Dementia

Common Name(s)

Dementia

Dementia is not a disease, but is a term that describes a loss of cognitive functioning, such as thinking, remembering, and reasoning, and behavioral abilities to the extent that it interferes with a person’s daily life. Many conditions cause dementia and symptoms may vary depending on the cause. However, common symptoms include memory loss, difficulty communicating, difficulty planning and organizing, difficulty with motor functions, personality changes, disorientation, paranoia, inability to reason and inappropriate behavior. A physician can diagnose dementias after taking into account medical history and performance on a number of tests such as cognitive and neuropsychological tests, brain scans, blood tests, and psychiatric evaluation. Most types of dementia cannot be cured, however medication and occupational therapy can be used to manage symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia" for support, advocacy or research.

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Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

Last Updated: 8 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia" for support, advocacy or research.

Logo
Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

http://www.nia.nih.gov/alzheimers

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

http://www.theaftd.org

Last Updated: 8 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dementia" returned 5070 free, full-text research articles on human participants. First 3 results:

Contribution of cognitive performance and cognitive decline to associations between socioeconomic factors and dementia: A cohort study.
 

Author(s): Jennifer Rusmaully, Aline Dugravot, Jean-Paul Moatti, Michael G Marmot, Alexis Elbaz, Mika Kivimaki, Séverine Sabia, Archana Singh-Manoux

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Socioeconomic disadvantage is a risk factor for dementia, but longitudinal studies suggest that it does not affect the rate of cognitive decline. Our objective is to understand the manner in which socioeconomic disadvantage shapes dementia risk by examining its associations with midlife ...

Last Updated: 26 Jun 2017

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Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study.
 

Author(s): Séverine Sabia, Aline Dugravot, Jean-François Dartigues, Jessica Abell, Alexis Elbaz, Mika Kivimäki, Archana Singh-Manoux

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Objective To test the hypotheses that physical activity in midlife is not associated with a reduced risk of dementia and that the preclinical phase of dementia is characterised by a decline in physical activity.Design Prospective cohort study with a mean follow-up of 27 years.Setting Civil ...

Last Updated: 23 Jun 2017

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Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study.
 

Author(s): Enrico Premi, Mario Grassi, John van Swieten, Daniela Galimberti, Caroline Graff, Mario Masellis, Carmela Tartaglia, Fabrizio Tagliavini, James B Rowe, Robert Laforce, Elizabeth Finger, Giovanni B Frisoni, Alexandre de Mendonça, Sandro Sorbi, Stefano Gazzina, Maura Cosseddu, Silvana Archetti, Roberto Gasparotti, Marta Manes, Antonella Alberici, Manuel J Cardoso, Martina Bocchetta, David M Cash, Sebastian Ourselin, Alessandro Padovani, Jonathan D Rohrer, Barbara Borroni,

Journal: Brain. 2017 Jun;140(6):1784-1791.

 

Frontotemporal dementia is a heterogeneous neurodegenerative disorder with around a third of cases having autosomal dominant inheritance. There is wide variability in phenotype even within affected families, raising questions about the determinants of the progression of disease and ...

Last Updated: 1 May 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dementia" returned 825 free, full-text review articles on human participants. First 3 results:

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.
 

Author(s): Ian G McKeith, Bradley F Boeve, Dennis W Dickson, Glenda Halliday, John-Paul Taylor, Daniel Weintraub, Dag Aarsland, James Galvin, Johannes Attems, Clive G Ballard, Ashley Bayston, Thomas G Beach, Frédéric Blanc, Nicolaas Bohnen, Laura Bonanni, Jose Bras, Patrik Brundin, David Burn, Alice Chen-Plotkin, John E Duda, Omar El-Agnaf, Howard Feldman, Tanis J Ferman, Dominic Ffytche, Hiroshige Fujishiro, Douglas Galasko, Jennifer G Goldman, Stephen N Gomperts, Neill R Graff-Radford, Lawrence S Honig, Alex Iranzo, Kejal Kantarci, Daniel Kaufer, Walter Kukull, Virginia M Y Lee, James B Leverenz, Simon Lewis, Carol Lippa, Angela Lunde, Mario Masellis, Eliezer Masliah, Pamela McLean, Brit Mollenhauer, Thomas J Montine, Emilio Moreno, Etsuro Mori, Melissa Murray, John T O'Brien, Sotoshi Orimo, Ronald B Postuma, Shankar Ramaswamy, Owen A Ross, David P Salmon, Andrew Singleton, Angela Taylor, Alan Thomas, Pietro Tiraboschi, Jon B Toledo, John Q Trojanowski, Debby Tsuang, Zuzana Walker, Masahito Yamada, Kenji Kosaka

Journal: Neurology. 2017 Jul;89(1):88-100.

 

The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The revised DLB consensus criteria now distinguish clearly between ...

Last Updated: 8 Jun 2017

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Frontotemporal dementia as a comorbidity to idiopathic normal pressure hydrocephalus (iNPH): a short review of literature and an unusual case.
 

Author(s): V E Korhonen, E Solje, N M Suhonen, T Rauramaa, R Vanninen, A M Remes, V Leinonen

Journal:

 

Behavioural variant frontotemporal dementia (bvFTD) and idiopathic normal pressure hydrocephalus (iNPH) are neurodegenerative diseases that can present with similar symptoms. These include decline in executive functions, psychomotor slowness, and behavioural and personality changes. ...

Last Updated: 19 Apr 2017

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Genetics of vascular dementia - review from the ICVD working group.
 

Author(s): M Arfan Ikram, Anna Bersano, Raquel Manso-Calderón, Jian-Ping Jia, Helena Schmidt, Lefkos Middleton, Benedetta Nacmias, Saima Siddiqi, Hieab H H Adams

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Vascular dementia is a common disorder resulting in considerable morbidity and mortality. Determining the extent to which genes play a role in disease susceptibility and their pathophysiological mechanisms could improve our understanding of vascular dementia, leading to a potential ...

Last Updated: 6 Mar 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hand Grasping Techniques on Eliciting the Grasp Reflex in Patients With Dementia
 

Status: Recruiting

Condition Summary: Dementia

 

Last Updated: 4 Oct 2016

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A Trial of the C-TraC Intervention for Dementia Patients
 

Status: Recruiting

Condition Summary: Dementia

 

Last Updated: 2 May 2017

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Last Updated: 18 Aug 2015

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