Craniopharyngioma

Common Name(s)

Craniopharyngioma

A craniopharyngioma is a slow-growing benign tumor that develops near the pituitary gland (a small endocrine gland at the base of the brain) and the hypothalamus (a small cone-shaped organ connected to the pituitary gland by nerves).  This tumor most commonly affects children between 5 and 10 years of age; however, adults can sometimes be affected.  Craniopharyngiomas are thought to arise from remnants of the craniopharyngeal duct and/or Rathke cleft or from metaplasia (abnormal transformation of cells) of squamous epithelial cell remnants of the stomadeum. Craniopharyngioma is treated with surgery alone or by surgery followed by radiation.

 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Craniopharyngioma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Craniopharyngioma" returned 139 free, full-text research articles on human participants. First 3 results:

Long term results after fractionated stereotactic radiotherapy (FSRT) in patients with craniopharyngioma: maximal tumor control with minimal side effects.
 

Author(s): Semi B Harrabi, Sebastian Adeberg, Thomas Welzel, Stefan Rieken, Daniel Habermehl, J├╝rgen Debus, Stephanie E Combs

Journal:

 

There are already numerous reports about high local control rates in patients with craniopharyngioma but there are only few studies with follow up times of more than 10 years. This study is an analysis of long term control, tumor response and side effects after fractionated stereotactic ...

Last Updated: 30 Sep 2014

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BRAF V600E mutations are characteristic for papillary craniopharyngioma and may coexist with CTNNB1-mutated adamantinomatous craniopharyngioma.
 

Author(s): Sarah Jane Larkin, Veronica Preda, Niki Karavitaki, Ashley Grossman, Olaf Ansorge

Journal: Acta Neuropathol.. 2014 ;127(6):927-9.

 

Last Updated: 19 May 2014

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Sleep-wake and melatonin pattern in craniopharyngioma patients.
 

Author(s): Line Pickering, Poul Jennum, Steen Gammeltoft, Lars Poulsgaard, Ulla Feldt-Rasmussen, Marianne Klose

Journal: Eur. J. Endocrinol.. 2014 Jun;170(6):873-84.

 

To assess the influence of craniopharyngioma or consequent surgery on melatonin secretion, and the association with fatigue, sleepiness, sleep pattern and sleep quality.

Last Updated: 19 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Craniopharyngioma" returned 13 free, full-text review articles on human participants. First 3 results:

Prevalence of neurobehavioral, social, and emotional dysfunction in patients treated for childhood craniopharyngioma: a systematic literature review.
 

Author(s): Gabriel Zada, Natalie Kintz, Mario Pulido, Lilyana Amezcua

Journal:

 

Craniopharyngiomas (CP) are locally invasive and frequently recurring neoplasms often resulting in neurological and endocrinological dysfunction in children. In addition, social-behavioral impairment is commonly reported following treatment for childhood CP, yet remains to be fully ...

Last Updated: 13 Nov 2013

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Suprasellar hemangioblastoma mimicking a craniopharyngioma: result of extended endoscopic transsphenoidal approach--case report.
 

Author(s): Tao Xie, Xiaobiao Zhang, Fan Hu, Xuejian Wang, Jian Wang, Yong Yu, Lingli Chen

Journal: Neurol. Med. Chir. (Tokyo). 2013 ;53(10):735-9.

 

Hemangioblastoma in the suprasellar region is rare. We present a case of a suprasellar hemangioblastoma that underwent surgical resection using an extended endoscopic transsphenoidal approach. A 64-year-old female patient presented with headache and decreased visual acuity for the ...

Last Updated: 28 Oct 2013

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[Biology of the craniopharyngioma].
 

Author(s): M A Kutin, D L Rotin, L V Shishkina, B A Kadashev

Journal: Zh Vopr Neirokhir Im N N Burdenko. 2013 ;77(1):53-60; discussion 61.

 

In the recent years a considerable number of different studies devoted to craniopharyngioma morphology were performed. There are more than 35 factors known up to date that could be related to the craniopharyngioma growth (Ki-67, p53, beta-catenin, p63, Retinoid acid receptors, Galectin-3, ...

Last Updated: 10 May 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prospective Study of Children and Adolescents With Craniopharyngioma
 

Status: Recruiting

Condition Summary: Craniopharyngioma; Obesity

 

Last Updated: 16 Apr 2015

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Last Updated: 26 Mar 2015

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Last Updated: 27 Apr 2015

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