Journal: Medicine (Baltimore). 2015 Jun;94(24):e1001.

 

The aim of this study was to analyze the computed tomography (CT) and magnetic resonance imaging (MRI) findings of dermatofibrosarcoma protuberans (DFSP), with a view to improving the diagnosis of this kind of tumor. A total of 27 cases of histopathologically confirmed DFSP were analyzed ...

Last Updated: 20 Jun 2015

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Target therapy of unresectable or metastatic dermatofibrosarcoma protuberans with imatinib mesylate: an analysis on 22 Chinese patients.
 

Author(s): Chunmeng Wang, Zhiguo Luo, Jie Chen, Biqiang Zheng, Ruming Zhang, Yong Chen, Yingqiang Shi

Journal: Medicine (Baltimore). 2015 May;94(17):e773.

 

Dermatofibrosarcoma protuberans (DFSP) is a rare, plaque-like tumor of the cutaneous tissue occurring more on the trunk than the extremities and neck. More than 95% of DFSP present anomalies on the 17q22 and 22q13 chromosomal regions leading to the fusion of COL1A1 and PDGFB genes. ...

Last Updated: 1 May 2015

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Orbital dermatofibrosarcoma protuberans with intracranial extension preceded by recurrent leiomyoma of the orbit: a case report.
 

Author(s): Sanaullah Bashir, Maryam Tariq, Hafiz Muhammad Aslam, Abdul Sattar M Hashmi, Baber Malik, Akhtar Amin, Sidra Mumtaz

Journal:

 

Dermatofibrosarcoma protuberans is a rare, locally aggressive cutaneous tumor of intermediate to low-grade malignancy. COL1A1-PDGFβ translocation is specific to dermatofibrosarcoma protuberans, where the abnormally fused COL1A1-PDGFβ gene directs formation of an abnormal combined ...

Last Updated: 7 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dermatofibrosarcoma protuberans" returned 9 free, full-text review articles on human participants. First 3 results:

[Dermatofibrosarcoma protuberans : report of 27 cases and review of the literature].
 

Author(s): Nawal Hammas, Ikram Badioui, Kaoutar Znati, Amal Benlemlih, Laila Chbani, Hind El Fatemi, Taoufiq Harmouch, Youssef Bouyahyaoui, Faouzi Boutayeb, Abdelmajid Mrini, Omar Mesbahi, Fatima Zahra Mernissi, Afaf Amarti

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Last Updated: 9 Dec 2014

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[Dermatofibrosarcoma protuberans, particular skin tumor: report of 32 cases and review of the literature].
 

Author(s): Driss Elamrani, Hatim Droussi, Samira Boukind, Keltoum Elatiqi, Meriem Dlimi, Yassine Benchamkha, Saloua Ettalbi

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Last Updated: 30 Mar 2015

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Dermatofibrosarcoma protuberans: an unusual case of neck swelling.
 

Author(s): Naeem Sultan Ali, Maliha Kazi, Beena Umar, Mumtaz Jamshed Khan

Journal: J Pak Med Assoc. 2012 Oct;62(10):1089-91.

 

Dermatofibrosarcoma protuberans (DFSP) is a relatively intermediate to low grade malignant tumour with high proclivity for local recurrence if excised inadequately. It is a locally aggressive tumour and despite sharing some histological features with fibrohistiocytic tumours, it tends ...

Last Updated: 22 Jul 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Outcome of Pediatric Dermatofibrosarcoma Protuberans
 

Status: Recruiting

Condition Summary: Soft Tissue Neoplasms

 

Last Updated: 23 Nov 2005

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Spanish Registry of Mohs Surgery
 

Status: Recruiting

Condition Summary: Skin Neoplasms; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatofibrosarcoma; Melanoma; Histiocytoma, Malignant Fibrous; Neoplasms, Adnexal and Skin Appendage

 

Last Updated: 10 Aug 2015

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To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
 

Status: Recruiting

Condition Summary: Neuroblastoma;; Rhabdomyosarcoma;; Ewing's Sarcoma;; Ewing's Tumor;; Sarcoma, Ewing's;; Sarcomas, Epitheliod;; Sarcoma, Soft Tissue;; Sarcoma, Spindle Cell;; Melanoma;; Malignant Melanoma;; Clinical Oncology;; Oncology, Medical;; Pediatrics, Osteosarcoma;; Osteogenic Sarcoma;; Osteosarcoma Tumor;; Sarcoma, Osteogenic;; Tumors;; Cancer;; Neoplasia;; Neoplasm;; Histiocytoma;; Fibrosarcoma;; Dermatofibrosarcoma

 

Last Updated: 25 Nov 2015

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