Dementia

Common Name(s)

Dementia

Dementia is not a disease, but is a term that describes a loss of cognitive functioning, such as thinking, remembering, and reasoning, and behavioral abilities to the extent that it interferes with a person’s daily life. Many conditions cause dementia and symptoms may vary depending on the cause. However, common symptoms include memory loss, difficulty communicating, difficulty planning and organizing, difficulty with motor functions, personality changes, disorientation, paranoia, inability to reason and inappropriate behavior. A physician can diagnose dementias after taking into account medical history and performance on a number of tests such as cognitive and neuropsychological tests, brain scans, blood tests, and psychiatric evaluation. Most types of dementia cannot be cured, however medication and occupational therapy can be used to manage symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia" for support, advocacy or research.

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Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

Last Updated: 8 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia" for support, advocacy or research.

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Alzheimer's Disease Education and Referral Center

The Alzheimer's Disease Education and Referral Center was established by the National Institute on Aging (NIA) to provide information to health professionals, patients and their families and the public about Alzheimer's disease and other memory disorders.

http://www.nia.nih.gov/alzheimers

Last Updated: 30 Oct 2014

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Association for Frontotemporal Degeneration

The Association for Frontotemporal Degeneration (AFTD) is a nationwide non-profit organization whose mission is to promote and fund research into finding the cause and cure for the frontotemporal dementias; to provide information, education, and support to persons diagnosed with frontotemporal dementias (FTD) and their families and caregivers; and to educate physicians and allied health professionals about FTD.

http://www.theaftd.org

Last Updated: 8 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dementia" returned 4455 free, full-text research articles on human participants. First 3 results:

Reasons for acute psychiatric admission of patients with dementia.
 

Author(s): Rozalia Takacs, Gabor S Ungvari, Gabor Gazdag

Journal: Neuropsychopharmacol Hung. 2015 Sep;17(3):141-5.

 

The estimated number of patients living with dementia in Hungary is between 150,000 and 300,000. Hungary's prevalence of vascular dementia is much higher than that of other countries. Patients with dementia can be admitted to psychiatric hospitals for several reasons, the least common ...

Last Updated: 21 Oct 2015

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Pain and temperature processing in dementia: a clinical and neuroanatomical analysis.
 

Author(s): Phillip D Fletcher, Laura E Downey, Hannah L Golden, Camilla N Clark, Catherine F Slattery, Ross W Paterson, Jonathan D Rohrer, Jonathan M Schott, Martin N Rossor, Jason D Warren

Journal: Brain. 2015 Nov;138(Pt 11):3360-72.

 

Symptoms suggesting altered processing of pain and temperature have been described in dementia diseases and may contribute importantly to clinical phenotypes, particularly in the frontotemporal lobar degeneration spectrum, but the basis for these symptoms has not been characterized ...

Last Updated: 27 Oct 2015

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Effect of Sancaijiangtang on plasma nitric oxide and endothelin-1 levels in patients with type 2 diabetes mellitus and vascular dementia: a single-blind randomized controlled trial.
 

Author(s): Guo Qiang, Cao Wenzhai, Zhao Huan, Zhu Yuxia, Yang Dongdong, Zhong Sen, Chen Qiu

Journal: J Tradit Chin Med. 2015 Aug;35(4):375-80.

 

To observe the effect of Sancaijiangtang powders on plasma nitric oxide and endothelin-1 levels. We sought to identify the common pathological link and mechanism of action for Traditional Chinese medicine in type 2 diabetes mellitus and vascular dementia, and to explicate the material ...

Last Updated: 2 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dementia" returned 664 free, full-text review articles on human participants. First 3 results:

CLINICAL PRACTICE. Advanced Dementia.
 

Author(s): Susan L Mitchell

Journal: N. Engl. J. Med.. 2015 Jun;372(26):2533-40.

 

Last Updated: 25 Jun 2015

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Cerebrospinal Fluid Biomarkers in Familial Forms of Alzheimer's Disease and Frontotemporal Dementia.
 

Author(s): Nina Rostgaard, Gunhild Waldemar, Jørgen Erik Nielsen, Anja Hviid Simonsen

Journal: Dement Geriatr Cogn Disord. 2015 ;40(1-2):54-62.

 

As dementia is a fast-growing health care problem, it is becoming an increasingly urgent need to provide an early diagnosis in order to offer patients the best medical treatment and care. Validated biomarkers which reflect the pathology and disease progression are essential for diagnosis ...

Last Updated: 3 Jul 2015

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Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease.
 

Author(s): Melanie D Sweeney, Abhay P Sagare, Berislav V Zlokovic

Journal: J. Cereb. Blood Flow Metab.. 2015 Jul;35(7):1055-68.

 

Alzheimer's disease (AD) is the most common form of age-related dementias. In addition to genetics, environment, and lifestyle, growing evidence supports vascular contributions to dementias including dementia because of AD. Alzheimer's disease affects multiple cell types within the ...

Last Updated: 30 Jun 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Optimizing Dementia Care Through Collaborative Recovery Interventions
 

Status: Not yet recruiting

Condition Summary: Alzheimer's Disease; Dementia; Dementia, Vascular; Caregivers; Veterans

 

Last Updated: 6 Nov 2015

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Evaluating the Effects of Music Interventions on Hospitalised People With Dementia
 

Status: Not yet recruiting

Condition Summary: Dementia; Alzheimer's Disease; Dementia, Vascular; Lewy Body Disease

 

Last Updated: 14 Mar 2007

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Study of Social Behavior and Emotion in Frontotemporal Dementia, Alzheimer's Disease and Controls
 

Status: Recruiting

Condition Summary: Frontotemporal Dementia; Frontotemporal Degeneration; Alzheimer's Disease; Social Behavior

 

Last Updated: 27 Oct 2011

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