Cutaneous lupus erythematosus

Common Name(s)

Cutaneous lupus erythematosus

Cutaneous lupus erythematosus is a form of lupus in which symptoms are limited to the skin and can cause various types of skin rashes. Lupus is an autoimmune disease. Autoimmune diseases occur when your body defense system attack its own healthy cells. Approximately 10% of people with cutaneous lupus erythematosus will develop systemic lupus (please also visit: systemic lupus erythematous) or potentially already have systemic lupus. There are three main categories of cutaneous lupus: chronic cutaneous lupus (CCLE), subacute cutaneous lupus (SCLE) and acute cutaneous lupus (ACLE). The type and location of rashes vary greatly depending on which form a person has. It is important to treat these lesions as they can become progressively worse and turn into skin cancer.

The primary cause of this condition is exposure to sunlight and most often affects women between ages 20-50. Prevention measures include the use of sunscreen or other barriers to prevent exposure to the sun (such as hats) as well as avoiding excess sun exposure during peak hours. Treatment may consist of steroid creams, injections and/or oral antibiotics to treat the skin symptoms. It is important to see a specialist to determine if other systemic symptoms may be present. Management of this condition requires a team of doctors. If you or a family member has been diagnosed with cutaneous lupus erythematosus, talk with your doctor and specialist about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous lupus erythematosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous lupus erythematosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous lupus erythematosus" returned 128 free, full-text research articles on human participants. First 3 results:

Intractable Cutaneous Nontuberculous Mycobacteriosis (Mycobacterium abscessus) during Treatment for Systemic Lupus Erythematosus.
 

Author(s): Dai Kishida, Mitsuto Sato, Chinatsu Kobayashi, Ken-Ichi Ueno, Tomomi Kinoshita, Minori Kodaira, Yasuhiro Shimojima, Wataru Ishii, Atsuhito Ushiki, Shu-Ichi Ikeda

Journal: Intern. Med.. 2017 ;56(10):1253-1257.

 

Mycobacterium abscessus infection tends to occur in patients with an advanced immunocompromised status. We encountered a case of intractable cutaneous M. abscessus infection that developed in a patient with systemic lupus erythematosus (SLE) during maintenance therapy. A 28-year-old ...

Last Updated: 15 May 2017

Go To URL
Neonatal lupus erythematosus: Report of a case with cutaneous, hematological and hepatobiliary findings.
 

Author(s): Andaç Salman, Merve Hatun Sarıçam, Ayşe Deniz Yücelten, Cuyan Demirkesen, Tülin Ergun

Journal: Turk. J. Pediatr.. 2016 ;58(1):106-108.

 

Neonatal lupus erythematosus is an autoimmune disorder mainly affecting the heart and skin. It is the most common cause of congenital heart block. In addition, hematological, hepatobiliary and neurological involvement may occur. Herein, we report a 23-day-old infant presented with ...

Last Updated: 6 Dec 2016

Go To URL
Risk of Cerebrovascular Accidents and Ischemic Heart Disease in Cutaneous Lupus Erythematosus: A Population-Based Cohort Study.
 

Author(s): Abha G Singh, Cynthia S Crowson, Siddharth Singh, Mark Denis, P Davis, Hilal Maradit-Kremers, Eric L Matteson, Vaidehi R Chowdhary

Journal: Arthritis Care Res (Hoboken). 2016 Nov;68(11):1664-1670.

 

It is unclear whether isolated cutaneous lupus erythematosus (CLE) affects cardiovascular risk. We estimated the cumulative incidence and mortality of cardiovascular diseases in a population-based CLE cohort and compared the risk with a matched non-CLE cohort.

Last Updated: 25 Mar 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous lupus erythematosus" returned 12 free, full-text review articles on human participants. First 3 results:

Prevalence of cutaneous warts in patients with systemic lupus erythematosus: a systematic review.
 

Author(s): Luisa Moreira Silva, Willer Goncalves Dourado Santos, Mittermayer Barretto Santiago

Journal:

 

The aim of this study was to review and evaluate systematically the scientific evidence on the relationship between systemic lupus erythematosus (SLE) and cutaneous warts (CW) caused by human papillomavirus (HPV) infection. With strict inclusion and exclusion criteria, we extensively ...

Last Updated: 3 Oct 2016

Go To URL
Cutaneous lupus erythematosus: updates on pathogenesis and associations with systemic lupus.
 

Author(s): Jasmine N Stannard, J Michelle Kahlenberg

Journal: Curr Opin Rheumatol. 2016 Sep;28(5):453-9.

 

Cutaneous lupus erythematosus (CLE) is a common manifestation among systemic lupus patients. There are no U.S. Food and Drug Administration approved therapies for CLE, and these lesions are frequently disfiguring and refractory to treatment. The present review will cover the recent ...

Last Updated: 28 Jul 2016

Go To URL
A systematic review and meta-analysis of cutaneous manifestations in late- versus early-onset systemic lupus erythematosus.
 

Author(s): Jennifer L Medlin, Karen E Hansen, Sara R Fitz, Christie M Bartels

Journal: Semin. Arthritis Rheum.. 2016 Jun;45(6):691-7.

 

Although systemic lupus erythematosus (SLE) most commonly occurs in reproductive-age women, some are diagnosed after the age of 50. Recognizing that greater than one-third of SLE criteria are cutaneous, we undertook a systematic review and meta-analysis to evaluate differences in ...

Last Updated: 24 May 2016

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus
 

Status: Recruiting

Condition Summary: Cutaneous Lupus Erythematosus

 

Last Updated: 24 Oct 2016

Go to URL

Last Updated: 19 Oct 2017

Go to URL
Study to Evaluate BIIB059 in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus; Active Cutaneous Lupus Erythematosus

 

Last Updated: 24 Aug 2017

Go to URL