Acute Mountain Sickness

Common Name(s)

Acute Mountain Sickness

Acute mountain sickness is an illness caused by reduced air pressure and lower oxygen levels at high altitudes (usually above 8,000 feet or 2,400 meters). People at higher risk for acute mountain sickness are those who live at or near sea level and travel to a high altitude, or people who have had the illness before. The faster one climbs to a higher altitude, the more likely acute mountain sickness will occur. Signs and symptoms depend on the speed of ascension and the level of exertion, and can range from mild to life-threatening. Mild to moderate symptoms include difficulty sleeping, dizziness or light-headedness, fatigue, headache, loss of appetite, nausea or vomiting, rapid pulse, and shortness of breath with exertion. Symptoms of more severe acute mountain sickness include blue color to the skin, chest tightness or congestion, confusion, cough, coughing up blood, decreased consciousness, gray or pale complexion, cannot walk in a straight line or walk at all, shortness of breath at rest, and death due to lung problems or brain swelling.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acute Mountain Sickness" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acute Mountain Sickness" returned 114 free, full-text research articles on human participants. First 3 results:

Acute Mountain Sickness Symptom Severity at the South Pole: The Influence of Self-Selected Prophylaxis with Acetazolamide.
 

Author(s): Michael F Harrison, Paul J Anderson, Jacob B Johnson, Maile Richert, Andrew D Miller, Bruce D Johnson

Journal:

 

Acetazolamide, a carbonic anhydrase inhibitor, remains the only FDA approved pharmaceutical prophylaxis for acute mountain sickness (AMS) though its effectiveness after rapid transport in real world conditions is less clear.

Last Updated: 6 Feb 2016

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Metabolomic Analysis of Plasma From Patients With Acute Mountain Sickness Using Chromatography-Mass Spectrometry.
 

Author(s): Guoyan Zhu, Changlin Yin, Zhu Tian, Tinggang Wang, Wei Sun, Qiang Xiang, Guoning Guo

Journal: Medicine (Baltimore). 2015 Nov;94(45):e1988.

 

Although acute mountain sickness (AMS) has long been recognized, little is known about this condition to date. The current study was conducted to explore changes in the metabolomic profiles of AMS patients and to further assess the potential of using these changes for the diagnosis ...

Last Updated: 12 Nov 2015

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Principal Component Analysis and Risk Factors for Acute Mountain Sickness upon Acute Exposure at 3700 m.
 

Author(s): Shi-Zhu Bian, Jun Jin, Ji-Hang Zhang, Qian-Ning Li, Jie Yu, Shi-Yong Yu, Jian-Fei Chen, Xue-Jun Yu, Jun Qin, Lan Huang

Journal:

 

We aimed to describe the heterogeneity in the clinical presentation of acute mountain sickness (AMS) and to identify its primary risk factors.

Last Updated: 11 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acute Mountain Sickness" returned 13 free, full-text review articles on human participants. First 3 results:

Pro: pulse oximetry is useful in predicting acute mountain sickness.
 

Author(s): Buddha Basnyat

Journal: High Alt. Med. Biol.. 2014 Dec;15(4):440-1.

 

Last Updated: 23 Dec 2014

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Non-high altitude methods for rapid screening of susceptibility to acute mountain sickness.
 

Author(s): Han Song, Tao Ke, Wen-Jing Luo, Jing-Yuan Chen

Journal:

 

Acute mountain sickness (AMS) refers to the cerebral abnormalities typically triggered by exposure to hypobaric hypoxia at high altitude. Although AMS is not often life threatening, it can seriously impact health quality and decrease productivity. Thus, detection of potential susceptibility ...

Last Updated: 15 Nov 2013

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Identifying the lowest effective dose of acetazolamide for the prophylaxis of acute mountain sickness: systematic review and meta-analysis.
 

Author(s): Emma V Low, Anthony J Avery, Vaibhav Gupta, Angela Schedlbauer, Michael P W Grocott

Journal:

 

To assess the efficacy of three different daily doses of acetazolamide in the prevention of acute mountain sickness and to determine the lowest effective dose.

Last Updated: 19 Oct 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness
 

Status: Recruiting

Condition Summary: Acute Mountain Sickness; High Altitude Headache

 

Last Updated: 12 Sep 2016

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Controlled Hyperventilation as Prophylaxis for Acute Mountain Sickness
 

Status: Recruiting

Condition Summary: Altitude Sickness

 

Last Updated: 21 Nov 2016

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Inhaled Budesonide for Altitude Illness Prevention
 

Status: Not yet recruiting

Condition Summary: Altitude Sickness

 

Last Updated: 20 Oct 2016

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