Benign Familial Neonatal-Infantile Seizures

Common Name(s)

Benign Familial Neonatal-Infantile Seizures, Benign familial infantile seizures 3

Benign familial neonatal-infantile seizures is an autosomal dominant disorder in which afebrile seizures occur in clusters during the first year of life, without neurologic sequelae ({7:Shevell et al., 1986}). See also benign familial infantile seizures (BFIS1; {601764}), which has a slightly later onset, and benign neonatal seizures (see BFNS1; {121200}), which has a slightly earlier onset. See also early infantile epileptic encephalopathy-11 ({613721}), a more severe disorder that also results from mutations in the SCN2A gene.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Benign Familial Neonatal-Infantile Seizures" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Benign Familial Neonatal-Infantile Seizures" returned 1 free, full-text research articles on human participants. First 3 results:

Impaired NaV1.2 function and reduced cell surface expression in benign familial neonatal-infantile seizures.
 

Author(s): Sunita N Misra, Kristopher M Kahlig, Alfred L George

Journal: Epilepsia. 2008 Sep;49(9):1535-45.

 

Mutations in SCN2A, the gene encoding the brain voltage-gated sodium channel alpha-subunit Na(V)1.2, are associated with inherited epilepsies including benign familial neonatal-infantile seizures (BFNIS). Functional characterization of three BFNIS mutations was performed to identify ...

Last Updated: 10 Sep 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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