Constipation

Common Name(s)

Constipation

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Constipation" for support, advocacy or research.

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Irritable Bowel Syndrome Self Help and Support Group

The Irritable Bowel Syndrome Self Help and Support Group is a patient led and patient governed organization dedicated to helping everyone who suffers from IBS and other digestive health disorders, through patient communication, support, symptoms, causes, treatment, accurate information and education.

Last Updated: 12 Oct 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Constipation" for support, advocacy or research.

Logo
Irritable Bowel Syndrome Self Help and Support Group

The Irritable Bowel Syndrome Self Help and Support Group is a patient led and patient governed organization dedicated to helping everyone who suffers from IBS and other digestive health disorders, through patient communication, support, symptoms, causes, treatment, accurate information and education.

http://www.ibsgroup.org

Last Updated: 12 Oct 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Constipation" returned 703 free, full-text research articles on human participants. First 3 results:

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation.
 

Author(s): Eike Floettmann, Khanh Bui, Mark Sostek, Kemal Payza, Michael Eldon

Journal: J. Pharmacol. Exp. Ther.. 2017 May;361(2):280-291.

 

Opioid-induced constipation (OIC) is a common side effect of opioid pharmacotherapy for the management of pain because opioid agonists bind to µ-opioid receptors in the enteric nervous system (ENS). Naloxegol, a polyethylene glycol derivative of naloxol, which is a derivative of ...

Last Updated: 24 Mar 2017

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Simultaneous degeneration of myenteric plexuses and pelvic parasympathetic colonic nerve in slow transit constipation: A case report.
 

Author(s): Zhiqiang Cheng, Kun Zhao, Dongsong Bi

Journal: Medicine (Baltimore). 2017 Mar;96(11):e6390.

 

Slow transit constipation (STC) is a common disease of which the etiology is still not clear. Multiple hypotheses have been proposed to explain STC, including autonomic neuropathy, disorders of the enteric nervous system and so forth. Morphological abnormalities of the enteric nerves ...

Last Updated: 15 Mar 2017

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Treatment Algorithm for Chronic Idiopathic Constipation and Constipation-Predominant Irritable Bowel Syndrome Derived from a Canadian National Survey and Needs Assessment on Choices of Therapeutic Agents.
 

Author(s): Yvonne Tse, David Armstrong, Christopher N Andrews, Alain Bitton, Brian Bressler, John Marshall, Louis W C Liu

Journal: Can J Gastroenterol Hepatol. 2017 ;2017():8612189.

 

Background. Chronic idiopathic constipation (CIC) and constipation-predominant irritable bowel syndrome (IBS-C) are common functional lower gastrointestinal disorders that impair patients' quality of life. In a national survey, we aimed to evaluate (1) Canadian physician practice ...

Last Updated: 8 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Constipation" returned 138 free, full-text review articles on human participants. First 3 results:

[Current Status of Translational Research on Constipation].
 

Author(s): Hyun Jik Lee, Kyung Sik Park

Journal: Korean J Gastroenterol. 2016 Sep;68(3):143-7.

 

Constipation is one of the most common gastrointestinal disorders with a prevalence up to 16.5% in the general population. It is frequently multifactorial and the pathophysiologic mechanism of constipation is not fully understood. Many preclinical studies of constipation have used ...

Last Updated: 20 Sep 2016

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Childhood constipation as an emerging public health problem.
 

Author(s): Shaman Rajindrajith, Niranga Manjuri Devanarayana, Bonaventure Jayasiri Crispus Perera, Marc Alexander Benninga

Journal: World J. Gastroenterol.. 2016 Aug;22(30):6864-75.

 

Functional constipation (FC) is a significant health problem in children and contrary to common belief, has serious ramifications on the lives of children and their families. It is defined by the Rome criteria which encourage the use of multiple clinical features for diagnosis. FC ...

Last Updated: 29 Aug 2016

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Aquaporins in the Colon as a New Therapeutic Target in Diarrhea and Constipation.
 

Author(s): Nobutomo Ikarashi, Risako Kon, Kiyoshi Sugiyama

Journal:

 

Aquaporins (AQPs) play important roles in the water transport system in the human body. There are currently 13 types of AQP, AQP0 through AQP12, which are expressed in various organs. Many members of the AQP family are expressed in the intestinal tract. AQP3 is predominantly expressed ...

Last Updated: 24 Jul 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Naloxegol in Cancer Opioid-Induced Constipation
 

Status: Recruiting

Condition Summary: Constipation

 

Last Updated: 27 Feb 2017

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Clinical Trial on Palliative Cancer Patients With Constipation
 

Status: Recruiting

Condition Summary: Constipation

 

Last Updated: 2 Dec 2016

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Study of Methylnaltrexone in Opioid-Induced Constipation Patients
 

Status: Recruiting

Condition Summary: Opioid-induced Constipation

 

Last Updated: 10 Oct 2015

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