Dengue

Common Name(s)

Dengue, Dengue virus, susceptibility to

Dengue is a virus that is carried by mosquitos and affects over 100 million people worldwide each year. The virus is passed to humans through mosquito bites. Those who inhabit or visit tropical or sub-tropical regions, particularly in urban or suburban areas, are most at risk for infection. Symptoms of Dengue include a high fever, intense headache or aching behind the eyes, joint pain, easy bruising, gum or nose bleeds, bone and muscle pain, swollen glands, and a rash. Symptoms usually appear 4-10 days after infection and last for 2-7 days.

There are four types of dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. Once an individual has recovered from one of these types, that individual will not develop symptoms from that same type again. When an individual is infected by a different type, however, there is a risk for severe dengue. Symptoms of severe dengue include vomiting (sometimes bloody), tiredness, severe stomach pain, fast breathing, restlessness, and bleeding gums. These symptoms occur after the high fever of dengue has dropped. Severe dengue requires immediate treatment, as it can cause the liquid part of the blood (plasma) to leak from small blood vessels (capillaries). This condition leads to severe loss of blood volume (shock) and can be life-threatening. Other complications may include internal bleeding, difficulty breathing, and accumulation of fluid in the body.

Severe dengue is treated by fluid replacement therapy. Dengue prevention methods focus on avoiding mosquitos, such as by getting rid of stagnant water in containers where mosquitos lay eggs and using bed nets during the night and mosquito repellant when outdoors. If you have been diagnosed with dengue, talk to your doctor about current treatment options. In addition, consult a medical professional for advice before traveling to areas where there is a potential to be infected by the dengue virus.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dengue" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dengue" returned 3380 free, full-text research articles on human participants. First 3 results:

Socioeconomic and environmental determinants of dengue transmission in an urban setting: An ecological study in Nouméa, New Caledonia.
 

Author(s): Raphaël M Zellweger, Jorge Cano, Morgan Mangeas, François Taglioni, Alizé Mercier, Marc Despinoy, Christophe E Menkès, Myrielle Dupont-Rouzeyrol, Birgit Nikolay, Magali Teurlai

Journal:

 

Dengue is a mosquito-borne virus that causes extensive morbidity and economic loss in many tropical and subtropical regions of the world. Often present in cities, dengue virus is rapidly spreading due to urbanization, climate change and increased human movements. Dengue cases are ...

Last Updated: 3 Apr 2017

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Mathematical Modelling of Immune Parameters in the Evolution of Severe Dengue.
 

Author(s): M K Premaratne, S S N Perera, G N Malavige, Saroj Jayasinghe

Journal: Comput Math Methods Med. 2017 ;2017():2187390.

 

Aims. Predicting the risk of severity at an early stage in an individual patient will be invaluable in preventing morbidity and mortality caused by dengue. We hypothesized that such predictions are possible by analyzing multiple parameters using mathematical modeling. Methodology. ...

Last Updated: 15 Mar 2017

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"Preliminary Seroepidemiological survey of dengue infections in Pakistan, 2009-2014".
 

Author(s): Muhammad Suleman, Hyeong-Woo Lee, Syed Sohail Zahoor Zaidi, Muhammad Masroor Alam, Nadia Nisar, Uzma Bashir Aamir, Salmaan Sharif, Shahzad Shaukat, Adnan Khurshid, Mehar Angez, Massab Umair, Ghulam Mujtaba, Rani Faryal

Journal:

 

Dengue virus is the causative agent of dengue fever, a vector borne infection which causes self-limiting to life threatening disease in humans. A sero-epidemiological study was conducted to understand the current epidemiology of dengue virus in Pakistan which is now known as a dengue ...

Last Updated: 9 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dengue" returned 265 free, full-text review articles on human participants. First 3 results:

Current Status of Dengue Therapeutics Research and Development.
 

Author(s): Jenny G H Low, Eng Eong Ooi, Subhash G Vasudevan

Journal: J. Infect. Dis.. 2017 Mar;215(suppl_2):S96-S102.

 

Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed ...

Last Updated: 13 Apr 2017

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Dengue-associated hemophagocytic lymphohistiocytosis in an adult: A case report and literature review.
 

Author(s): Sang Mi Chung, Joon Young Song, Wonshik Kim, Min Joo Choi, Ji Ho Jeon, Seonghui Kang, Eunju Jung, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim

Journal: Medicine (Baltimore). 2017 02;96(8):e6159.

 

Infection-associated hemophagocytic syndrome (IAHS) is potentially a fatal disease caused by systemic infection complicated by hemophagocyticlymphohistiocytosis (HLH). Here, we report a case of HLH associated with dengue hemorrhagic fever (DHF) after a trip to Thailand.

Last Updated: 22 Feb 2017

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The epidemiology of dengue infection: Harnessing past experience and current knowledge to support implementation of future control strategies.
 

Author(s): Narayan Gyawali, Richard S Bradbury, Andrew W Taylor-Robinson

Journal: J Vector Borne Dis. ;53(4):293-304.

 

Dengue is the most important mosquito-borne viral infection of humans. Although outbreaks of disease which are now recognized as clinically consistent with dengue have been reported for centuries, it was not until half a century ago that laboratory identification of dengue viruses ...

Last Updated: 30 Dec 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 5 Apr 2017

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TDENV PIV and LAV Dengue Prime-boost Strategy
 

Status: Recruiting

Condition Summary: Dengue

 

Last Updated: 18 Aug 2016

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