Addison's Disease

Common Name(s)

Addison's Disease

Addison's disease is a condition that occurs when the adrenal glands do not produce enough of their hormones. This condition can be caused by damage to the adrenal glands, autoimmune conditions, and certain genetic conditions. Some of the symptoms include changes in blood pressure, chronic diarrhea, darkening of the skin, paleness, extreme weakness, fatigue, nausea and vomiting, salt craving, and weight loss. Treatment with replacement corticosteroids usually controls the symptoms.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Addison's Disease" for support, advocacy or research.

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National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

Last Updated: 13 Oct 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Addison's Disease" for support, advocacy or research.

Logo
National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

http://www.nadf.us

Last Updated: 13 Oct 2014

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Addison's Disease" returned 183 free, full-text research articles on human participants. First 3 results:

Altered DNA methylation profile in Norwegian patients with Autoimmune Addison's Disease.
 

Author(s): Trine E Bjanesoy, Bettina Kulle Andreassen, Eirik Bratland, Andrew Reiner, Shahinul Islam, Eystein S Husebye, Marit Bakke

Journal: Mol. Immunol.. 2014 Jun;59(2):208-16.

 

Autoimmune Addison's Disease (AAD) is an endocrine and immunological disease of uncertain pathogenesis resulting from the immune system's destruction of the hormone producing cells of the adrenal cortex. The underlying molecular mechanisms are largely unknown, but it is commonly accepted ...

Last Updated: 7 Apr 2014

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9β Polymorphism of the glucocorticoid receptor gene appears to have limited impact in patients with Addison's disease.
 

Author(s): Ian Louis Ross, Collet Dandara, Marelize Swart, Miguel Lacerda, Desmond Schatz, Dirk Jacobus Blom

Journal:

 

Addison's disease (AD) has been associated with an increased risk of cardiovascular disease. Glucocorticoid receptor polymorphisms that alter glucocorticoid sensitivity may influence metabolic and cardiovascular risk factors in patients with AD. The 9β polymorphism of the glucocorticoid ...

Last Updated: 27 Jan 2014

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Addison's disease: a survey on 633 patients in Padova.
 

Author(s): Corrado Betterle, Riccardo Scarpa, Silvia Garelli, Luca Morlin, Francesca Lazzarotto, Fabio Presotto, Graziella Coco, Stefano Masiero, Anna Parolo, Maria Paola Albergoni, Roberta Favero, Susi Barollo, Monica Salvà, Daniela Basso, Shu Chen, Bernard Rees Smith, Jadwiga Furmaniak, Franco Mantero

Journal:

 

Addison's disease (AD) is a rare endocrine condition.

Last Updated: 22 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Addison's Disease" returned 2 free, full-text review articles on human participants. First 3 results:

Diagnosis--Addison's disease secondary to tuberculosis of the adrenal glands.
 

Author(s): Mrinal M Patnaik, Alaka K Deshpande

Journal: Clin Med Res. 2008 May;6(1):29.

 

Last Updated: 1 Jul 2008

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Autoimmunity in Addison's disease.
 

Author(s): P Martín Martorell, B O Roep, J W A Smit, P M Martorell

Journal: Neth J Med. 2002 Aug;60(7):269-75.

 

Addison's disease has a low incidence and is most frequently the result of an autoimmune disease in developed countries. Addison's disease can present as an isolated entity or in combination with other autoimmune diseases: Addison's disease can be part of the distinct polyglandular ...

Last Updated: 14 Nov 2002

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease
 

Status: Not yet recruiting

Condition Summary: Addison Disease

 

Last Updated: 24 Mar 2014

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Continuous Subcutaneous Hydrocortisone Infusion In Addison`s Disease and Type 1 Diabetes
 

Status: Recruiting

Condition Summary: Addison Disease; Type 1 Diabetes

 

Last Updated: 29 Nov 2013

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Exercise Capacity and Recovery in Addison's Disease
 

Status: Not yet recruiting

Condition Summary: Addison's Disease

 

Last Updated: 2 Aug 2012

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