Deafness

Common Name(s)

Deafness, Hearing loss

Hearing loss is considered to be anything from slight to profound impairment in the ability of a person to detect frequencies and intensities of sound. It can be acquired during life or present at birth, and it can also be inherited. Hearing loss can occur in one or both ears, and affect different areas of the ears. There are two main types of hearing loss; for more information see conductive hearing loss or sensorineural hearing loss. Deafness is the most profound form of hearing loss, where an individual can hear very little. In children, deafness is defined in children whose hearing loss is is greater than 90 dB, but hearing loss can also occur with age. Symptoms of hearing loss or deafness include delayed development of speech or unclear speech, use of high volume on electronic viewing devices, and consistent need to ask for repitition in conversation. Treatment for hearing loss may include hearing aides or cochlear implants to improve hearing ability.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Deafness" for support, advocacy or research.

Usher Syndrome Coalition

The Usher Syndrome Coalition's mission is to raise awareness and accelerate research for the most common cause of combined deafness and blindness. The Coalition also provides information and support to individuals and families affected by Usher syndrome.

Last Updated: 31 Oct 2014

View Details
Logo
Hands & Voices

Hands & Voices is dedicated to supporting families with children who are Deaf or Hard of Hearing without a bias around communication modes or methodology. We're a parent-driven, non-profit organization providing families with the resources, networks, and information they need to improve communication access and educational outcomes for their children. Our outreach activities, parent/professional collaboration, and advocacy efforts are focused on enabling Deaf and Hard-of-Hearing children to reach their highest potential.

Last Updated: 26 Mar 2013

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

View Details
Logo
Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Deafness" for support, advocacy or research.

Usher Syndrome Coalition

The Usher Syndrome Coalition's mission is to raise awareness and accelerate research for the most common cause of combined deafness and blindness. The Coalition also provides information and support to individuals and families affected by Usher syndrome.

http://www.usher-syndrome.org

Last Updated: 31 Oct 2014

View Details
Logo
Hands & Voices

Hands & Voices is dedicated to supporting families with children who are Deaf or Hard of Hearing without a bias around communication modes or methodology. We're a parent-driven, non-profit organization providing families with the resources, networks, and information they need to improve communication access and educational outcomes for their children. Our outreach activities, parent/professional collaboration, and advocacy efforts are focused on enabling Deaf and Hard-of-Hearing children to reach their highest potential.

http://www.handsandvoices.org

Last Updated: 26 Mar 2013

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

View Details
Logo
Zellweger Baby Support Network

This organization was started by a small group of parents whose lives have been affected in some way by a rare disorder. Our gift, in honor of our children, was to start this site, so we can help families and to raise awareness of these rare disorders. If your child has been diagnosed with Zellweger syndrome, a peroxisomal disorder or another rare disorder, we are here to help you. You are not alone! Our mission is to promote, advance, and improve awareness of Zellweger syndrome and other peroxisomal disorders, to assist, support, and aid, financially or otherwise, individuals and families affected by Zellweger syndrome. We will help you learn more about these disorders. We will provide emotional support, and we can help you to create a journal site for your child so that family and friends can be kept up to date on your child. We will pray with you and for you as you journey through life with your special angel. We know this is a hard time for you; you want answers, informa

http://www.zbsn.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

Usher Syndrome Registry

The Usher Syndrome Registry bridges the gap between researchers and patients. Building the registry is a fundamental step towards quickening the pace of discovery and ensuring access to patients as more clinical trials are launched.

Updated 31 Oct 2014

Go To URL
Usher Syndrome Conference Calls

The Coalition holds monthly conference calls in which leading experts talk about the latest news and research impacting families with Usher Syndrome. Live captioning is provided. Transcripts and past presentations can be found on our website.

Updated 31 Oct 2014

Go To URL
 
 
Top

Blogs

Usher Syndrome Blog

The Usher Syndrome Blog touches on a lot of issues that Usher families face.

Updated 31 Oct 2014

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Deafness" returned 687 free, full-text research articles on human participants. First 3 results:

Vasospasm causing reversible cortical deafness in subarachnoid hemorrhage.
 

Author(s): Raghvendra Ramdasi, Aadil Chagla, Amit Mahore

Journal: Neurol India. ;62(4):469-70.

 

Last Updated: 20 Sep 2014

Go To URL
A deafness-associated tRNAHis mutation alters the mitochondrial function, ROS production and membrane potential.
 

Author(s): Shasha Gong, Yanyan Peng, Pingping Jiang, Meng Wang, Mingjie Fan, Xinjian Wang, Hong Zhou, Huawei Li, Qingfeng Yan, Taosheng Huang, Min-Xin Guan

Journal: Nucleic Acids Res.. 2014 ;42(12):8039-48.

 

In this report, we investigated the molecular genetic mechanism underlying the deafness-associated mitochondrial tRNAHis 12201T>C mutation. The destabilization of a highly conserved base-pairing (5A-68U) by the m.12201T>C mutation alters structure and function of tRNAHis. Using cybrids ...

Last Updated: 4 Jul 2014

Go To URL
EPS8, encoding an actin-binding protein of cochlear hair cell stereocilia, is a new causal gene for autosomal recessive profound deafness.
 

Author(s): Asma Behlouli, Crystel Bonnet, Samia Abdi, Aïcha Bouaita, Andrea Lelli, Jean-Pierre Hardelin, Cataldo Schietroma, Yahia Rous, Malek Louha, Ahmed Cheknane, Hayet Lebdi, Kamel Boudjelida, Mohamed Makrelouf, Akila Zenati, Christine Petit

Journal:

 

Almost 90% of all cases of congenital, non-syndromic, severe to profound inherited deafness display an autosomal recessive mode of transmission (DFNB forms). To date, 47 causal DFNB genes have been identified, but many others remain to be discovered. We report the study of two siblings ...

Last Updated: 3 Jun 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Deafness" returned 45 free, full-text review articles on human participants. First 3 results:

Gene therapy for deafness.
 

Author(s): D C Kohrman, Y Raphael

Journal: Gene Ther.. 2013 Dec;20(12):1119-23.

 

Hearing loss is the most common sensory deficit in humans and can result from genetic, environmental or combined etiologies that prevent normal function of the cochlea, the peripheral sensory organ. Recent advances in understanding the genetic pathways that are critical for the development ...

Last Updated: 5 Dec 2013

Go To URL
Genetics of hearing and deafness.
 

Author(s): Simon Angeli, Xi Lin, Xue Zhong Liu

Journal: Anat Rec (Hoboken). 2012 Nov;295(11):1812-29.

 

This article is a review of the genes and genetic disorders that affect hearing in humans and a few selected mouse models of deafness. Genetics is playing an increasingly critical role in the practice of medicine. This is not only in part to the importance that genetic knowledge has ...

Last Updated: 23 Oct 2012

Go To URL
Genetics: advances in genetic testing for deafness.
 

Author(s): A Eliot Shearer, Richard J H Smith

Journal: Curr. Opin. Pediatr.. 2012 Dec;24(6):679-86.

 

To provide an update on recently discovered human deafness genes and to describe advances in comprehensive genetic testing platforms for deafness, both of which have been enabled by new massively parallel sequencing technologies.

Last Updated: 13 Nov 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Outcomes In Children With Developmental Delay And Deafness
 

Status: Recruiting

Condition Summary: Deafness; Hearing Loss

 

Last Updated: 8 Feb 2013

Go to URL
Efficacy, Safety, and Tolerability of Ancrod in Patients With Sudden Hearing Loss
 

Status: Recruiting

Condition Summary: Hearing Loss; Deafness; Hearing Loss, Sensorineural; Hearing Disorders; Ear Diseases

 

Last Updated: 22 Aug 2014

Go to URL
Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults With Partial Deafness
 

Status: Recruiting

Condition Summary: Hearing Loss; Partial Deafness; Hearing Disorders; Ear Diseases; Otorhinolaryngologic Diseases

 

Last Updated: 15 Oct 2014

Go to URL