Cutaneous Sclerosis

Common Name(s)

Cutaneous Sclerosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous Sclerosis" for support, advocacy or research.

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous Sclerosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous Sclerosis" returned 59 free, full-text research articles on human participants. First 3 results:

Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension.
 

Author(s): Stefania Lenna, Alessandra G Farina, Viktor Martyanov, Romy B Christmann, Tammara A Wood, Harrison W Farber, Raffaella Scorza, Michael L Whitfield, Robert Lafyatis, Maria Trojanowska

Journal: Arthritis Rheum.. 2013 May;65(5):1357-66.

 

Pulmonary arterial hypertension (PAH), a common complication of limited cutaneous systemic sclerosis (lcSSc), is associated with alterations of markers of inflammation and vascular damage in peripheral blood mononuclear cells (PBMCs). Endoplasmic reticulum (ER) stress and the unfolded ...

Last Updated: 24 Apr 2013

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Significance of palpable tendon friction rubs in early diffuse cutaneous systemic sclerosis.
 

Author(s): Adam Doré, Mary Lucas, Dana Ivanco, Thomas A Medsger, Robyn T Domsic

Journal: Arthritis Care Res (Hoboken). 2013 Aug;65(8):1385-9.

 

Palpable tendon friction rubs (TFRs) in systemic sclerosis (SSc; scleroderma) have been associated with diffuse skin thickening, increased disability, and poor survival. Our objective was to quantify the prognostic implications of palpable TFRs on the development of disease complications ...

Last Updated: 2 Aug 2013

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Topical rapamycin therapy to alleviate the cutaneous manifestations of tuberous sclerosis complex: a double-blind, randomized, controlled trial to evaluate the safety and efficacy of topically applied rapamycin.
 

Author(s): Mary Kay Koenig, Adelaide A Hebert, Joan Roberson, Joshua Samuels, John Slopis, Audrey Woerner, Hope Northrup

Journal: Drugs R D. 2012 Sep;12(3):121-6.

 

Facial angiofibromas are disfiguring facial lesions, present in up to 80% of patients with tuberous sclerosis complex. Recent elucidation of the complex cell signaling pathways that are disrupted in tuberous sclerosis indicates that rapamycin may be successful in alleviating the appearance ...

Last Updated: 6 Sep 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous Sclerosis" returned 1 free, full-text review articles on human participants. First 3 results:

[Efficacy of anti-thymocyte globulin and cyclosporin A combined therapy in aplastic anemia complicated with limited cutaneous systemic sclerosis].
 

Author(s): Eiichi Suematsu, Tomoya Miyamura, Kensaku Idutsu, Rumi Minami, Masahiro Yamamoto

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2005 Apr;28(2):99-103.

 

We reported here on a case of limited cutaneous systemic sclerosis (lcSSc) with aplastic anemia treated by anti-thymocyte globulin and cyclosporin A. The use of this therapy resulted not only in marrow recovery but also in resolution of the skin sclerosis. A 68 year-old woman was ...

Last Updated: 2 May 2005

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis
 

Status: Recruiting

Condition Summary: Diffuse Cutaneous Systemic Sclerosis

 

Last Updated: 5 Sep 2014

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Belimumab for the Treatment of Diffuse Cutaneous Systemic Sclerosis
 

Status: Recruiting

Condition Summary: Systemic Sclerosis

 

Last Updated: 15 Jan 2014

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CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma
 

Status: Recruiting

Condition Summary: Adult Lymphocyte Depletion Hodgkin Lymphoma; Adult Lymphocyte Predominant Hodgkin Lymphoma; Adult Mixed Cellularity Hodgkin Lymphoma; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Adult Nodular Sclerosis Hodgkin Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Hepatosplenic T-cell Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Large Granular Lymphocyte Leukemia

 

Last Updated: 17 Sep 2014

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