Depersonalization Disorder

Common Name(s)

Depersonalization Disorder

Depersonalization disorder is a mental health condition in which a person feels disconnected from their body. People with this condition feel as if they are observing their life from outside their body and that things around them are not real. For some, the symptoms are mild and last just a short time. When symptoms are chronic, or last over a longer period of time, they can become very problematic and interfere with daily life. Depersonalization disorder rarely occurs alone and is usually a symptom of another disorder. Dangerous situations commonly trigger periods of depersonalization. A psychiatrist or psychologist can diagnose depersonalization disorder through interviews and assessment tools. In order to be diagnosed the patient must have periods of depersonalization, in which they realize the experience is not real, symptoms interfere with their life, and symptoms are not caused by the effects of another mental health disorder, alcohol or drugs. Treatment for depersonalization disorder is primarily talk therapy, however medication may be added if needed.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Depersonalization Disorder" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Depersonalization Disorder" returned 8 free, full-text research articles on human participants. First 3 results:

Grey matter alterations in patients with depersonalization disorder: a voxel-based morphometry study.
 

Author(s): Judith K Daniels, Michael Gaebler, Jan-Peter Lamke, Henrik Walter

Journal: J Psychiatry Neurosci. 2015 Jan;40(1):19-27.

 

To our knowledge, no whole brain investigation of morphological aberrations in dissociative disorder is available to date. Previous region-of-interest studies focused exclusively on amygdalar, hippocampal and parahippocampal grey matter volumes and did not include patients with depersonalization ...

Last Updated: 18 Dec 2014

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Striking discrepancy of anomalous body experiences with normal interoceptive accuracy in depersonalization-derealization disorder.
 

Author(s): Matthias Michal, Bettina Reuchlein, Julia Adler, Iris Reiner, Manfred E Beutel, Claus Vögele, Hartmut Schächinger, André Schulz

Journal:

 

Disembodiment is a core feature of depersonalization disorder (DPD). Given the narratives of DPD patients about their disembodiment and emotional numbing and neurobiological findings of an inhibition of insular activity, DPD may be considered as a mental disorder with specific impairments ...

Last Updated: 3 Mar 2014

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Testing a neurobiological model of depersonalization disorder using repetitive transcranial magnetic stimulation.
 

Author(s): Emma-Louise Jay, Mauricio Sierra, Frederique Van den Eynde, John C Rothwell, Anthony S David

Journal: Brain Stimul. ;7(2):252-9.

 

Depersonalization disorder (DPD) includes changes in subjective experiencing of self, encompassing emotional numbing. Functional magnetic resonance imaging (fMRI) has pointed to ventrolateral prefrontal cortex (VLPFC) inhibition of insula as a neurocognitive correlate of the disorder.

Last Updated: 17 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Depersonalization Disorder" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Depersonalization Disorder With Repetitive Transcranial Magnetic Stimulation (rTMS)
 

Status: Recruiting

Condition Summary: Depersonalization Disorder

 

Last Updated: 30 Sep 2014

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Depersonalization Disorder: Therapeutic Effect of Neuronavigated Repetitive Transcranial Stimulation
 

Status: Recruiting

Condition Summary: Depersonalization Disorder

 

Last Updated: 23 Jun 2015

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Feasibility Trial of CBT for Depersonalisation in Psychosis
 

Status: Recruiting

Condition Summary: Psychotic Disorders; Depersonalization

 

Last Updated: 27 Apr 2015

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