Constrictive Bronchiolitis

Common Name(s)

Constrictive Bronchiolitis

Constrictive bronchiolitis, also known as bronchiolitis obliterans, is a respiratory illness that affects the smallest air passages in the lungs, known as the bronchioles. Bronchioles normally control airflow in the lungs. Individuals with constrictive bronchiolitis have bronchioles that are compressed and narrowed by fibrosis (scar tissue) and/or inflammation (swelling). Symptoms may include shortness of breath, dry cough, or wheezing. Diagnositic testing may include a chest xray, chest cat scan (CT) and pulmonary function testing (measures the airflow in your lungs). Early inspiratory crackles may also be heard by your physician while listening to your lungs. Constrictive bronchiolitis may occur after a lung transplantation or a respiratory infection or due to exposure to certain toxic (poisonous) fumes or taking certain medications. Some connective tissue disorders also involve constrictive bronchiolitis. If the condition is due to inflammation, steriod treatments may be successful. If the condition is due to scarring, the damage is irreversible although steroid treatments may help manage the symptoms. The development of antifibrotic medications is rapidly progressing with advances in medical research. Talk with your doctor about treatment and management options if you or a family member has been diagnosed with constrictive bronchiolitis.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Constrictive Bronchiolitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Constrictive Bronchiolitis" returned 7 free, full-text research articles on human participants. First 3 results:

Constrictive bronchiolitis in soldiers returning from Iraq and Afghanistan.
 

Author(s): Matthew S King, Rosana Eisenberg, John H Newman, James J Tolle, Frank E Harrell, Hui Nian, Mathew Ninan, Eric S Lambright, James R Sheller, Joyce E Johnson, Robert F Miller

Journal: N. Engl. J. Med.. 2011 Jul;365(3):222-30.

 

In this descriptive case series, 80 soldiers from Fort Campbell, Kentucky, with inhalational exposures during service in Iraq and Afghanistan were evaluated for dyspnea on exertion that prevented them from meeting the U.S. Army's standards for physical fitness.

Last Updated: 21 Jul 2011

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Upregulation of elastin expression in constrictive bronchiolitis obliterans.
 

Author(s): Adrian Shifren, Jason C Woods, Daniel B Rosenbluth, Susan Officer, Joel D Cooper, Richard A Pierce

Journal: Int J Chron Obstruct Pulmon Dis. 2007 ;2(4):593-8.

 

Constrictive bronchiolitis obliterans is a fibrotic disease of small airways characterized by progressive obliteration of the airway lumen, with resulting obstructive pulmonary physiology. While previous work has demonstrated the collagenous nature of the constrictive fibrotic lesions, ...

Last Updated: 13 Feb 2008

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Improvement of refractory rheumatoid arthritis-associated constrictive bronchiolitis with etanercept.
 

Author(s): Alexis Benjamin Cortot, Vincent Cottin, Pierre Miossec, Eric Fauchon, Françoise Thivolet-Béjui, Jean-François Cordier

Journal: Respir Med. 2005 Apr;99(4):511-4.

 

Rheumatoid arthritis (RA)-associated constrictive bronchiolitis is a severe condition with no established efficient treatment. A 55-year-old woman with seropositive RA developed rapidly progressive constrictive bronchiolitis confirmed by lung biopsy. Her clinical condition worsened ...

Last Updated: 14 Mar 2005

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Constrictive Bronchiolitis" returned 1 free, full-text review articles on human participants. First 3 results:

Role of oxidants in interstitial lung diseases: pneumoconioses, constrictive bronchiolitis, and chronic tropical pulmonary eosinophilia.
 

Author(s): William N Rom

Journal: Mediators Inflamm.. 2011 ;2011():407657.

 

Oxidants such as superoxide anion, hydrogen peroxide, and myeloperoxidase from activated inflammatory cells in the lower respiratory tract contribute to inflammation and injury. Etiologic agents include inorganic particulates such as asbestos, silica, or coal mine dust or mixtures ...

Last Updated: 1 Dec 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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