Dengue

Common Name(s)

Dengue, Dengue virus, susceptibility to

Dengue is a virus that is carried by mosquitos and affects over 100 million people worldwide each year. The virus is passed to humans through mosquito bites. Those who inhabit or visit tropical or sub-tropical regions, particularly in urban or suburban areas, are most at risk for infection. Symptoms of Dengue include a high fever, intense headache or aching behind the eyes, joint pain, easy bruising, gum or nose bleeds, bone and muscle pain, swollen glands, and a rash. Symptoms usually appear 4-10 days after infection and last for 2-7 days.

There are four types of dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. Once an individual has recovered from one of these types, that individual will not develop symptoms from that same type again. When an individual is infected by a different type, however, there is a risk for severe dengue. Symptoms of severe dengue include vomiting (sometimes bloody), tiredness, severe stomach pain, fast breathing, restlessness, and bleeding gums. These symptoms occur after the high fever of dengue has dropped. Severe dengue requires immediate treatment, as it can cause the liquid part of the blood (plasma) to leak from small blood vessels (capillaries). This condition leads to severe loss of blood volume (shock) and can be life-threatening. Other complications may include internal bleeding, difficulty breathing, and accumulation of fluid in the body.

Severe dengue is treated by fluid replacement therapy. Dengue prevention methods focus on avoiding mosquitos, such as by getting rid of stagnant water in containers where mosquitos lay eggs and using bed nets during the night and mosquito repellant when outdoors. If you have been diagnosed with dengue, talk to your doctor about current treatment options. In addition, consult a medical professional for advice before traveling to areas where there is a potential to be infected by the dengue virus.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dengue" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dengue" returned 3511 free, full-text research articles on human participants. First 3 results:

"Preliminary Seroepidemiological survey of dengue infections in Pakistan, 2009-2014".
 

Author(s): Muhammad Suleman, Hyeong-Woo Lee, Syed Sohail Zahoor Zaidi, Muhammad Masroor Alam, Nadia Nisar, Uzma Bashir Aamir, Salmaan Sharif, Shahzad Shaukat, Adnan Khurshid, Mehar Angez, Massab Umair, Ghulam Mujtaba, Rani Faryal

Journal:

 

Dengue virus is the causative agent of dengue fever, a vector borne infection which causes self-limiting to life threatening disease in humans. A sero-epidemiological study was conducted to understand the current epidemiology of dengue virus in Pakistan which is now known as a dengue ...

Last Updated: 9 Mar 2017

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Differentiating between dengue fever and malaria using hematological parameters in endemic areas of Thailand.
 

Author(s): Manas Kotepui, Bhukdee PhunPhuech, Nuoil Phiwklam, Kwuntida Uthaisar

Journal:

 

Dengue fever (DF) and malaria are the two major public health concerns in tropical countries such as Thailand. Early differentiation between dengue and malaria could help clinicians to identify patients who should be closely monitored for signs of dengue hemorrhagic fever or severe ...

Last Updated: 2 Mar 2017

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Association of interleukin-2, -4 and -10 with dengue severity.
 

Author(s): Kumar S Abhishek, Anita Chakravarti, C P Baveja, Naresh Kumar, Oves Siddiqui, Suman Kumar

Journal: Indian J Pathol Microbiol. ;60(1):66-69.

 

Dengue is an arboviral disease caused by four distinct serotypes of dengue virus. The pathogenesis of dengue is not very clearly understood. Various pro- and anti-inflammatory cytokines are involved in the immune pathogenesis of dengue. Interleukin (IL)-2/IL-2 receptor interaction ...

Last Updated: 14 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dengue" returned 256 free, full-text review articles on human participants. First 3 results:

Dengue-associated hemophagocytic lymphohistiocytosis in an adult: A case report and literature review.
 

Author(s): Sang Mi Chung, Joon Young Song, Wonshik Kim, Min Joo Choi, Ji Ho Jeon, Seonghui Kang, Eunju Jung, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim

Journal: Medicine (Baltimore). 2017 02;96(8):e6159.

 

Infection-associated hemophagocytic syndrome (IAHS) is potentially a fatal disease caused by systemic infection complicated by hemophagocyticlymphohistiocytosis (HLH). Here, we report a case of HLH associated with dengue hemorrhagic fever (DHF) after a trip to Thailand.

Last Updated: 22 Feb 2017

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Dengue Fever: Causes, Complications, and Vaccine Strategies.
 

Author(s): Niyati Khetarpal, Ira Khanna

Journal: J Immunol Res. 2016 ;2016():6803098.

 

Dengue is a highly endemic infectious disease of the tropical countries and is rapidly becoming a global burden. It is caused by any of the 4 serotypes of dengue virus and is transmitted within humans through female Aedes mosquitoes. Dengue disease varies from mild fever to severe ...

Last Updated: 15 Aug 2016

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Vaccines and immunization strategies for dengue prevention.
 

Author(s): Yang Liu, Jianying Liu, Gong Cheng

Journal:

 

Dengue is currently the most significant arboviral disease afflicting tropical and sub-tropical countries worldwide. Dengue vaccines, such as the multivalent attenuated, chimeric, DNA and inactivated vaccines, have been developed to prevent dengue infection in humans, and they function ...

Last Updated: 20 Jul 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 20 Jan 2017

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TDENV PIV and LAV Dengue Prime-boost Strategy
 

Status: Recruiting

Condition Summary: Dengue

 

Last Updated: 18 Aug 2016

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