Cutaneous T-cell lymphoma

Common Name(s)

Cutaneous T-cell lymphoma

Cutaneous T-cell lymphomas (CTCLs) are a group of disorders characterized by an abnormal accumulation of cancerous T-cells (a type of white blood cells) in the skin resulting in an itchy, red rash that can thicken or form a tumor. CTCLs belong to a larger group of disorders known asnon-Hodgkin's lymphomas. The most common types are mycosis fungoides and SŽzary syndrome. In some cases, cancerous T-cells may spread to the lymph nodes and eventually to other body tissues and organs, potentially resulting in life-threatening complications. The specific signs and symptoms vary from person to person. The exact cause of these conditions is unknown.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous T-cell lymphoma" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

Last Updated: 6 Jan 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous T-cell lymphoma" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

http://www.clfoundation.org

Last Updated: 6 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous T-cell lymphoma" returned 455 free, full-text research articles on human participants. First 3 results:

Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma: A case report and significance of timely ancillary testing.
 

Author(s): Vikas S Kavishwar, Chadha Kirti, Raut Kush, Kolekar Sunita, Chheda Pratiksha

Journal: Indian J Pathol Microbiol. ;59(1):131-2.

 

Last Updated: 10 Mar 2016

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Neoplastic Cells of Primary Cutaneous CD4+ Small/Medium-sized Pleomorphic T-cell Lymphoma Lack the Expression of Follicular T-helper Cell Defining Chemokine Receptor CXCR5.
 

Author(s): Dóra Krenács, Annamária Bakos, László Török, Lajos Kocsis, Enikő Bagdi, László Krenács

Journal: Acta Derm. Venereol.. 2016 Aug;96(6):850-2.

 

is missing (Short communication).

Last Updated: 23 Aug 2016

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Allogeneic Haematopoietic Stem Cell Transplantation for Patients with Cutaneous T-cell Lymphoma.
 

Author(s): Liisa Väkevä, Riitta Niittyvuopio, Sirpa Leppä, Jouni Heiskanen, Vesa Lindström, Annamari Ranki, Liisa Volin

Journal: Acta Derm. Venereol.. 2016 Aug;96(6):816-7.

 

is missing (Short communication).

Last Updated: 23 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous T-cell lymphoma" returned 41 free, full-text review articles on human participants. First 3 results:

Cutaneous T-cell lymphoma: 2016 update on diagnosis, risk-stratification, and management.
 

Author(s): Ryan A Wilcox

Journal: Am. J. Hematol.. 2016 Jan;91(1):151-65.

 

Cutaneous T-cell lymphomas are a heterogenous group of T-cell lymphoproliferative disorders involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS).

Last Updated: 15 Jan 2016

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Other Chemotherapeutic Agents in Cutaneous T-Cell Lymphoma.
 

Author(s): Catherine G Chung, Brian Poligone

Journal: Dermatol Clin. 2015 Oct;33(4):787-805.

 

Traditional chemotherapies, interleukins, phosphorylase inhibitors, and proteasome inhibitors are important therapies available to patients with cutaneous T-cell lymphoma (CTCL). Traditional chemotherapies, both in combination and as single agents, are commonly used in relapsed, refractory ...

Last Updated: 5 Oct 2015

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Histone Deacetylase Inhibitors for Cutaneous T-Cell Lymphoma.
 

Author(s): Madeleine Duvic

Journal: Dermatol Clin. 2015 Oct;33(4):757-64.

 

Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin's T-cell lymphomas that present as skin lesions. Mycosis fungoides with large cell transformation has a 5-year overall survival of 32% with involved skin and 7% with extracutaneous involvement. Failure to cure advanced MF with large ...

Last Updated: 5 Oct 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Micro Needle Array-Doxorubicin (MNA-D) in Patients With Cutaneous T-cell Lymphoma (CTCL)
 

Status: Recruiting

Condition Summary: Cutaneous T Cell Lymphoma

 

Last Updated: 23 Sep 2016

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A Trial of E7777 in Persistent and Recurrent Cutaneous T-Cell Lymphoma
 

Status: Recruiting

Condition Summary: Persistent or Recurrent Cutaneous T-Cell Lymphoma

 

Last Updated: 13 Dec 2016

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Poly ICLC, Radiation, and Romidepsin for Advanced Cutaneous T Cell Lymphoma
 

Status: Recruiting

Condition Summary: Cutaneous T-cell Lymphoma

 

Last Updated: 28 Dec 2016

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