Dementias

Common Name(s)

Dementias

Dementia is not a disease, but is a term that describes a loss of cognitive functioning, such as thinking, remembering, and reasoning, and behavioral abilities to the extent that it interferes with a person’s daily life. Many conditions cause dementia and symptoms may vary depending on the cause. However, common symptoms include memory loss, difficulty communicating, difficulty planning and organizing, difficulty with motor functions, personality changes, disorientation, paranoia, inability to reason and inappropriate behavior. A physician can diagnose dementias after taking into account medical history and performance on a number of tests such as cognitive and neuropsychological tests, brain scans, blood tests, and psychiatric evaluation. Most types of dementia cannot be cured, however medication and occupational therapy can be used to manage symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementias" for support, advocacy or research.

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Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

Last Updated: 10 Dec 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementias" for support, advocacy or research.

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Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

http://www.nia.nih.gov/alzheimers

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

http://www.theaftd.org

Last Updated: 10 Dec 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dementias" returned 69 free, full-text research articles on human participants. First 3 results:

Morphometry of the hippocampal microvasculature in post-stroke and age-related dementias.
 

Author(s): M J C Burke, L Nelson, J Y Slade, A E Oakley, A A Khundakar, R N Kalaria

Journal: Neuropathol. Appl. Neurobiol.. 2014 Apr;40(3):284-95.

 

Optimal vascular function is vital for prevention of dementia. We hypothesized that elderly post-stroke survivors who preserve cognitive function show unperturbed cerebral microvasculature compared with those who develop dementia.

Last Updated: 17 Mar 2014

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The orbitofrontal cortex is involved in emotional enhancement of memory: evidence from the dementias.
 

Author(s): Fiona Kumfor, Muireann Irish, John R Hodges, Olivier Piguet

Journal: Brain. 2013 Oct;136(Pt 10):2992-3003.

 

The enhancing effect of emotion on subsequent memory retrieval is well established. Patients with frontotemporal dementia show profound emotion processing difficulties, yet the extent to which such deficits attenuate emotional enhancement of memory remains unknown. Here, we studied ...

Last Updated: 27 Sep 2013

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Occupational differences between Alzheimer's and aphasic dementias: implication for teachers.
 

Author(s): Keith A Josephs, Sarah M Papenfuss, Joseph R Duffy, Edythe A Strand, Mary M Machulda, Jennifer L Whitwell, Ronald C Petersen

Journal: Am J Alzheimers Dis Other Demen. 2013 Sep;28(6):612-6.

 

We aimed to determine whether there is an association between teaching and the development of progressive speech and language disorders (SLDs). Occupation was compared between 100 patients with a progressive SLD, 404 patients with Alzheimer's dementia, and the 2008 US census. In SLDs, ...

Last Updated: 28 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dementias" returned 35 free, full-text review articles on human participants. First 3 results:

Magnetic resonance spectroscopy in common dementias.
 

Author(s): Kejal Kantarci

Journal: Neuroimaging Clin. N. Am.. 2013 Aug;23(3):393-406.

 

Neurodegenerative dementias are characterized by elevated myoinositol and decreased N-acetylaspartate (NAA) levels. The increase in myoinositol seems to precede decreasing NAA levels in Alzheimer's diseases. NAA/myo-inositol ratio in the posterior cingulate gyri decreases with increasing ...

Last Updated: 9 Aug 2013

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Comparison of informal care time and costs in different age-related dementias: a review.
 

Author(s): Nadège Costa, Laura Ferlicoq, Hélène Derumeaux-Burel, Thomas Rapp, Valérie Garnault, Sophie Gillette-Guyonnet, Sandrine Andrieu, Bruno Vellas, Michel Lamure, Alain Grand, Laurent Molinier

Journal: Biomed Res Int. 2013 ;2013():852368.

 

Age-related dementia is a progressive degenerative brain syndrome whose prevalence increases with age. Dementias cause a substantial burden on society and on families who provide informal care. This study aims to review the relevant papers to compare informal care time and costs in ...

Last Updated: 19 Mar 2013

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Vascular disease and dementias: paradigm shifts to drive research in new directions.
 

Author(s): Mitchel A Kling, John Q Trojanowski, David A Wolk, Virginia M Y Lee, Steven E Arnold

Journal: Alzheimers Dement. 2013 Jan;9(1):76-92.

 

Vascular disease was once considered the principal cause of aging-related dementia. More recently, however, research emphasis has shifted to studies of progressive neurodegenerative disease processes, such as those giving rise to neuritic plaques, neurofibrillary tangles, and Lewy ...

Last Updated: 11 Jan 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluating the Effects of Music Interventions on Hospitalised People With Dementia
 

Status: Not yet recruiting

Condition Summary: Dementia; Alzheimer's Disease; Dementia, Vascular; Lewy Body Disease

 

Last Updated: 14 Mar 2007

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Young Onset Dementia - the Difficult Diagnosis and the Stressful Life for the Whole Family
 

Status: Recruiting

Condition Summary: Frontotemporal Dementia; Alzheimer's Disease.

 

Last Updated: 2 Apr 2014

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Behavioral Interventions to Prevent or Delay Dementia
 

Status: Recruiting

Condition Summary: Mild Cognitive Impairment; Memory Disorders; Mild Dementia; Impaired Cognition; Mild Cognitive Disorder; Amnestic Disorder; Dementia and Amnestic Conditions; Poor Short-term Memory; Memory Impairment

 

Last Updated: 3 Nov 2014

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