Craniopharyngioma

Common Name(s)

Craniopharyngioma

A craniopharyngioma is a slow-growing benign tumor that develops near the pituitary gland (a small endocrine gland at the base of the brain) and the hypothalamus (a small cone-shaped organ connected to the pituitary gland by nerves).  This tumor most commonly affects children between 5 and 10 years of age; however, adults can sometimes be affected.  Craniopharyngiomas are thought to arise from remnants of the craniopharyngeal duct and/or Rathke cleft or from metaplasia (abnormal transformation of cells) of squamous epithelial cell remnants of the stomadeum. Craniopharyngioma is treated with surgery alone or by surgery followed by radiation.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Craniopharyngioma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Craniopharyngioma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Craniopharyngioma" returned 153 free, full-text research articles on human participants. First 3 results:

Identification of targets for rational pharmacological therapy in childhood craniopharyngioma.
 

Author(s): Jacob M Gump, Andrew M Donson, Diane K Birks, Vladimir M Amani, Karun K Rao, Andrea M Griesinger, B K Kleinschmidt-DeMasters, James M Johnston, Richard C E Anderson, Amy Rosenfeld, Michael Handler, Lia Gore, Nicholas Foreman, Todd C Hankinson

Journal:

 

Pediatric adamantinomatous craniopharyngioma (ACP) is a histologically benign but clinically aggressive brain tumor that arises from the sellar/suprasellar region. Despite a high survival rate with current surgical and radiation therapy (75-95 % at 10 years), ACP is associated with ...

Last Updated: 20 May 2015

Go To URL
An infrasellar craniopharyngioma involving the sphenoid sinus and clivus.
 

Author(s): Zhong Zhang, Ming-Yang Li, Yan-Wei Liu, Yong-Zhi Wang

Journal: Chin. Med. J.. 2015 Mar;128(6):844-5.

 

Last Updated: 11 Mar 2015

Go To URL
The importance of interdisciplinary communication with patients about complex, chronic illnesses: our experiences as parents of a child with a craniopharyngioma.
 

Author(s): Diana R Nemergut, Alan R Townsend

Journal: J. Pediatr. Endocrinol. Metab.. 2015 Jan;28(1-2):3-5.

 

Last Updated: 24 Dec 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Craniopharyngioma" returned 15 free, full-text review articles on human participants. First 3 results:

60 YEARS OF NEUROENDOCRINOLOGY: Biology of human craniopharyngioma: lessons from mouse models.
 

Author(s): Juan Pedro Martinez-Barbera

Journal: J. Endocrinol.. 2015 Aug;226(2):T161-72.

 

Adamantinomatous craniopharyngiomas (ACP) are clinically relevant tumours that are associated with high morbidity, poor quality of life and occasional mortality. Human and mouse studies have provided important insights into the biology of these aggressive tumours, and we are starting ...

Last Updated: 25 Jul 2015

Go To URL
Prevalence of neurobehavioral, social, and emotional dysfunction in patients treated for childhood craniopharyngioma: a systematic literature review.
 

Author(s): Gabriel Zada, Natalie Kintz, Mario Pulido, Lilyana Amezcua

Journal:

 

Craniopharyngiomas (CP) are locally invasive and frequently recurring neoplasms often resulting in neurological and endocrinological dysfunction in children. In addition, social-behavioral impairment is commonly reported following treatment for childhood CP, yet remains to be fully ...

Last Updated: 13 Nov 2013

Go To URL
Suprasellar hemangioblastoma mimicking a craniopharyngioma: result of extended endoscopic transsphenoidal approach--case report.
 

Author(s): Tao Xie, Xiaobiao Zhang, Fan Hu, Xuejian Wang, Jian Wang, Yong Yu, Lingli Chen

Journal: Neurol. Med. Chir. (Tokyo). 2013 ;53(10):735-9.

 

Hemangioblastoma in the suprasellar region is rare. We present a case of a suprasellar hemangioblastoma that underwent surgical resection using an extended endoscopic transsphenoidal approach. A 64-year-old female patient presented with headache and decreased visual acuity for the ...

Last Updated: 28 Oct 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Prospective Study of Children and Adolescents With Craniopharyngioma
 

Status: Recruiting

Condition Summary: Craniopharyngioma; Obesity

 

Last Updated: 16 Apr 2015

Go to URL

Last Updated: 11 Sep 2015

Go to URL

Last Updated: 27 Apr 2015

Go to URL