Dermatofibroma

Common Name(s)

Dermatofibroma

A dermatofibroma is a round, brown or reddish purple growth that can be found anywhere on the body, but most commonly appears on the legs or other frequently exposed areas. They often feel hard under the skin.

The causes for dermatofibromas may vary, but they are often a result of minor injuries such as bug bites or splinters. They are known to be benign, not harmful or cancerous, but a biopsy may be used to confirm this. Because they are not life threatening and not harmful, they are often best left alone. Surgery may remove the dermatofibroma, but the scar is often worse than the lump because it is often very deeply rooted in the skin. If it interferes with shaving or is frequently irritated by clothing, it may be shaved down, frozen, or "punched" to deflate it. However, this process is not permanent and the dermatofibroma may reappear. If you have been diagnosed with a dermatofibroma, talk to a doctor or dermatologist to discuss the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatofibroma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dermatofibroma" returned 23 free, full-text research articles on human participants. First 3 results:

Myxoid dermatofibroma on a great toe: a case report.
 

Author(s): Ahrim Moon, Nara Yoon, Hyun-Soo Kim

Journal:

 

Dermatofibroma is a common benign fibrohistiocytic tumor with many clinicopathological variants. Myxoid dermatofibroma is one of these variants, which is characterized by marked stromal mucin deposition. This report presents a case of myxoid dermatofibroma on a great toe that had ...

Last Updated: 11 Aug 2015

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Clinical and histological patterns of dermatofibroma without gross skin surface change: A comparative study with conventional dermatofibroma.
 

Author(s): Woo Jin Lee, Joon Min Jung, Chong Hyun Won, Sung Eun Chang, Jee Ho Choi, Kee Chan Moon, Mi Woo Lee

Journal: Indian J Dermatol Venereol Leprol. ;81(3):263-9.

 

Dermatofibroma sometimes clinically presents as a nodular lesion without gross skin surface change. Clinicopathologic features of this variant of dermatofibroma have not been evaluated.

Last Updated: 7 May 2015

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Aneurysmal dermatofibroma mimicking both clinical and dermoscopic malignant melanoma and Kaposi's sarcoma.
 

Author(s): Silviu Horia Morariu, Mircea Suciu, Mihai Dorin Vartolomei, Mihail Alexandru Badea, Ovidiu Simion Cotoi

Journal: Rom J Morphol Embryol. 2014 ;55(3 Suppl):1221-4.

 

Aneurysmal dermatofibroma (AD) or aneurysmal fibrous histiocytoma (AFH) is a relatively rare form of histiocytoma representing less than 2% of total cases. It shares many clinical and dermoscopic similarities with skin tumors, especially malignant melanoma and Kaposi's sarcoma, which ...

Last Updated: 22 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dermatofibroma" returned 2 free, full-text review articles on human participants. First 3 results:

[Dermatofibroma metastasizing to the lung: current treatment].
 

Author(s): Enrique Bermejo Casero, David Pérez Alonso, Santiago Quevedo Losada, Luis López Rivero

Journal: Arch. Bronconeumol.. 2009 Oct;45(10):521-3.

 

Dermatofibromas are very common skin tumors. Their typical presentation is as a slow-growing, firm, solitary papule. They have been described histopathologically as a reaction of the connective tissue of the skin or as a benign neoplasm. Cases of these tumors metastasizing to the ...

Last Updated: 28 Sep 2009

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Role of mast cells in dermatofibroma: recent viewpoints into the pathogenesis.
 

Author(s): Toshiyuki Yamamoto, Ichiro Katayama, Kiyoshi Nishioka

Journal: Eur J Dermatol. ;13(5):419-23.

 

Mast cells are often discussed to play an important role in the tissue fibrotic process, because increased numbers of mast cells are found in the fibrous lesions. Recent evidence has revealed that mast cells are a rich source of cytokines or mediators, which are supposed to play a ...

Last Updated: 24 Dec 2003

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Adult Fibrosarcoma; Alveolar Soft Part Sarcoma; Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Clear Cell Sarcoma of Soft Tissue; Epithelioid Malignant Peripheral Nerve Sheath Tumor; Epithelioid Sarcoma; Extraskeletal Myxoid Chondrosarcoma; Extraskeletal Osteosarcoma; Fibrohistiocytic Neoplasm; Glomus Tumor of the Skin; Inflammatory Myofibroblastic Tumor; Intimal Sarcoma; Leiomyosarcoma; Liposarcoma; Low Grade Fibromyxoid Sarcoma; Low Grade Myofibroblastic Sarcoma; Malignant Cutaneous Granular Cell Tumor; Malignant Peripheral Nerve Sheath Tumor; Malignant Triton Tumor; Mesenchymal Chondrosarcoma; Myxofibrosarcoma; Myxoid Chondrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Nerve Sheath Neoplasm; PEComa; Pericytic Neoplasm; Plexiform Fibrohistiocytic Tumor; Sclerosing Epithelioid Fibrosarcoma; Stage IB Soft Tissue Sarcoma; Stage IIB Soft Tissue Sarcoma; Stage III Soft Tissue Sarcoma; Stage IV Soft Tissue Sarcoma; Synovial Sarcoma; Undifferentiated (Embryonal) Sarcoma; Undifferentiated High Grade Pleomorphic Sarcoma of Bone

 

Last Updated: 29 Nov 2016

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Spanish Registry of Mohs Surgery
 

Status: Recruiting

Condition Summary: Skin Neoplasms; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatofibrosarcoma; Melanoma; Histiocytoma, Malignant Fibrous; Neoplasms, Adnexal and Skin Appendage

 

Last Updated: 11 Sep 2016

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To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
 

Status: Recruiting

Condition Summary: Neuroblastoma;; Rhabdomyosarcoma;; Ewing's Sarcoma;; Ewing's Tumor;; Sarcoma, Ewing's;; Sarcomas, Epitheliod;; Sarcoma, Soft Tissue;; Sarcoma, Spindle Cell;; Melanoma;; Malignant Melanoma;; Clinical Oncology;; Oncology, Medical;; Pediatrics, Osteosarcoma;; Osteogenic Sarcoma;; Osteosarcoma Tumor;; Sarcoma, Osteogenic;; Tumors;; Cancer;; Neoplasia;; Neoplasm;; Histiocytoma;; Fibrosarcoma;; Dermatofibrosarcoma

 

Last Updated: 22 Aug 2016

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