Cutaneous polyarteritis nodosa

Common Name(s)

Cutaneous polyarteritis nodosa

Cutaneous polyarteritis nodosa or cutaneous PAN, is a rare condition classified by inflammation of the blood vessels (responsible for transporting blood), particularly those that are in the deeper layers of the skin (cutaneous). Symptoms of cutaneous polyarteritis nodosa are sensitive bumps on the skin particularly in the lower leg and thigh region, circular welts that leave discolored patches after healing, regions of dead skin noted by their purple or black blisters, and a lace like purple pattern on the skin that surround lesions.

Skin biopsies (cell testing) of the lesions are the most common way to diagnose cutaneous polyarteritis nodosa. In most cases the cause of PAN is unknown; however in some cases, it is thought to be an over-reaction of the immune system to other infections such as Group A streptococcus, hepatitis B and C, HIV and Parvovirus or Fifth's disease. Treatment options include oral medications, ointments, or injections. It is important to consider the underlying cause, if known, to aid in treatment. Consult your doctor if you are experiencing any of these signs or symptoms. If untreated, cutaneous polyarteritis nodosa may worsen and spread to other body systems thus becoming systemic polyarteritis nodosa. If you or your family member has been diagnosed with cutaneous polyarteritis nodosa, talk with your doctor or specialist about the most current treatment options.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous polyarteritis nodosa" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous polyarteritis nodosa" returned 28 free, full-text research articles on human participants. First 3 results:

Cutaneous Polyarteritis Nodosa Associated with Destructive Arthritis.
 

Author(s): Lihi Atzmony, Hana Feuerman, Yair Molad, Yelena Didkovsky, Emmilia Hodak

Journal: Isr. Med. Assoc. J.. 2015 Sep;17(9):587-8.

 

Last Updated: 2 Dec 2015

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Cutaneous polyarteritis nodosa.
 

Author(s): María Alejandra Matteoda, Paola Cecilia Stefano, Marcela Bocián, María Marta Katsicas, Josefina Sala, Andrea Bettina Cervini

Journal: An Bras Dermatol. ;90(3 Suppl 1):188-90.

 

Polyarteritis nodosa is a rare vasculitis in children characterized by necrotizing inflammation in small and medium size arteries. It is classified into systemic and cutaneous PAN according to the presence of systemic symptoms or visceral involvement. We describe the case of a 14-year-old ...

Last Updated: 28 Aug 2015

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Cutaneous polyarteritis nodosa.
 

Author(s): Jayesh Sangani, Satarupa Mukherjee, Soumyadeep Biswas

Journal: Indian Pediatr. 2015 Apr;52(4):355.

 

Last Updated: 1 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous polyarteritis nodosa" returned 2 free, full-text review articles on human participants. First 3 results:

Cutaneous polyarteritis nodosa successfully treated with topical diflucortolone valerate: a case report & review of the literature.
 

Author(s): Ruby Haviv, Maya Capua, Jacob Amir, Liora Harel

Journal:

 

Cutaneous Polyarteritis Nodosa (cPAN) was first described in 1931. cPAN is considered a rare disease, its true incidence is unknown. The age of onset is diverse. Most studies have shown no significant gender predominance. cPAN presents with distinct skin findings, such as a maculopapular ...

Last Updated: 20 Oct 2014

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Case report and review of minocycline-induced cutaneous polyarteritis nodosa.
 

Author(s): Brent Culver, Aleksandr Itkin, Ken Pischel

Journal: Arthritis Rheum.. 2005 Jun;53(3):468-70.

 

Last Updated: 28 Jul 2005

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vasculitis Pregnancy Registry
 

Status: Recruiting

Condition Summary: Vasculitis; Behcet's Disease; CNS Vasculitis; Cryoglobulinemic Vasculitis; Eosinophilic Granulomatosis With Polyangiitis (EGPA); Churg-Strauss Syndrome (CSS); Granulomatosis With Polyangiitis (GPA); Wegener's Granulomatosis; IgA Vasculitis; Henoch-Schoenlein Purpura (HSP); Microscopic Polyangiitis (MPA); Polyarteritis Nodosa (PAN); Takayasu Arteritis (TAK); Urticarial Vasculitis; Systemic Vasculitis

 

Last Updated: 14 Jan 2016

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