Cutaneous lupus erythematosus

Common Name(s)

Cutaneous lupus erythematosus

Cutaneous lupus erythematosus is a form of lupus in which symptoms are limited to the skin and can cause various types of skin rashes. Lupus is an autoimmune disease. Autoimmune diseases occur when your body defense system attack its own healthy cells. Approximately 10% of people with cutaneous lupus erythematosus will develop systemic lupus (please also visit: systemic lupus erythematous) or potentially already have systemic lupus. There are three main categories of cutaneous lupus: chronic cutaneous lupus (CCLE), subacute cutaneous lupus (SCLE) and acute cutaneous lupus (ACLE). The type and location of rashes vary greatly depending on which form a person has. It is important to treat these lesions as they can become progressively worse and turn into skin cancer.

The primary cause of this condition is exposure to sunlight and most often affects women between ages 20-50. Prevention measures include the use of sunscreen or other barriers to prevent exposure to the sun (such as hats) as well as avoiding excess sun exposure during peak hours. Treatment may consist of steroid creams, injections and/or oral antibiotics to treat the skin symptoms. It is important to see a specialist to determine if other systemic symptoms may be present. Management of this condition requires a team of doctors. If you or a family member has been diagnosed with cutaneous lupus erythematosus, talk with your doctor and specialist about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cutaneous lupus erythematosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cutaneous lupus erythematosus" returned 127 free, full-text research articles on human participants. First 3 results:

Mast cells in systemic and cutaneous lupus erythematosus.
 

Author(s): Karolina Kaczmarczyk-Sekuła, Grzegorz Dyduch, Marcin Kostański, Dorota Wielowieyska-Szybińska, Joanna Szpor, Magdalena Białas, Krzysztof Okoń

Journal: Pol J Pathol. 2015 Dec;66(4):397-402.

 

Mast cells (MCs) are known to be regulators of inflammation and immunity, due to the released mediators and expressed cell surface molecules. Lupus erythematosus (LE) is a group of diseases which can be systemic or limited to the skin. Due to the fact that cytokines and chemokines ...

Last Updated: 23 Mar 2016

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Apoptosis in chronic cutaneous lupus erythematosus, discoid lupus, and lupus profundus.
 

Author(s): Claudia Ileana Sáenz-Corral, María Elisa Vega-Memíje, Eduwiges Martínez-Luna, Juan Carlos Cuevas-González, Alma Angélica Rodríguez-Carreón, Juan José Bollain-Y-Goytia de la Rosa, Felipe de Jesús Torres Del Muro, Esperanza Avalos-Díaz

Journal:

 

Lupus erythematosus is a multisystemic disease that is characterized by autoantibody production and immune complex deposition in such tissues as the mucosa, joints, the central nervous system, and skin. Cutaneous lupus erythematosus is categorized as acute, subacute, and chronic. ...

Last Updated: 11 Aug 2015

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[Cutaneous lupus erythematosus in a dog: reflections on human-animal evolutionary connections].
 

Author(s): Cristóbal Lecaros-Cornejo, Camila Lecaros-Cornejo, Sandra Díaz

Journal: Rev Med Chil. 2015 Mar;143(3):405-7.

 

Last Updated: 26 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cutaneous lupus erythematosus" returned 9 free, full-text review articles on human participants. First 3 results:

Pathophysiology of cutaneous lupus erythematosus.
 

Author(s): Jordan C Achtman, Victoria P Werth

Journal:

 

The pathophysiology of cutaneous lupus erythematosus (CLE) encompasses the complex interactions between genetics, the environment, and cells and their products. Recent data have provided enhanced understanding of these interactions and the mechanism by which they cause disease. A ...

Last Updated: 10 Aug 2015

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Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects.
 

Author(s): Jucélio Pereira Moura Filho, Raiza Luna Peixoto, Lívia Gomes Martins, Sillas Duarte de Melo, Ligiana Leite de Carvalho, Ana Karine F da Trindade C Pereira, Eutilia Andrade Medeiros Freire

Journal: An Bras Dermatol. ;89(1):118-25.

 

Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new criteria for the diagnosis of ...

Last Updated: 14 Mar 2014

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Cutaneous lupus erythematosus: diagnosis and treatment.
 

Author(s): L G Okon, V P Werth

Journal: Best Pract Res Clin Rheumatol. 2013 Jun;27(3):391-404.

 

Cutaneous lupus erythematosus (CLE) encompasses a wide range of dermatologic manifestations, which may or may not be associated with the development of systemic disease. Cutaneous lupus is divided into several sub-types, including acute CLE (ACLE), sub-acute CLE (SCLE) and chronic ...

Last Updated: 18 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus
 

Status: Recruiting

Condition Summary: Cutaneous Lupus Erythematosus

 

Last Updated: 20 Apr 2016

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Cutaneous Lupus Erythematosus and Elidel
 

Status: Recruiting

Condition Summary: Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Discoid

 

Last Updated: 5 Apr 2007

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Study to Evaluate BIIB059 in CLE With or Without SLE
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus (SLE); Active Cutaneous Lupus Erythematosus (CLE)

 

Last Updated: 19 Aug 2016

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